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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Management of Hyperlipidemia After Stroke
AbstractPurpose of reviewHyperlipidemia is a key therapeutic target for stroke risk modification. The goal of this review is to highlight available treatment options and review their efficacy in the setting of general cardiovascular disease and after most subtypes of ischemic stroke and hemorrhagic stroke.Recent findingsStatins remain first-line in the management of hyperlipidemia to prevent stroke. In recent trials of patients with pre-existing atherosclerotic vascular disease, new agents, most notably PCSK9 inhibitors and ezetimibe, added additional stroke risk reduction when combined with statins.SummaryRisk of stroke c...
Source: Current Treatment Options in Cardiovascular Medicine - December 15, 2019 Category: Cardiology Source Type: research

Mildly Abnormal Lipid Levels, but Not High Lipid Variability, Are Associated with Increased Risk of Myocardial Infarction and Stroke in 'Statin-Naive' Young Population: A Nationwide Cohort Study.
Conclusions: Mildly abnormal baseline lipid levels were associated with an increased future risk of ASCVD events, particularly MI, whereas measures of lipid variability were not. Therefore, in young adults, achieving optimal lipid levels could be valuable in the prevention of ASCVD. PMID: 31978313 [PubMed - as supplied by publisher]
Source: Circulation Research - January 23, 2020 Category: Cardiology Authors: Park JB, Kim D, Lee H, Hwang IC, Yoon YE, Park HE, Choi SY, Kim YJ, Cho GY, Han KD, Kim HK Tags: Circ Res Source Type: research

Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association.
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, healthcare administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions. PMID: 31992061 [PubMed - as supplied by publisher]
Source: Circulation - January 28, 2020 Category: Cardiology Authors: Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longeneck Tags: Circulation Source Type: research

Atrial Fibrillation With and Without Cardiovascular Risk Factors and Stroke Mortality.
CONCLUSIONS: AF was found to be an independent risk factor for stroke and total cardiovascular mortality even in individuals without other TCVRFs. PMID: 32554949 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - June 20, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions. PMID: 33501848 [PubMed - as supplied by publisher]
Source: Circulation - January 27, 2021 Category: Cardiology Authors: Virani SS, Alonso A, Aparicio HJ, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Cheng S, Delling FN, Elkind MSV, Evenson KR, Ferguson JF, Gupta DK, Khan SS, Kissela BM, Knutson KL, Lee CD, Lewis TT, Liu J, Loop MS, Lutsey PL, Ma J, Tags: Circulation Source Type: research

Long-term risk of stroke and myocardial infarction in middle-aged men with a hypertensive response to exercise: a 44-year follow-up study
Conclusion: Among middle-aged men with high resting and maximum blood pressure during maximum exercise workload, an increased risk of stroke was observed but not for MI. Further studies with larger sample sizes are needed to investigate the underlying mechanisms of the increased risk of stroke among individuals with hypertensive response to exercise.
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?
J Stroke. 2022 Jan;24(1):21-40. doi: 10.5853/jos.2021.02831. Epub 2022 Jan 31.ABSTRACTHypertriglyceridemia is caused by defects in triglyceride metabolism and generally manifests as abnormally high plasma triglyceride levels. Although the role of hypertriglyceridemia may not draw as much attention as that of plasma cholesterol in stroke, plasma triglycerides, especially nonfasting triglycerides, are thought to be correlated with the risk of ischemic stroke. Hypertriglyceridemia may increase the risk of ischemic stroke by promoting atherosclerosis and thrombosis and increasing blood viscosity. Moreover, hypertriglyceridemia...
Source: Atherosclerosis - February 8, 2022 Category: Cardiology Authors: Hai-Jie Liang Qing-Yi Zhang Yi-Tong Hu Guo-Qing Liu Rong Qi Source Type: research

Nontraditional Risk Factors for Residual Recurrence Risk in Patients with Ischemic Stroke of Different Etiologies
CONCLUSIONS: LAA and SAO subtypes own the specific nontraditional risk factors while inflammation is a common risk factor for residual recurrence risk of both.PMID:35390802 | DOI:10.1159/000523919
Source: Atherosclerosis - April 7, 2022 Category: Cardiology Authors: Jie Xu Jinglin Mo Xing Zhang Zimo Chen Yuesong Pan Hongyi Yan Xia Meng Yongjun Wang Source Type: research

Diffusion-weighted imaging-based radiomics for predicting 1-year ischemic stroke recurrence
CONCLUSION: DWI-based radiomics could help to predict 1-year ischemic stroke recurrence.PMID:36388230 | PMC:PMC9649925 | DOI:10.3389/fneur.2022.1012896
Source: Atherosclerosis - November 17, 2022 Category: Cardiology Authors: Hao Wang Yi Sun Jie Zhu Yuzhong Zhuang Bin Song Source Type: research

Lipid profiles and atrial fibrillation in ischemic stroke patients treated with thrombectomy: experience from a tertiary Italian stroke hospital
CONCLUSION: Total cholesterol and all cholesterol-related measures were significantly lower in patients undergoing thrombectomy than in other stroke patients. Conversely, we found that AF was significantly high in patients with EVT, suggesting that hypercholesterolemia could be mainly linked to small-vessel occlusion stroke while large vessel occlusion (LVO) stroke could show different causes. AIS patients may have different pathogenesis and their understanding may improve enhance the discovery of specific and tailored preventive treatments.PMID:37221691 | DOI:10.2174/1871525721666230522124351
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - May 24, 2023 Category: Cardiology Authors: Maria Cristina Bravi Fabio Pilato Domenica Crupi Marilena Mangiardi Francesca Romana Pezzella Antonio Siniscalchi Enrico Cotroneo Luca Bertaccini Michele Alessiani Sabrina Anticoli Source Type: research

ABI and stroke: Action at a distance and a call to action
Stroke is a catastrophic clinical event and is justifiably feared by both patients and physicians alike. Given the aging demographic of western populations, the morbid consequences of stroke are also a growing burden on healthcare resources . For example, projections show that by 2030 an additional 3.4 million US adults will have suffered a stroke, a 20.5% increase in prevalence from 2012 . The majority of strokes are ischemic and a consequence of either thromboembolism or atherosclerosis or both. Fortunately, effective primary prevention therapies exist, including aspirin and statins , which can reduce the risk of ischemi...
Source: Atherosclerosis - April 10, 2014 Category: Cardiology Authors: John W. McEvoy, Khurram Nasir Tags: Invited Commentaries Source Type: research

Blood Pressure, Low-Density Lipoprotein Cholesterol, and Incidences of Coronary Artery Disease and Ischemic Stroke in Japanese: The Suita Study.
CONCLUSIONS: The HRs for CAD in prehypertensive and hypertensive groups were higher than those in the optimal BP group at the same LDL-C levels in a Japanese population; however, there was no statistical effect modification of LDL-C on the BP-CAD association. PMID: 24713850 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - April 8, 2014 Category: Cardiology Authors: Tsukinoki R, Okamura T, Watanabe M, Kokubo Y, Higashiyama A, Nishimura K, Takegami M, Murakami Y, Okayama A, Miyamoto Y Tags: Am J Hypertens Source Type: research

Intracranial Hemorrhage After Ischemic Stroke: Incidence, Time Trends, and Predictors in a Swedish Nationwide Cohort of 196 765 Patients Original Articles
Conclusions— The incidence of ICrH within 1 year after ischemic stroke was 2% per year at risk, about 15 times higher compared with the reference population. Over the study period, ICrH risk increased within the first 30 days but decreased thereafter. Previous ICrH, thrombolysis, and male sex affected the risk, whereas an increased use of antithrombotic treatments and statins did not.
Source: Circulation: Cardiovascular Quality and Outcomes - July 21, 2015 Category: Cardiology Authors: Ogren, J., Irewall, A.-L., Bergstrom, L., Mooe, T. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Epidemiology Original Articles Source Type: research