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Ischemic stroke in liver cirrhosis: epidemiology, risk factors, and in-hospital outcomes
Conclusion Ischemic stroke was often observed in patients with cirrhosis, and it significantly increased the in-hospital mortality. The association of inflammation, coagulation disorders, and viral hepatitis with development of ischemic stroke in liver cirrhosis should be further evaluated in prospective cohort studies.
Source: European Journal of Gastroenterology and Hepatology - December 22, 2017 Category: Gastroenterology Tags: Original Articles: Liver Cirrhosis Source Type: research

Risk of Stroke in Liver Cirrhosis: A Systematic Review and Meta-Analysis
Conclusions: Stroke is uncommon in cirrhotic patients. However, considering a positive relationship of liver cirrhosis with subarachnoid and intracranial hemorrhage, the prophylactic strategy may be selectively adopted in cirrhotic patients.
Source: Journal of Clinical Gastroenterology - December 7, 2019 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Risk score to predict gastrointestinal bleeding after acute ischemic stroke
Conclusion: The AIS-GIB score is a valid clinical grading scale to predict in-hospital GIB after AIS. Further studies on the effect of the AIS-GIB score on reducing GIB and improving outcome after AIS are warranted.
Source: BMC Gastroenterology - July 25, 2014 Category: Gastroenterology Authors: Ruijun JiHaipeng ShenYuesong PanPenglian WangGaifen LiuYilong WangHao LiAneesh SinghalYongjun Wang Source Type: research

Clinical features in liver cirrhosis patients who have experienced ischemic stroke.
CONCLUSION: Our results show that a comparatively high frequency of ischemic stroke occurs in patients with alcohol-induced liver cirrhosis and in patients with a less compromised liver function. In addition, it was found that most patients possessed at least one risk factor of ischemic stroke. PMID: 25599784 [PubMed - in process]
Source: The Turkish Journal of Gastroenterology - December 1, 2014 Category: Gastroenterology Authors: Kim KM, Hwang JW, Shim SG Tags: Turk J Gastroenterol Source Type: research

Is cirrhosis associated with lower odds of ischemic stroke: A nationwide analysis?
CONCLUSION: Our study suggests that in a large, nationally representative sample of the United States population, cirrhosis is associated with a lower likelihood of stroke. PMID: 28050237 [PubMed]
Source: World Journal of Hepatology - January 6, 2017 Category: Gastroenterology Tags: World J Hepatol Source Type: research

Predictors of inadequate bowel preparation for colonoscopy: a systematic review and meta-analysis
The aim of this study was to investigate factors contributing to poor bowel preparation in patients undergoing colonoscopy procedures. We used a reproducible search strategy to identify studies, searching 10 medical databases, including PubMed, Ovid, Medline, and Cochrane Library Database for reports published between 2000 and 2016. Fully published studies, evaluating risk factors for inadequate bowel preparation, were included. Two reviewers independently scored the identified studies for methodology and abstracted pertinent data. Pooling was conducted with both fixed-effects and random-effects models; results were presen...
Source: European Journal of Gastroenterology and Hepatology - July 6, 2018 Category: Gastroenterology Tags: Review Articles: Gastroenterology Source Type: research

Non-alcoholic fatty liver disease and incident major adverse cardiovascular events: results from a nationwide histology cohort
Conclusion Compared with matched population controls, patients with biopsy-proven NAFLD had significantly higher incidence of MACE, including IHD, stroke, CHF and CV mortality. Excess risk was evident across all stages of NAFLD and increased with worsening disease severity.
Source: Gut - August 11, 2022 Category: Gastroenterology Authors: Simon, T. G., Roelstraete, B., Hagström, H., Sundström, J., Ludvigsson, J. F. Tags: Gut Hepatology Source Type: research

Reduced thoracic fluid content in early-stage primary biliary cirrhosis that associates with impaired cardiac inotropy
This study has confirmed that TFC is reduced in those with PBC, that this is specific to PBC, and that it associates independently with markers of cardiac inotropy.
Source: AJP: Gastrointestinal and Liver Physiology - September 15, 2013 Category: Gastroenterology Authors: Zalewski, P., Jones, D., Lewis, I., Frith, J., Newton, J. L. Tags: CALL FOR PAPERS Source Type: research

β-Blocker therapy for cirrhotic cardiomyopathy: a randomized-controlled trial
Background Cirrhotic cardiomyopathy is characterized by an attenuated contractile response to stress. Long-term exposure of β-adrenergic receptors to persistently high levels of catecholamines has been implicated in its pathogenesis. We hypothesized that β-blockade with metoprolol could reverse the changes in heart function and morphology in cirrhotic cardiomyopathy. Patients and methods In this prospective randomized trial, we included 78 patients aged between 18 and 60 years with abnormal cardiac output response under dobutamine stress echocardiography, without primary cardiac disease or a history of alcohol intak...
Source: European Journal of Gastroenterology and Hepatology - July 6, 2018 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Reduced thoracic fluid content in early stage primary biliary cirrhosis that associates with impaired cardiac inotropy.
Conclusion: This study has confirmed that TFC is reduced in those with PBC, that this is specific to PBC and that it associates independently with markers of cardiac inotropy. PMID: 23868409 [PubMed - as supplied by publisher]
Source: Am J Physiol Gastroi... - July 18, 2013 Category: Gastroenterology Authors: Zalewski P, Jones DE, Lewis I, Frith J, Newton JL Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research

Impact of Renal Impairment on Cardiovascular Disease Mortality After Liver Transplantation for Nonalcoholic Steatohepatitis Cirrhosis
ConclusionNASH recipients have an increased risk of CVD mortality after liver transplantation explained by a high prevalence of co‐morbid cardiometabolic risk factors that in aggregate identify those at highest risk of post‐transplant CVD mortality.This article is protected by copyright. All rights reserved.
Source: Liver International - May 15, 2015 Category: Gastroenterology Authors: Lisa B. VanWagner, Brittany Lapin, Anton I. Skaro, Donald M. Lloyd‐Jones, Mary E. Rinella Tags: Original Article Source Type: research

Diabetics on Narcotics Are Less Likely to Achieve Excellent Bowel Preparation Than Are Patients with Either Condition
ConclusionConcomitant narcotic use and diabetes have a compounding effect on the quality of bowel preparation prior to colonoscopy.
Source: Digestive Diseases and Sciences - December 28, 2016 Category: Gastroenterology Source Type: research

Cirrhosis Tied to Increased Stroke Risk (CME/CE)
(MedPage Today) -- Strongest association seen with subarachnoid and intracerebral hemorrhage
Source: MedPage Today Gastroenterology - June 6, 2017 Category: Gastroenterology Source Type: news

New predictive model for acute gastrointestinal bleeding in patients taking oral anticoagulants: A cohort study
ConclusionsGastrointestinal bleeding increased the risk of subsequent mortality during follow‐up of anticoagulated patients, highlighting the importance of prevention. The study developed a new scoring model for acute GI bleeding risk based on five factors (no‐proton pump inhibitor use, chronic kidney disease, chronic obstructive pulmonary disease, history of peptic ulcer disease, and liver cirrhosis), which was superior to the HAS‐BLED score.
Source: Journal of Gastroenterology and Hepatology - December 28, 2017 Category: Gastroenterology Authors: Akira Shimomura, Naoyoshi Nagata, Takuro Shimbo, Toshiyuki Sakurai, Shiori Moriyasu, Hidetaka Okubo, Kazuhiro Watanabe, Chizu Yokoi, Junichi Akiyama, Naomi Uemura Tags: Gastroenterology Source Type: research

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