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Suicide Following Stroke in the United States Veterans Health Administration Population
In the United States (US), suicide is a leading cause of death, and most of these suicides involve firearms, highlighting the importance of lethal means safety in suicide prevention.(1, 2) US Veterans experience a suicide rate 1.5 times higher than US civilian adults and are more likely to use firearms as the means of suicide.(3) Risk factors for suicide within this population include demographic factors such as sex, age, race, and level of education, as well as health factors such as smoking status, psychiatric conditions (e.g., posttraumatic stress disorder [PTSD], depression, bipolar and anxiety disorders, schizophrenia...
Source: Archives of Physical Medicine and Rehabilitation - March 31, 2021 Category: Rehabilitation Authors: Jordan M. Wyrwa, Tyler M. Shirel, Trisha A. Hostetter, Alexandra L. Schneider, Claire A. Hoffmire, Kelly A. Stearns-Yoder, Jeri E. Forster, Nathan E. Odom, Lisa A. Brenner Tags: Original Research Source Type: research
Estimating Insulin Resistance May Help Predict Stroke, Death in T2D Estimating Insulin Resistance May Help Predict Stroke, Death in T2D
Calculating the estimated glucose disposal rate as a proxy for the level of insulin resistance may be useful way to determine if someone with type 2 diabetes is at risk for having a first stroke, Swedish researchers have found.Medscape Medical News
Source: Medscape Medical News Headlines - October 21, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Medical News Today: Higher risk of stroke can follow midlife type 2 diabetes
A study of twins in Sweden links a 30% higher risk in older age of brain artery blockage, which stroke often follows, to type 2 diabetes in middle age.
Source: Health News from Medical News Today - June 12, 2019 Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news
Risk of stroke in patients with heart failure and sinus rhythm: data from the Swedish Heart Failure Registry
ConclusionsIn terms of absolute risk, only 27.6% of patients had an annual IS incidence of ≤1%. To which extent this would be amenable to anticoagulant treatment remains conjectural. A score compiling age and specific co‐morbidities identified HF‐SR patients with increased risk of IS with modest discriminative ability.
Source: ESC Heart Failure - November 9, 2020 Category: Cardiology Authors: Clara Hjalmarsson,
Michael Fu,
Tatiana Zverkova Sandstr öm,
Maria Schaufelberger,
Charlotta Ljungman,
Björn Andersson,
Entela Bollano,
Ulf Dahlström,
Annika Rosengren Tags: Original Research Article Source Type: research
Cardiovascular Event Rates After Myocardial Infarction or Ischaemic Stroke in Patients with Additional Risk Factors: A Retrospective Population-Based Cohort Study
ConclusionDespite previous use of moderate- or high-intensity statins, patients with a history of MI or IS, and additional risk factors remain at very high cardiovascular risk.
Source: Advances in Therapy - July 26, 2021 Category: Drugs & Pharmacology Source Type: research
Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion
Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin.
Ethics Statement
This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research
Long working week 'may increase risk of irregular heartbeat'
Conclusion
This study draws together data from a large group of people to investigate whether working hours could be linked to AF.
It found people who work 55 or more hours a week had an increased risk of developing an irregular heartbeat.
But before we jump to any conclusions, there are several important things to consider:
The number of people who developed AF during this study was small: only 1.24%. That's the absolute risk of AF. Even if working more than 55 hours a week does increase your risk of AF by around 40%, it would only be increasing it to something like 1.74% – which is still very small.
Only a small ...
Source: NHS News Feed - July 14, 2017 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Source Type: news
Any type of physical exercise is good for the heart
Conclusion
This study shows that all physical activity, in any form, is good for us. This includes both recreational and non-recreational activities.
Don't be misled by some of the media: non-recreational activities like housework are not "better" than recreational activities like playing sports or going to the gym.
The fact that reduced risk was seen with non-recreational activity across all countries, but only seen with recreational activity in high-income countries was probably just because fewer people in lower-income countries play sports or go to the gym.
The researchers estimate that 8% of all deaths and...
Source: NHS News Feed - September 22, 2017 Category: Consumer Health News Tags: Lifestyle/exercise Source Type: news
Blood-thinning drugs may reduce dementia risk in people with irregular heartbeats
Conclusion
If you’ve been diagnosed with AF and you have been prescribed anticoagulant treatments such as warfarin or clopidogrel, we already know they protect you against having a stroke. This study suggests they may also help to protect you against dementia.
Cutting the risk of dementia for people who have a raised risk because of AF would be an exciting step forward. Unfortunately, we can’t tell from this study whether the protection against dementia was down to the anticoagulants, because of the possible effect of unmeasured confounding factors.
Usually, we would want to see a randomised controlled trial (RCT) to f...
Source: NHS News Feed - October 25, 2017 Category: Consumer Health News Tags: Neurology Source Type: news
Periodontal Disease Is Associated With Increased Risk of Hypertension: A Cross-Sectional Study
Conclusion: Periodontal disease is significantly and positively correlated with increased risk of hypertension in Chinese population, and exact mechanisms of this association should be explored in future.
Introduction
Periodontal disease is a complex polymicrobial inflammation, including gingivitis and periodontitis. According to the 2015 Global Burden of Disease (GBD) study, the prevalence of severe chronic periodontitis in 2015 has reached 616 million (Kassebaum et al., 2017). In China, the periodontal disease standardized DALYs rate has risen from 24.7 in 1990 to 25.7 in 2013 according to the data from 2013 GBD ...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research
Higher long-term cardiovascular morbidity after open surgery for intermittent claudication caused by infrainguinal atherosclerotic disease in patients with diabetes - a nationwide observational cohort study.
Conclusions: DM patients showed higher rates of MACE and AMI in propensity score adjusted analysis five years after planned infrainguinal open surgery for IC. Higher HbA1c was associated with MACE, stroke, and total mortality in patients with DM, whereas longer duration of DM was associated with major amputation.
PMID: 33334201 [PubMed - as supplied by publisher]
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - December 18, 2020 Category: Surgery Authors: Dakhel A, Zarrouk M, Ekelund J, Acosta S, Miftaraj M, Eliasson B, Svensson AM, Gottsäter A Tags: Vasa Source Type: research
Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study
Publication date: 11–17 August 2018Source: The Lancet, Volume 392, Issue 10146Author(s): Araz Rawshani, Naveed Sattar, Stefan Franzén, Aidin Rawshani, Andrew T Hattersley, Ann-Marie Svensson, Björn Eliasson, Soffia GudbjörnsdottirSummaryBackgroundPeople with type 1 diabetes are at elevated risk of mortality and cardiovascular disease, yet current guidelines do not consider age of onset as an important risk stratifier. We aimed to examine how age at diagnosis of type 1 diabetes relates to excess mortality and cardiovascular risk.MethodsWe did a nationwide, register-based cohort study of individuals with type 1 diabetes...
Source: The Lancet - August 10, 2018 Category: General Medicine Source Type: research
Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profile backed by ove...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
High Blood Pressure and Diabetes Are Linked. Here ’ s How to Reduce Your Risk for Both
High blood pressure—also known as hypertension—and Type 2 diabetes are two of the most common medical conditions in the U.S. Unfortunately, they often occur together. Some research has found that 85% of middle-aged or older adults who have Type 2 diabetes also have hypertension, and both conditions elevate a person’s risk for heart disease, stroke, and kidney disease.
These increased risks are significant, and in some cases grave. Researchers have found that people with Type 2 diabetes are up to four times more likely to develop cardiovascular disease than those who don’t have the conditio...
Source: TIME: Health - August 29, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Disease freelance healthscienceclimate Source Type: news
