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Condition: Diabetes
Procedure: Carotid Endarterectomy

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Total 106 results found since Jan 2013.

Early cardiovascular events in women with a history of gestational diabetes mellitus
Conclusions: A history of GDM was identified as a risk factor of CVD, especially coronary vascular diseases, within the 7 years postpartum. A lifestyle changes from postpartum onwards can be recommended and supported.
Source: Cardiovascular Diabetology - January 27, 2016 Category: Cardiology Authors: Karine GoueslardJonathan CottenetAnne-Sophie MarietMaurice GiroudYves CottinJean-Michel PetitCatherine Quantin Source Type: research

Circulating Chemerin Is Associated With Carotid Plaque Instability, Whereas Resistin Is Related to Cerebrovascular Symptomatology.
CONCLUSIONS: Low chemerin and high resistin levels were associated with carotid disease severity, suggesting that these adipokines may act as potential markers for plaque instability and stroke risk. Future studies are needed to assess causation between circulating adipokines and plaque instability. PMID: 27312219 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 15, 2016 Category: Cardiology Authors: Gasbarrino K, Mantzoros C, Gorgui J, Veinot JP, Lai C, Daskalopoulou SS Tags: Arterioscler Thromb Vasc Biol Source Type: research

O-042 Functional Outcome Prediction Model for Carotid Stenting Patients Using Admission Profiles: 29,453 patients using NIS data 2005 to 2013
ConclusionsAge (greater than 80), presence of symptoms including TIA, DM, CHF, COPD and CRF were identified to predict worse functional outcome after CAS.DisclosuresS. Park: None. M. Alexander: 1; C; : Investigator in CREST2 Trial. A. Rosengart: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Park, S., Alexander, M., Rosengart, A. Tags: Oral abstracts Source Type: research

Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial
This study is registered with ClinicalTrials.gov, number NCT00300976. Findings Between June 16, 2006, and March 31, 2009, 2542 eligible patients were randomly assigned to intensive therapy or conventional therapy (1271 in each group) and followed up for a median of 8·5 years (IQR 7·3–9·0). Two patients in the intensive therapy group were found to be ineligible after randomisation and were excluded from the analyses. During the intervention period, mean HbA1c, systolic blood pressure, diastolic blood pressure, and LDL cholesterol concentrations were significantly lower in the intensive therapy group than in the convent...
Source: The Lancet Diabetes and Endocrinology - October 25, 2017 Category: Endocrinology Source Type: research

Early Outcomes of Routine Delayed Shunting in Carotid Endarterectomy for Asymptomatic Patients.
CONCLUSIONS: Routine delayed shunting associated with standardisation of the technique seems to be a safe and effective technique and contributes to maintaining the RNCR < 1% over time and independently from operators and other clinical factors. PMID: 30037739 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - July 20, 2018 Category: Surgery Authors: Piazza M, Zavatta M, Lamaina M, Taglialavoro J, Squizzato F, Grego F, Antonello M Tags: Eur J Vasc Endovasc Surg Source Type: research

Effect of severe contralateral carotid stenosis or occlusion on early and late outcomes after carotid endarterectomy.
Conclusion: There were no significant differences in MACE incidence after CEA between the non-SCSO and SCSO groups, and preexisting SCSO was not associated with an increased risk of perioperative or long-term MACE occurrence. PMID: 31620394 [PubMed]
Source: Annals of Surgical Treatment and Research - October 18, 2019 Category: Surgery Tags: Ann Surg Treat Res Source Type: research

The Diagnostic Accuracy of Intra-Operative Near Infrared Spectroscopy in Carotid Artery Endarterectomy Under Regional Anaesthesia: Systematic Review and Meta-Analysis
CONCLUSION: The results of this study suggest that NIRS as a cerebral monitoring technique does not have sufficiently high sensitivity or specificity to be used alone in the neurological monitoring of patients undergoing CEA under RA.PMID:34284934 | DOI:10.1016/j.ejvs.2021.05.042
Source: PubMed: Eur J Vasc Endovasc ... - July 21, 2021 Category: Surgery Authors: Lu ís Duarte-Gamas Ant ónio Pereira-Neves Joel Sousa Bernardo Sousa-Pinto Jo ão Rocha-Neves Source Type: research

Investigation of Combined Carotid Endarterectomy and Coronary Artery Bypass Graft Surgery Outcomes and Adverse Event Risk Factors in the Vascular Quality Initiative
CONCLUSIONS: Combined CEA and CABG provides excellent long-term mortality prevention in patients with co-existing severe coronary and carotid atherosclerosis. Simultaneous CEA and CABG provides equivalent stroke prevention and long-term survival to both a cohort of patients undergoing coronary revascularization within 5 years of CEA and patients undergoing isolated CEA or CABG in the literature. The two most impactful modifiable risk factors towards long-term stroke and mortality prevention for patients undergoing simultaneous CEA-CABG are patch placement at CEA site and adherence to statin medication therapy.PMID:37303074...
Source: Atherosclerosis - June 11, 2023 Category: Cardiology Authors: Ashley Penton Jonathan Lin Grant Kolde Matthew DeJong Matthew Blecha Source Type: research

Optimal selection of asymptomatic patients for carotid endarterectomy based on predicted 5-year survival
We examined factors associated with 5-year survival following CEA in patients with asymptomatic internal carotid artery (ICA) stenosis.Methods: Prospectively collected data from 4114 isolated CEAs performed for asymptomatic stenosis across 24 centers in the Vascular Study Group of New England between 2003 and 2011 were used for this analysis. Late survival was determined with the Social Security Death Index. Cox proportional hazard models were used to identify risk factors for mortality within the first 5 years after CEA and to calculate a risk score for predicting 5-year survival.Results: Overall 3- and 5-year survival af...
Source: Journal of Vascular Surgery - March 13, 2013 Category: Surgery Authors: Jessica B. Wallaert, Jack L. Cronenwett, Daniel J. Bertges, Andres Schanzer, Brian W. Nolan, Randall De Martino, Jens Eldrup-Jorgensen, Philip P. Goodney, Vascular Study Group of New England Tags: Clinical research studies Source Type: research

Comparison of Carotid Artery Stenting and Carotid Endarterectomy in Patients with Symptomatic Carotid Artery Stenosis: A Single Center Study.
CONCLUSION: In our trial of patients with symptomatic carotid artery stenosis, no significant difference could be shown in periprocedural outcomes, postprocedural outcomes except TIA, and in composite endpoints between the CEA and CAS groups. CAS is a safe and efficacious alternative for the treatment of symptomatic carotid artery stenosis. PMID: 24105435 [PubMed - as supplied by publisher]
Source: Advances in Therapy - October 9, 2013 Category: Drugs & Pharmacology Authors: Taş MH, Simşek Z, Colak A, Koza Y, Demir P, Demir R, Kaya U, Tanboga IH, Gundogdu F, Sevimli S Tags: Adv Ther Source Type: research

A Risk Prediction Model for Determining Appropriateness of CEA in Patients With Asymptomatic Carotid Artery Stenosis
A scoring system based on the probability of long-term survival can be used to determine patients most likely to benefit from carotid endarterectomy (CEA). There is considerable controversy about which patients with asymptomatic carotid stenosis, even high-grade asymptomatic carotid stenosis, are most likely to benefit from a prophylactic CEA. Indeed, there are those who believe that asymptomatic carotid stenosis may be best treated with carotid artery stenting and those who also contend that with modern medical therapy, asymptomatic carotid stenosis may be best treated with medical therapy alone. Although it seems intuit...
Source: Journal of Vascular Surgery - March 24, 2014 Category: Surgery Authors: M.F. Conrad, J. Kang, S. Mukhopadhyay Tags: Abstracts Source Type: research

Treatment with betablockers is associated with higher grey-scale median in carotid plaques
Conclusions: These results suggest the use of standardized ultrasound techniques as an important tool in evaluating the effect of anti-atherosclerotic medications and underline the need of.further prospective randomized studies on larger patient cohorts in order to confirm these results.
Source: BMC Cardiovascular Disorders - August 30, 2014 Category: Cardiology Authors: Giuseppe AsciuttoNuno DiasAna PerssonJan NilssonIsabel Gonçalves Source Type: research

Effect of Statins on Early and Late Clinical Outcomes of Carotid Endarterectomy and the Rate of Post-Carotid Endarterectomy Restenosis
A retrospective analysis of prospectively collected data on 500 consecutive CEAs followed routinely at 1, 6, and 12 months and every year thereafter. Statins significantly lowered death rates in diabetics and tended to lower both death and stroke rates in diabetics and patients with hypercholesterolemia. Statins had no effect on post-CEA restenosis.
Source: Journal of the American College of Surgeons - December 15, 2014 Category: Surgery Authors: Ali F. AbuRahma, Mohit Srivastava, Patrick A. Stone, Bryan K. Richmond, Zachary AbuRahma, Will Jackson, L Scott Dean, Albeir Y. Mousa Source Type: research

Discussion
DR ERIC ENDEAN (Lexington, KY): The authors have presented a provocative study that has investigated the early and late effect of statins on patients undergoing carotid endarterectomy. The authors retrospectively evaluated 500 patients, 60% of whom were taking statins and 40% without statins. Interestingly, among the patients taking statins, they found a higher incidence of diabetes and, as would be expected, hypercholesterolemia. To the author's credit, there was a low incidence of stroke, MI, and death.
Source: Journal of the American College of Surgeons - March 21, 2015 Category: Surgery Tags: Southern surgical association article Source Type: research