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Specialty: Geriatrics
Condition: Depression

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Total 194 results found since Jan 2013.

A stroke of bad luck: new-onset mania in elderly patient following undetected stroke, a case report
The phenomenon of developing depression after a stroke is fairly common in the literature (29%) but developing mania after a stroke is rare reportedly to be 1-2% of stroke survivors (Starkstein). One of the earliest descriptions of mania after stroke was described in 1989 of the right hemisphere (Starkstein). In 2011, a systematic review looking at 32 studies identified 49 cases describing symptoms of mania post-stroke. At initial presentation, 92% of these patients presented with elevated mood, 71% with increased rate of speech, 69% with insomnia and 63% with agitation (Santos).
Source: The American Journal of Geriatric Psychiatry - March 14, 2020 Category: Geriatrics Authors: Carolina Osorio, Stephanie Bolton, Hans von Walter, Mamdouh Hanna Tags: Poster Number: NR - 21 Source Type: research

Dimensions of post-stroke depression and neuropsychological deficits in older adults
Stroke is the leading cause of both serious and long-term disability and the fifth leading cause of death in the United States.1,2 Post-stroke depression (PSD) afflicts approximately one-fourth of stroke survivors and increases the likelihood of persistent disability.3-6 Prompt identification and treatment of PSD can improve affective symptoms and stroke related disability.7,8
Source: The American Journal of Geriatric Psychiatry - January 24, 2020 Category: Geriatrics Authors: Dora Kanellopoulos, Victoria Wilkins, Jimmy Avari, Lauren Oberlin, Lindsay Arader, Merete Chaplin, Samprit Banerjee, George S. Alexopoulos Tags: Regular Research Article Source Type: research

Dimensions of Poststroke Depression and Neuropsychological Deficits in Older Adults
Stroke is the leading cause of both serious and long-term disability and the fifth leading cause of death in the United States.1,2 Poststroke depression (PSD) afflicts approximately one-fourth of stroke survivors and increases the likelihood of persistent disability.3 –6 Prompt identification and treatment of PSD can improve affective symptoms and stroke related disability.7,8
Source: The American Journal of Geriatric Psychiatry - January 24, 2020 Category: Geriatrics Authors: Dora Kanellopoulos, Victoria Wilkins, Jimmy Avari, Lauren Oberlin, Lindsay Arader, Merete Chaplin, Samprit Banerjee, George S. Alexopoulos Tags: Regular Research Article Source Type: research

The Prevalence and Factors Associated with Antiepileptic Drug Use in US Nursing Home Residents
ConclusionsAED use was common in nursing homes, with gabapentin most commonly used (presumably for pain). That multiple comorbidities were associated with AED use underscores the need for future studies to investigate the safety and effectiveness of AED use in nursing home residents.
Source: Drugs and Aging - December 15, 2019 Category: Geriatrics Source Type: research

Direct electrophysiological evidence that spreading depolarization-induced spreading depression is the pathophysiological correlate of the migraine aura and a review of the spreading depolarization continuum of acute neuronal mass injury
AbstractSpreading depolarization is observed as a large negative shift of the direct current potential, swelling of neuronal somas, and dendritic beading in the brain ’s gray matter and represents a state of a potentially reversible mass injury. Its hallmark is the abrupt, massive ion translocation between intraneuronal and extracellular compartment that causes water uptake (= cytotoxic edema) and massive glutamate release. Dependent on the tissue’s energy st atus, spreading depolarization can co-occur with different depression or silencing patterns of spontaneous activity. In adequately supplied tissue, spreading depo...
Source: AGE - December 8, 2019 Category: Geriatrics Source Type: research

Transitions to family caregiving: enrolling incident caregivers and matched non-caregiving controls from a population-based study.
CONCLUSION: Comparable, population-based samples of incident caregivers and matched non-caregivers have been enrolled. Future analyses will examine within-person changes in health and circulating biomarkers as a function of the transition to caregiving. PMID: 31630377 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - October 18, 2019 Category: Geriatrics Authors: Roth DL, Haley WE, David Rhodes J, Sheehan OC, Huang J, Blinka MD, Yuan Y, Irvin MR, Jenny N, Durda P, Cushman M, Walston JD, Howard VJ Tags: Aging Clin Exp Res Source Type: research

308 Association of Diabetes and Frailty with Mortality in Middle-Aged and Older Europeans
ConclusionFrailty and pre-frailty are independent risk factors for mortality in diabetics. The identification of frailty is important for the risk-stratification and management of middle aged and older patients with diabetes and should be included in the routine assessment of these high-risk individuals.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

Comparison of the risk for dementia between physicians and the general population: a nationwide population-based cohort study.
CONCLUSIONS: Physicians had a lower prevalence for dementia than the general population. The prevalence for dementia in specific subgroups of physicians was higher, which needs to be clarified by further studies. PMID: 31428999 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - August 18, 2019 Category: Geriatrics Authors: Ma LJ, Wu TM, Feng IJ, Hsu CC, Su SB, Wang JJ, Huang CC Tags: Aging Clin Exp Res Source Type: research

Predictors of Quality of Life among Older People with Mild Cognitive Impairment Attending Urban Primary Care Clinics.
CONCLUSIONS: MCI was prevalent among study participants and were associated with poorer QOL in all domains of QOL. A better understanding of predictors of QOL in older people with MCI is deemed important. CLINICAL IMPLICATION: Routine cognitive screening at primary care clinics will facilitate early recognition of MCI and facilitates referral to memory clinics for further assessment and treatment. PMID: 31107185 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - May 21, 2019 Category: Geriatrics Tags: Clin Gerontol Source Type: research

Gender differences in presentation of behavioral and psychological symptoms in Alzheimer's disease in Taiwan.
CONCLUSIONS: The presentation of delusion and disinhibition in BPSD is associated with the female gender and staging of AD. Disinhibition was not necessarily associated with late stage of AD. PMID: 30912669 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - March 25, 2019 Category: Geriatrics Authors: Hsieh SW, Chen CH, Huang LC, Chang YH, Yang YH Tags: Aging Ment Health Source Type: research

Atorvastatin in the treatment of lithium-induced nephrogenic diabetes insipidus: the protocol of a randomized controlled trial
Lithium is the gold-standard treatment for bipolar disorder, is highly effective in major depressive disorder, and is being investigated for therapeutic benefits in dementia, stroke, and even cancer. Approximately 350,000 Canadians use lithium and more could benefit. Despite this, clinicians are avoiding lithium, largely due to fear of renal toxicity, including irreversible chronic kidney disease (CKD). Nephrogenic Diabetes Insipidus (NDI) occurs in 20% of lithium users and independently predicts a 2-3 times increased risk of CKD.
Source: The American Journal of Geriatric Psychiatry - February 28, 2019 Category: Geriatrics Authors: Jocelyn Fotso Soh, Gabriela Torres-Platas, Serge Beaulieu, Outi Mantere, Robert Platt, Istvan Mucsi, Sybille Saury, Suzane Renaud, Andrea Levinson, Ana Andreazza, Benoit Mulsant, Daniel Mueller, Ayal Schaffer, Annemiek Dols, Nancy Low, Pablo Cervantes, Na Tags: Poster Number: EI - 48 Source Type: research

Depressive symptoms across the age span: findings from an integrated epilepsy self-management clinical studies dataset.
Epilepsy has been reported by the CDC to have a prevalence of 1.2% in the United States, which accounts for roughly 3.4 million adults in 2015. Nearly 1 million of those adults are aged 55 or older.1 Epilepsy is more likely to develop in older adults because risk factors for epilepsy are more common as people age including stroke/cardiovascular disease, neurodegenerative disorders, brain tumor and long-term sequelae of alcohol abuse.2 As our population ages, there will be even more older people with epilepsy.
Source: The American Journal of Geriatric Psychiatry - February 28, 2019 Category: Geriatrics Authors: Zaira Khalid, Hasina Momotaz, Kristen Cassidy, Naomi Chaytor, Robert Fraser, Mary Janevic, Barbara Jobst, Erica Johnson, Peter Scal, Tanya Spruill, Martha Sajatovic Tags: Poster Number: EI - 9 Source Type: research

The relationship between discharge medications and falls in post-hospitalised older adults: A 6-month follow-up.
CONCLUSION: Falls prevention strategies, other than hospital discharge medication management in the postdischarge older adults, warrant investigation. PMID: 30806033 [PubMed - as supplied by publisher]
Source: Australasian Journal on Ageing - February 25, 2019 Category: Geriatrics Authors: Lam K, Lee DA, Lalor AF, Stolwyk R, Russell G, Brown T, McDermott F, Haines TP Tags: Australas J Ageing Source Type: research

Effects of Tai Chi Yunshou exercise on community-based stroke patients: a cluster randomized controlled trial
ConclusionTai Chi Yunshou and balance rehabilitation training led to improved balance ability and functional mobility, and both are suitable community-based programs that may benefit for stroke recovery and community reintegration. Our data demonstrated that a 12-week Tai Chi Yunshou intervention was more effective in motor function, fear of falling and depression than balance rehabilitation training. Future studies examining the effectiveness of Tai Chi Yunahou as a balance ability improvement strategy for community-dwelling survivors of stroke are recommended.Trial registrationChinese Clinical Trail Registry:ChiCRT-TRC-1...
Source: European Review of Aging and Physical Activity - December 12, 2018 Category: Geriatrics Source Type: research

Mild Cognitive Impairment that Does Not Progress to Dementia: A Population ‐Based Study
ConclusionsMCI subgroups with different 5 ‐year outcomes had some distinct characteristics suggesting different underlying causes. The progressors, unlike the reverters, had a profile broadly typical of Alzheimer's disease; the stable MCIs had other, including vascular, morbidity. These data shed light on the heterogeneity of MCI in the p opulation.
Source: Journal of the American Geriatrics Society - November 16, 2018 Category: Geriatrics Authors: Mary Ganguli, Yichen Jia, Tiffany F. Hughes, Beth E. Snitz, Chung ‐Chou H. Chang, Sarah B. Berman, Kevin J. Sullivan, M. Ilyas Kamboh Tags: Clinical Investigation Source Type: research