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Condition: Reflex Sympathetic Dystrophy

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Total 1447 results found since Jan 2013.

Exploiting Interlimb Arm and Leg Connections for Walking Rehabilitation: A Training Intervention in Stroke.
Abstract Rhythmic arm and leg (A&L) movements share common elements of neural control. The extent to which A&L cycling training can lead to training adaptations which transfer to improved walking function remains untested. The purpose of this study was to test the efficacy of A&L cycling training as a modality to improve locomotor function after stroke. Nineteen chronic stroke (>six months) participants were recruited and performed 30 minutes of A&L cycling training three times a week for five weeks. Changes in walking function were assessed with (1) clinical tests; (2) strength during isometric...
Source: Neural Plasticity - July 14, 2016 Category: Neurology Authors: Klarner T, Barss TS, Sun Y, Kaupp C, Loadman PM, Zehr EP Tags: Neural Plast Source Type: research

Unique cytokine and chemokine responses to exertional heat stroke in mice
In this study we used a recently developed mouse EHS model to measure the responses of circulating cytokines/chemokines and cytokine gene expression in muscle. A very rapid increase in circulating IL-6 was observed at maximum core temperature (Tc,max) that peaked at 0.5 h of recovery and disappeared by 3 h. IL-10 was not elevated at any time. This contrasts with PHS where both IL-6 and IL-10 peak at 3 h of recovery. Keratinocyte chemoattractant (KC), granulocyte-colony-stimulating factor (G-CSF), macrophage inflammatory protein (MIP)-2, MIP-1β, and monocyte chemoattractive factor-1 also demonstrated near peak response...
Source: Journal of Applied Physiology - February 2, 2017 Category: Physiology Authors: King, M. A., Leon, L. R., Morse, D. A., Clanton, T. L. Tags: RESEARCH ARTICLE Source Type: research

A single group, pretest-posttest clinical trial for the effects of dry needling on wrist flexors spasticity after stroke.
CONCLUSIONS: This study suggests that DN reduced wrist flexors spasticity and alpha motor neuron excitability in patients with stroke, and improvements persisted for one hour after DN. PMID: 28222554 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - February 24, 2017 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Dual-afferent sensory input training for voluntary movement after stroke: A pilot randomized controlled study.
CONCLUSIONS: DASI stimulates voluntary movement in patients, causes rapid activation of the cerebral cortex, and reduces excessive excitation of spinal motor neurons. Therefore, DASI, which stimulates voluntary movement, has a greater effect on brain activation in stroke patients. PMID: 28222553 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - February 24, 2017 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Stroke ‐Induced Chronic Systolic Dysfunction Driven by Sympathetic Overactivity
This article is protected by copyright. All rights reserved.
Source: Annals of Neurology - October 10, 2017 Category: Neurology Authors: Michael Bieber, Rudolf A. Werner, Edit Tanai, Ulrich Hofmann, Takahiro Higuchi, Kai Schuh, Peter U. Heuschmann, Stefan Frantz, Oliver Ritter, Peter Kraft, Christoph Kleinschnitz Tags: Research Article Source Type: research

Increase of Substance P Concentration in Saliva after Pharyngeal Electrical Stimulation in Severely Dysphagic Stroke Patients - an Indicator of Decannulation Success?
CONCLUSIONS: The physiological mechanism of PES may consist in restoration of sensory feedback, which is known to be crucial for the execution of a safe swallow. SP possibly acts as a biomarker for indicating response to PES. PMID: 29041008 [PubMed - as supplied by publisher]
Source: Neuro-Signals - October 17, 2017 Category: Neurology Authors: Muhle P, Suntrup-Krueger S, Bittner S, Ruck T, Claus I, Marian T, Schröder JB, Minnerup J, Warnecke T, Meuth SG, Dziewas R Tags: Neurosignals Source Type: research

Relationship Between Frequency of Spontaneous Swallowing and Salivary Substance P Level in Patients with Acute Stroke
In conclusion, the frequency of spontaneous swallowing was decreased in acute stroke patients with low salivary SP levels. Salivary SP levels can be potentially a useful biomarker of risk of stroke-associated pneumonia in the acute stage.
Source: Dysphagia - November 28, 2017 Category: Speech-Language Pathology Source Type: research

Progressive recruitment of contralesional cortico-reticulospinal pathways drives motor impairment post stroke.
Abstract KEY POINTS: Activation of the shoulder abductor muscles in the arm opposite a unilateral brain injury causes involuntary increases in elbow, wrist and finger flexion in the same arm, a phenomenon referred to as the flexion synergy. It has been proposed that flexion synergy expression is related to reduced output from ipsilesional motor cortex and corticospinal pathways. In this human subjects study, we provide evidence that the magnitude of flexion synergy expression is instead related to a progressive, task-dependent recruitment of contralesional cortex. We also provide evidence that recruitment of contr...
Source: The Journal of Physiology - February 19, 2018 Category: Physiology Authors: McPherson JG, Chen A, Ellis MD, Yao J, Heckman CJ, Dewald JPA Tags: J Physiol Source Type: research

Adrenal hormones and circulating leukocyte subtypes in stroke patients treated with reperfusion therapy
Publication date: Available online 13 March 2018 Source:Brain, Behavior, and Immunity Author(s): Francesc Miró-Mur, Carlos Laredo MsC, Arturo Renú, Salvatore Rudilosso, Yashu Zhao, Sergio Amaro, Laura Llull, Xabier Urra, Anna M. Planas, Ángel Chamorro Ischemic stroke sets in motion a dialogue between the central nervous and the immune systems that includes the sympathetic/adrenal system. We investigated the course of immune cells and adrenocortical and adrenomedullary effectors in a cohort of 51 patients with acute stroke receiving reperfusion therapy (intravenous alteplase or mechanical thrombectomy) and its correlati...
Source: Brain, Behavior, and Immunity - March 14, 2018 Category: Neurology Source Type: research

Implementing Cough Reflex Testing in a Clinical Pathway for Acute Stroke: A Pragmatic Randomised Controlled Trial
In conclusion, it was possible to implement a CRT pathway with minimal increases in clinician resources. While clinicians perceived CRT as beneficial in clinical decision making, the efficacy of C RT for reducing pneumonia rates in acute stroke remains to be established.Clinical Trial Registration-URL:http://www.anzctr.org.au. Unique identifier: ACTRN12616000724471
Source: Dysphagia - May 15, 2018 Category: Speech-Language Pathology Source Type: research

Adrenal hormones and circulating leukocyte subtypes in stroke patients treated with reperfusion therapy
Publication date: May 2018Source: Brain, Behavior, and Immunity, Volume 70Author(s): Francesc Miró-Mur, Carlos Laredo, Arturo Renú, Salvatore Rudilosso, Yashu Zhao, Sergio Amaro, Laura Llull, Xabier Urra, Anna M. Planas, Ángel ChamorroAbstractIschemic stroke sets in motion a dialogue between the central nervous and the immune systems that includes the sympathetic/adrenal system. We investigated the course of immune cells and adrenocortical and adrenomedullary effectors in a cohort of 51 patients with acute stroke receiving reperfusion therapy (intravenous alteplase or mechanical thrombectomy) and its correlation with st...
Source: Brain, Behavior, and Immunity - July 5, 2018 Category: Neurology Source Type: research

Stroke in supplementary motor area mimicking functional disorder: a case report
We report a 59-year-old man with previous history for myocardial infarction, referred to emergency room with an acute dense right-side hemiplegia, positive Hoover sign, asymmetrical Babinski responses and intermittent ability to move his arm in some specific reflex actions despite plegia. Since brain computed tomography scan was unremarkable we could not be sure whether his symptoms were organic or functional until a diffusion weighted imaging of magnetic resonance imaging elucidated the situation. To our knowledge, there is only one case report in the literature prior to ours, presenting a supplementary motor area stroke ...
Source: Journal of Neurology - September 28, 2019 Category: Neurology Source Type: research

Neurogenic pulmonary edema following acute stroke: The progress and perspective.
Abstract Neurogenic pulmonary edema (NPE) following acute stroke is an acute respiratory distress syndrome (ARDS) with clinical characteristics that include acute onset, apparent pulmonary interstitial fluid infiltration and rapid resolution. The pathological process of NPE centers on sympathetic stimulation and fulminant release of catecholamines, which cause contraction of resistance vessels. Elevated systemic resistance forces fluid into pulmonary circulation, while pulmonary circulation overload induces pulmonary capillary pressure that elevates, and in turn damages the alveolar capillary barrier. Damage to th...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 29, 2020 Category: Drugs & Pharmacology Authors: Zhao J, Xuan NX, Cui W, Tian BP Tags: Biomed Pharmacother Source Type: research

Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke.
Conclusion: LSG ablation could reduce VAs vulnerability after acute stroke by preventing the macrophages polarization and activation induced by sympathetic hyperactivity. PMID: 33456346 [PubMed - in process]
Source: International Journal of Medical Sciences - January 20, 2021 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study
ConclusionsObstructive sleep apnea with comorbid ischemic stroke may be a distinctive phenotype which responds quite well to trazodone, decreasing OSA severity without increasing nocturnal hypoxia.Trial RegistrationClinicaltrials.gov: NCT04162743, 2019/11/10.
Source: Journal of Neurology - February 24, 2021 Category: Neurology Source Type: research