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Condition: Hyperactivity

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Total 310 results found since Jan 2013.

Predictors of externalizing behavior outcomes following pediatric stroke
This study included 210 children with pediatric ischemic stroke (mean age 9.18 years (SD = 3.95)). The parent form of the Behavioral Assessment System for Children-Second Edition (BASC-2) and Behavior Rating Inventory of Executive Function (BRIEF) were used to evaluate externalizing behavior and executive function. No externalizing behavior or executive function differences were found between perinatal (n = 94) or childhood (n = 116) stoke, except for the shift subscale which had higher T-scores among the perinatal group (M = 55.83) than childhood group (M = 50.40). When examined together, 10% of children had clinically el...
Source: Child Neuropsychology - March 9, 2023 Category: Child Development Authors: Alyssia Wilson Nataly Beribisky Mary Desrocher Nomazulu Dlamini Tricia Williams Robyn Westmacott Source Type: research

Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the kidneys.
Abstract Spontaneously hypertensive rats (SHRs) and stroke-prone SHRs (SHRSP) are frequently used as models not only of essential hypertension and stroke, but also of attention-deficit hyperactivity disorder (ADHD). Normotensive Wistar-Kyoto (WKY) rats are normally used as controls in these studies. In the present study, we aimed to identify the genes causing hypertension and stroke, as well as the genes involved in ADHD using these rats. We previously analyzed gene expression profiles in the adrenal glands and brain. Since the kidneys can directly influence the functions of the cardiovascular, endocrine and sy...
Source: International Journal of Molecular Medicine - July 10, 2015 Category: Molecular Biology Authors: Watanabe Y, Yoshida M, Yamanishi K, Yamamoto H, Okuzaki D, Nojima H, Yasunaga T, Okamura H, Matsunaga H, Yamanishi H Tags: Int J Mol Med Source Type: research

Enhanced activity of ADAMTS13 variant (R568K/F592Y/R660K/Y661F/Y665F) against platelet agglutination in vitro and in a murine model of acute ischaemic stroke.
CONCLUSION: The limited proteolytic activity of WT ADAMTS13 in in vitro models of arterial thrombosis suggests an in vivo requirement for conformational activation. The enhanced activity of the GoF ADAMTS13 variant translates to a more pronounced protective effect in experimental stroke. This article is protected by copyright. All rights reserved. PMID: 30152919 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - August 28, 2018 Category: Hematology Authors: South K, Denorme F, Salles-Crawley II, De Meyer SF, Lane DA Tags: J Thromb Haemost Source Type: research

Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke.
Conclusion: LSG ablation could reduce VAs vulnerability after acute stroke by preventing the macrophages polarization and activation induced by sympathetic hyperactivity. PMID: 33456346 [PubMed - in process]
Source: International Journal of Medical Sciences - January 20, 2021 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Increased Renal Dysfunction, Apoptosis, and Fibrogenesis Through Sympathetic Hyperactivity After Focal Cerebral Infarction
In this study, we investigated whether sympathetic hyperactivity can cause the development of renal dysfunction, apoptosis, and fibrogenesis after focal cerebral infarction. To determine the renal consequences of focal cerebral ischemia, we subjected a mice model of transient middle cerebral artery occlusion (tMCAO) and examined systolic blood pressure, heart rate, renal structure and function, serum catecholamine, and cortisol levels, and the expression of active caspase-3 bcl-2, bax, and phosphorylated p38 MAPK after 8 weeks. We also analyzed the relationship between insular cortex infarction and acute kidney injury (AKI...
Source: Translational Stroke Research - March 12, 2021 Category: Neurology Source Type: research

Adult onset methylphenidate induced dyskinesia after stroke
Methylphenidate is a stimulant medication that is commonly used to treat attention-deficit/hyperactivity disorder (ADHD). It is also used as adjuvant therapy for improving disability after stroke. Recently, Moreau et al. reported that methylphenidate improved gait hypokinesia and freezing in patients with advanced Parkinson's disease (PD) . The most common side effects of methylphenidate are; insomnia, anorexia, weight loss, abdominal pain, headache, irritability, anxiety, tachycardia, hypertension, and motor tics. Dyskinesia as a side effect of methylphenidate is rare, and only a few cases have been reported . Most of th...
Source: Parkinsonism and Related Disorders - April 14, 2014 Category: Neurology Authors: Jeong Yeon Kim, Jong Sam Baik Tags: Letters to the Editor Source Type: research

Attention and executive functioning profiles in children following perinatal arterial ischemic stroke.
This study examines the attention and executive functioning (EF) profiles of children following PAIS, as well as the impact of age and sex. In this single-center cross-sectional study, 40 children aged 3 to 16 years (median age 7.2 years; 58% male) who have suffered a PAIS underwent a comprehensive neuropsychological battery to assess attention and EF. Parents completed behavioral questionnaires regarding real-world functioning. Composite scores were calculated for seven attention and EF domains (Attention, Working Memory, Verbal Retrieval, Inhibitory Control, Flexibility/Shifting, Planning/Organization, and Processing Sp...
Source: Child Neuropsychology - September 6, 2016 Category: Child Development Authors: Bosenbark DD, Krivitzky L, Ichord R, Jastrzab L, Billinghurst L Tags: Child Neuropsychol Source Type: research

Analysis of Chinese Medical Syndrome Features of Ischemic Stroke Based on Similarity of Symptoms Subgroup
ConclusionsThere were 7 main symptom similarity-based subgroups in ischemic stroke patients, and their specific characteristics were obvious. The main syndromes were wind phlegm pattern and hyperactivity of Gan yang pattern.
Source: Chinese Journal of Integrative Medicine - June 20, 2022 Category: Internal Medicine Source Type: research