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Total 249 results found since Jan 2013.

N-Terminal Pro-B-type Natriuretic Peptide and Stroke Risk: The Reasons for Geographic and Racial Differences in Stroke Cohort Clinical Sciences
Conclusions— NT-proBNP was a major independent risk marker for stroke. Considering this and other data for stroke, coronary disease, and atrial fibrillation, the clinical use of NT-proBNP measurement in primary prevention settings should be considered.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Cushman, M., Judd, S. E., Howard, V. J., Kissela, B., Gutierrez, O. M., Jenny, N. S., Ahmed, A., Thacker, E. L., Zakai, N. A. Tags: Acute Cerebral Infarction, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

Guideline-Directed Low-Density Lipoprotein Management in High-Risk Patients With Ischemic Stroke: Findings From Get With The Guidelines-Stroke 2003 to 2012 Clinical Sciences
Conclusions— Management of dyslipidemia in high-risk patients with preexistent CAD or stroke continues to be suboptimal. Only 1 in 5 patients with prior TIA/stroke had LDL levels <70 mg/dL.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Saposnik, G., Fonarow, G. C., Pan, W., Liang, L., Hernandez, A. F., Schwamm, L. H., Smith, E. E., on behalf of the AHA Get-with-the-Guidelines Stroke Tags: Secondary prevention, Acute Cerebral Infarction, Lipid and lipoprotein metabolism Clinical Sciences Source Type: research

Ideal Cardiovascular Health Metrics and the Risks of Ischemic and Intracerebral Hemorrhagic Stroke Clinical Sciences
Conclusions— We observed a clear inverse gradient relationship between the number of ideal CVH metrics and the risk of stroke in a Chinese population, supporting the importance of ideal health behaviors and factors in stroke prevention.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Zhang, Q., Zhou, Y., Gao, X., Wang, C., Zhang, S., Wang, A., Li, N., Bian, L., Wu, J., Jia, Q., Wu, S., Zhao, X. Tags: Cerebrovascular disease/stroke, Epidemiology Clinical Sciences Source Type: research

Community-Based Intervention to Improve Cardiometabolic Targets in Patients With Stroke Clinical Sciences
Conclusions—The intervention in this largely negative trial only had a detectable effect on attaining target for lipids but not for other factors at 12 months or any factor at 24 months. This limited effect may be attributable to inadequate uptake of behavioral/lifestyle interventions, highlighting the need for new or better approaches to achieve meaningful behavioral change.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: ACTRN12608000166370.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Muideen T. Olaiya, Dominique A. Cadilhac, Joosup Kim, Mark R. Nelson, Velandai K. Srikanth, Richard P. Gerraty, Christopher F. Bladin, Sharyn M. Fitzgerald, Thanh Phan, Judith Frayne, Amanda G. Thrift Tags: Lifestyle, Risk Factors, Secondary Prevention, Treatment, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Risk of Metabolic Syndrome for Stroke Is Not Greater than the Sum of its Components: Thai Epidemiologic Stroke (TES) Study
This study aimed to assess the association of MetS with stroke, and to evaluate whether the risk of MetS is greater than the sum of its components. The Thai Epidemiologic Stroke (TES) study is a community-based cohort study with 19,997 participants, aged 45-80 years, recruited from the general population from 5 regions of Thailand. Baseline survey data were analyzed in cross-sectional analyses. MetS was defined according to criteria from the National Cholesterol Education Program (NCEP) Adult Treatment Panel III, the American Heart Association/National Heart, Lung, and Blood Institute (revised NCEP), and International Diab...
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2012 Category: Neurology Authors: Suchat Hanchaiphiboolkul, Nijasri Charnnarong Suwanwela, Niphon Poungvarin, Samart Nidhinandana, Pimchanok Puthkhao, Somchai Towanabut, Tasanee Tantirittisak, Jithanorm Suwantamee, Maiyadhaj Samsen Tags: Original Articles Source Type: research

Effect of Peer Education on Stroke Prevention: The Prevent Recurrence of All Inner-City Strokes Through Education Randomized Controlled Trial Clinical Sciences
Conclusions— A low-cost peer education self-management workshop modestly improved blood pressure, but not low-density lipoprotein cholesterol or antithrombotic use, among stroke and transient ischemic attack survivors from vulnerable, predominantly minority urban communities. Clinical Trial Registration— URL: http://www.clinicaltrials.gov/show/NCT0102727. Unique identifier: NCT01027273.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Kronish, I. M., Goldfinger, J. Z., Negron, R., Fei, K., Tuhrim, S., Arniella, G., Horowitz, C. R. Tags: Compliance/Adherence, Secondary prevention Clinical Sciences Source Type: research

Implementation of a Structured Guideline-Based Program for the Secondary Prevention of Ischemic Stroke in China Clinical Sciences
Conclusions— The implementation of a program to improve adherence to secondary ischemic stroke prevention efforts in China is feasible, but these programs had only a limited impact on adherence and no impact on 1-year outcomes. Further development of a structured program to reduce vascular events after stroke is needed. Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00664846.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Peng, B., Ni, J., Anderson, C. S., Zhu, Y., Wang, Y., Pu, C., Wu, J., Wang, J., Zhou, L., Yao, M., He, J., Shan, G., Gao, S., Xu, W., Cui, L., on behalf of the SMART Investigators Tags: Secondary prevention Clinical Sciences Source Type: research

Effects of Early Exercise Engagement on Vascular Risk in Patients with Transient Ischemic Attack and Nondisabling Stroke
The objective of this study was to conduct a randomized, parallel-group clinical trial assessed the efficacy of a health-enhancing physical activity program (exercise and education) on vascular risk factors and aerobic fitness in patients who have experienced a transient ischemic attack (TIA) or nondisabling stroke. Sixty patients (69 ± 11 years) completed a baseline (BL) vascular risk stratification and aerobic fitness examination (cycle test) within 2 weeks of symptom onset. Subjects were then randomized to either an 8-week, twice weekly exercise program or to a usual-care control (CON) group. Postintervention (PI) ...
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: James Faulkner, Danielle Lambrick, Brandon Woolley, Lee Stoner, Lai-kin Wong, Gerard McGonigal Tags: Original Articles Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

The Paradoxical Protective Effect of Liver Steatosis on Severity and Functional Outcome of Ischemic Stroke
Conclusions: Our study shows that a higher burden of liver steatosis seems to be associated with less severe stroke and better functional outcome after ischemic stroke or TIA. Introduction Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases from simple steatosis to steatohepatitis with varying degree of fibrosis, and liver cirrhosis (1, 2). NAFLD is becoming the most common chronic liver disease worldwide including Korea, affecting approximately 25% of the general population (3, 4). NAFLD is closely associated with obesity, insulin resistance, and type 2 diabetes mellitus, and is even recognized as ...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Memory gaps in graduates a 'stroke warning sign'
Conclusion This study showed that highly educated people who notice memory complaints in themselves may be more likely to develop stroke than those who don’t, over an average of 12 years. The study had a number of strengths, such as its population-based prospective design and availability of data on more than 9,000 participants at baseline with a long follow-up. However, there were also a number of limitations that weaken the strength of the conclusions. It was not clear whether the memory complaints were assessed just once at the start of the study or an ongoing basis. Some people may report memory complaints that are o...
Source: NHS News Feed - December 12, 2014 Category: Consumer Health News Tags: Neurology Mental health Older people Source Type: news

Longer sleep linked to stroke
Conclusion This cohort study found that, overall, people who sleep for more than eight hours have a 46% increased risk of stroke. When analysed separately, there was no statistically significant association for men, but a much higher increased risk for women, of 80%. A major strength of the study is the number of potential confounding factors that the researchers tried to account for, including many cardiovascular risk factors. However, it did not account for other illnesses such as sleep apnoea or cancer, which may have had an effect on the amount of sleep and risk of stroke. In addition, the study is reliant on the i...
Source: NHS News Feed - February 26, 2015 Category: Consumer Health News Tags: Lifestyle/exercise Neurology Older people Source Type: news

Reported link between diet drinks and dementia and stroke is weak
Conclusion The researchers used data from a large ongoing cohort study to look for links between consumption of sugary and artificially sweetened drinks and risk of stroke or dementia. This cohort study benefits from the large overall sample size, long period of data collection, careful and valid diagnostic assessments, and adjustments for a number of confounders. However, care must be taken when interpreting these results – particularly if latching on to the maximal tripled risk figures reported in the media. There are several points to consider: Small numbers The new number of strokes and dementia in this study was sma...
Source: NHS News Feed - April 21, 2017 Category: Consumer Health News Tags: Food/diet Heart/lungs Neurology Source Type: news