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Condition: Depression
Management: National Institutes of Health (NIH)

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Total 57 results found since Jan 2013.

Predictors of early-onset depression after first-ever stroke.
PREDICTORS OF EARLY-ONSET DEPRESSION AFTER FIRST-EVER STROKE. Acta Clin Croat. 2020 Mar;59(1):81-90 Authors: Rabi-Žikić T, Živanović Ž, Đajić V, Simić S, Ružička-Kaloci S, Slankamenac S, Žikić M Abstract Post-stroke depression (PSD) is a severe and frequent stroke complication and one of the crucial factors for the outcome of rehabilitation and life quality after stroke. However, mood disorders frequently remain unnoticed and therefore untreated. The aim of the study was to examine all the potential risk factors and determine the independent predictors of early-onset depression after first-...
Source: Acta Clinica Croatica - July 31, 2020 Category: General Medicine Tags: Acta Clin Croat Source Type: research

miR-22 and cerebral microbleeds in brainstem and deep area are associated with depression one month after ischemic stroke.
In this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever and recurrent acute cerebral infarction and performed PSD diagnosis in accordance with the Diagnostic and Statistical Manual IV criteria for depression. Clinical information, assessments of stroke severity, and imaging data were recorded on admission. We further detected plasma miR-22 using quantitative PCR and analyzed the relationship among miR-22, clinical data, and PSD using SPSS 23.0 software. Logistic...
Source: Braz J Med Biol Res - April 30, 2020 Category: Research Authors: Hu J, Zhou W, Zhou Z, Yang Q, Xu J, Dong W Tags: Braz J Med Biol Res Source Type: research

Functional recovery after ischemic stroke: Impact of different sleep health parameters
J Sleep Res. 2023 Jun 20:e13964. doi: 10.1111/jsr.13964. Online ahead of print.ABSTRACTSleep disturbances after ischaemic stroke include alterations of sleep architecture, obstructive sleep apnea, restless legs syndrome, daytime sleepiness and insomnia. Our aim was to explore their impacts on functional outcomes at month 3 after stroke, and to assess the benefit of continuous positive airway pressure in patients with severe obstructive sleep apnea. Ninety patients with supra-tentorial ischaemic stroke underwent clinical screening for sleep disorders and polysomnography at day 15 ± 4 after stroke in a multisite study. Pati...
Source: Journal of Sleep Research - June 20, 2023 Category: Sleep Medicine Authors: Claire Denis Isabelle Jaussent Lily Guiraud Caroline Mestejanot Caroline Arquizan Isabelle Mourand Sofi ène Chenini Beatriz Abril Anne Wacongne Renaud Tamisier S ébastien Baillieul Jean-Louis Pepin Lucie Barateau Yves Dauvilliers Source Type: research

Apathy and suicide-related ideation 3 months after stroke: a cross-sectional study
Background: Both apathy and suicide are common in poststroke patients. However, the association between poststroke apathy and suicide-related ideation (SI) in Chinese stroke patients is not clear and poorly understood. The aim of this study was to examine the association between apathy and SI in stroke. Methods: A cross-sectional study was conducted to investigate the association in 518 stroke survivors from Acute Stroke Unit of the Prince of Wales Hospital in Hong Kong. Geriatric Mental State Examination-Version A (GMS) and Neuropsychiatric Inventory-apathy subscale (NPI-apathy) were employed to assess poststroke SI and a...
Source: BMC Neurology - April 23, 2015 Category: Neurology Authors: Wai TangLara CaeiroChieh LauHuajun LiangVincent MokGabor UngvariKa Wong Source Type: research

Psychopathological evaluation and use of the Hospital Anxiety and Depression Scale in a sample of Brazilian patients with post-stroke depression
This study aimed to characterize psychopathological aspects of Brazilian patients admitted to an acute stroke unit, and to evaluate the performance of the Hospital Anxiety and Depression Scale (HADS) in detecting cases of depression. Methods: This was a cross-sectional study. Sixty consecutive patients admitted to an acute stroke unit were assessed with the National Institutes of Health Stroke Scale, the Modified Rankin Scale, the Functional Independence Measure, the Mini International Neuropsychiatric Interview-Plus, the HADS, the Mini Mental State Examination (MMSE) and the Pathological Laughing and Crying Scale. Results...
Source: Revista de Psiquiatria Clinica - December 12, 2016 Category: Psychiatry Source Type: research

Efficacy of sequential N-butylphthalide therapy on psychiatric and behavioral functions in acute ischemic stroke
This study examined how the sequential therapy of N-butylphthalide (NBP) could effectively improve physical movement, life activities, and psychological disorders in stroke patients. Methods: This double-blind, randomized controlled trial included middle-aged or elderly patients with acute ischemic stroke that had commenced within 48 hours before enrolment in the study. The experimental group was administered 100 mL NBP injections twice a day in the first 14 days, and a sequential 200 mg NBP soft capsule 3 times a day for the next 76 days. The control group was administered 100 mL NBP placebo injections ...
Source: Medicine - November 19, 2021 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Gothenburg very early supported discharge study (GOTVED) NCT01622205: a block randomized trial with superiority design of very early supported discharge for patients with stroke
Background: Stroke is the disease with the highest costs for hospital care and also after discharge. Early supported discharge (ESD) has shown to be efficient and safe and the best results with well-organised discharge teams and patients with less severe strokes.The aim is to investigate if very early supported discharge (VESD) for stroke patients in need for on-going individualised rehabilitation at home is useful for the patient and cost effective. Methods: A randomized controlled trial comparing VESD with ordinary discharge. Inclusion criteria: confirmed stroke,>18 years of age, living within 30 min from the stroke unit...
Source: BMC Neurology - June 24, 2013 Category: Neurology Authors: Katharina SunnerhagenAnna DanielssonRafsten LenaAnn BjörkdahlÅsa AxelssonÅsa NordinCathrine PeterssonÅsa Lundgren-NilssonFröjd Karin Source Type: research

Elevated Serum Levels of Neopterin at Admission Predicts Depression After Acute Ischemic Stroke: a 6-Month Follow-Up Study
Abstract Inflammation and cell-mediated immune activation are attributed to the pathogenesis and pathophysiology in depression. Our aim was to test the possible association between serum levels of neopterin and the development of post-stroke depression (PSD) in Chinese patients. The subjects were first-ever acute ischemic stroke patients who were hospitalized at the First Affiliated Hospital of Xinxiang Medical University during the period from December 2012 to December 2013. Clinical information and stroke severity were collected at admission. Neurological and neuropsychological evaluations were conducted at the ...
Source: Molecular Neurobiology - June 4, 2015 Category: Neurology Source Type: research

Clinical efficacy of Danzhi Xiaoyao Powder in the treatment of post-stroke depression: A protocol for randomized, double-blind clinical study
This study will evaluate the clinical efficacy of Danzhi Xiaoyao Powder in the treatment of PSD. The results of this study will provide reliable evidence for the clinical use of Xiaoyao Powder in the treatment of PSD. Trial registration: Open Science Framework Registration number: DOI 10.17605/OSF.IO/5V926
Source: Medicine - October 22, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Integrative medicine for subacute stroke rehabilitation: a study protocol for a multicentre, randomised, controlled trial
Introduction Many patients with stroke receive integrative medicine in China, which includes the basic treatment of Western medicine and routine rehabilitation, in conjunction with acupuncture and Chinese medicine. The question of whether integrative medicine is efficacious for stroke rehabilitation is still controversial and very little research currently exists on the integrated approach for this condition. Consequently, we will conduct a multicentre, randomised, controlled, assessor-blinded clinical trial to assess the effectiveness of integrative medicine on stroke rehabilitation. Methods and analysis 360 participants...
Source: BMJ Open - December 4, 2014 Category: Journals (General) Authors: Fang, J., Chen, L., Chen, L., Wang, C., Keeler, C. L., Ma, R., Xu, S., Shen, L., Bao, Y., Ji, C. Tags: Open access, Complementary medicine Protocol Source Type: research

Association of post stroke depression with social factors, insomnia, and neurological status in Chinese elderly population
Abstract The purpose of this study was to investigate the association of post stroke depression (PSD) with social factors, insomnia, and neurological status among elderly Chinese patients with ischemic stroke. Six hundred and eight patients over 60 years of age, who had suffered from a first episode of ischemic stroke within 7 days, were enrolled into the study. They were divided into PSD and non-PSD groups according to the Self-rating Depression Scale (SDS) scores. The association of PSD with social factors, insomnia, and neurological status was analyzed using multivariable logistic regression analysis. Compare...
Source: Neurological Sciences - April 26, 2016 Category: Neurology Source Type: research

Changes and predictors of psychological stress among elderly stroke survivors 6  months after hospital discharge
Abstract The aim of this study was to analyse the changes in psychological stress and identify its basal predictors among elderly stroke survivors after 6 months following discharge from hospital to home directly, rather than to a rehabilitation facility. The sample comprised 50 elderly stroke survivors. Data were collected at 2 weeks (T1), at 3 months (T2), and at 6 months (T3) after hospital discharge. The following instruments were applied: Perceived Stress Scale—10 items (PSS‐10), National Institute of Health Stroke Scale, Functional Independence Measure, and Geriatric Depression Scale—15 items. Study records...
Source: Stress and Health - December 1, 2017 Category: Psychiatry & Psychology Authors: Emanuella Barros Santos, Rosalina Aparecida Partezani Rodrigues, Jack Roberto Silva Fhon, Vanderlei Jos é Haas Tags: RESEARCH ARTICLE Source Type: research

Erectile dysfunction and associated risk factors in male patients with ischemic stroke: A cross-sectional study
This study aimed to investigate the incidence of ED, sexual quality of life, and mental state of patients after stroke, as well as analyze the relevant risk factors affecting their psychological status. A total of 361 IS patients were enrolled. The international erectile function index-5 scale was used to diagnose ED. Accordingly, the patients were divided into ED group and non-ED group. Magnetic resonance imaging was used to evaluate the brain lesions of patients. We assessed neurological deficits by the National Institutes of Health Stroke Scale score and patient health questionnaire-9 (PHQ-9) and general anxiety disord...
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research