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Interpretation of myocardial injury subtypes in COVID-19 disease per fourth version of universal definition of myocardial infarction
Conclusions: Objective description of myocardial injury according to the 4th UDMI in current COVID-19 pandemic is crucial in order to discriminate patients with acute myocardial infarction and acute, chronic or incident myocardial injury.PMID:33998352 | DOI:10.1080/1354750X.2021.1921031
Source: Biomarkers - May 17, 2021 Category: Research Authors: Christian Salbach Matthias Mueller-Hennessen Moritz Biener Kiril Stoyanov Michael Preusch Lars Kihm Uta Merle Paul Schnitzler Hugo A Katus Evangelos Giannitsis Source Type: research

Viruses, Vol. 13, Pages 700: Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms
id J Alzahrani Aristóteles Góes-Neto Vasco Azevedo Preetam Ghosh Debmalya Barh The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-term care of COVID-19 survivors. It is thus imperative to study post-COVID (i.e., short-term) and long-COVID (i.e., long-term) effects, specifically as local and systemic pathophysiological outcomes of other coronavirus-related diseases (such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS)) were well-cataloged. We conducted a comprehensive review of adverse post-COVID health outcomes and potential long-COV...
Source: Viruses - April 18, 2021 Category: Virology Authors: Bruno Silva Silva Andrade S érgio Siqueira Wagner Rodrigues de Assis de Assis Soares Fernanda de Souza de Souza Rangel Naiane Oliveira Santos Andria dos Santos dos Santos Freitas Priscila Ribeiro da Ribeiro da Silveira Sandeep Tiwari Khalid J Alzahrani A Tags: Review Source Type: research

Cardiovascular and Cerebrovascular Complications With COVID-19
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 has affected the health of people across the globe. Cardiovascular diseases (CVDs) have a significant relationship with COVID-19, both as a risk factor and prognostic indicator, and as a complication of the disease itself. In addition to predisposing to CVD complications, the ongoing pandemic has severely affected the delivery of timely and appropriate care for cardiovascular conditions resulting in increased mortality. The etiology behind the cardiac injury associated with severe acute respiratory syndrome coronavirus-2 i...
Source: Cardiology in Review - April 17, 2021 Category: Cardiology Tags: Review Articles Source Type: research

How Does SARS-CoV-2 Infection Affect Survival of Emergency Cardiovascular Patients? A Cohort Study From a German Insurance Claims Database
CONCLUSION: This retrospective analysis of claims data has provided hints of an association between the COVID-19 pandemic and increased in hospital mortality in patients with acute stroke. Furthermore, confirmed SARS-CoV-2 infection was associated with increased mortality in patients with stroke, TIA, and ALI. Future studies are urgently needed to better understand the underlying mechanism and relationship between the new coronavirus and acute stroke.PMID:33824066 | DOI:10.1016/j.ejvs.2021.03.006
Source: PubMed: Eur J Vasc Endovasc ... - April 7, 2021 Category: Surgery Authors: Christian-Alexander Behrendt Moritz Seiffert Christian Gerloff Helmut L'Hoest Laura Acar G ötz Thomalla Source Type: research

Atrial appendage angiotensin-converting enzyme-2, aging and cardiac surgical patients: a platform for understanding aging-related coronavirus disease-2019 vulnerabilities
Purpose of review Hospitalizations for COVID-19 dramatically increase with age. This is likely because of increases in fragility across biological repair systems and a weakened immune system, including loss of the cardiorenal protective arm of the renin--angiotensin system (RAS), composed of angiotensin-converting enzyme-2 (ACE2)/angiotensin-(1--7) [Ang-(1--7)] and its actions through the Mas receptor. The purpose of this review is to explore how cardiac ACE2 changes with age, cardiac diseases, comorbid conditions and pharmaceutical regimens in order to shed light on a potential hormonal unbalance facilitating SARs-CoV...
Source: Current Opinion in Anaesthesiology - March 12, 2021 Category: Anesthesiology Tags: SPECIAL COMMENTARIES Source Type: research

Pneumonia in older adults
Purpose of review The purpose of this review is to address the relevant issues surrounding older adults with community-acquired pneumonia (CAP) today. Recent findings Approximately 1 million people>65 years have CAP in the US per year, which is more than previously reported (or realized). Older adults are vulnerable to the increasing prevalence of viral CAP, as the SARS-CoV-2 pandemic emphasizes, but pneumococcus is still the most common pathogen to cause CAP. Racial disparities continue to need to be addressed in order to improve early and late outcomes of older adults with CAP. Summary The epidemiolog...
Source: Current Opinion in Infectious Diseases - March 11, 2021 Category: Infectious Diseases Tags: RESPIRATORY INFECTIONS: Edited by Michael S. Niederman Source Type: research

Does a history of cardiovascular disease or cancer affect mortality after SARS-CoV-2 infection?
Tidsskr Nor Laegeforen. 2020 Dec 29;140(2). doi: 10.4045/tidsskr.20.0956. Print 2021 Feb 2.ABSTRACTBACKGROUND: Cardiovascular disease and cancer have been described as possible risk factors for COVID-19 mortality. The purpose of this study was to investigate whether a history of cardiovascular disease or cancer affects the risk of dying after a COVID-19 diagnosis in Norway.MATERIAL AND METHOD: Data were compiled from the Norwegian Surveillance System for Communicable Diseases, the Norwegian Cardiovascular Disease Registry and the Cancer Registry of Norway. Univariable and multivariable regression models were used to calcul...
Source: Tidsskrift for den Norske Laegeforening - February 2, 2021 Category: General Medicine Authors: Rune Kv åle Kaare Harald B ønaa Rachel Forster Kirsten Gravningen P étur Benedikt Júlíusson Tor Åge Myklebust Source Type: research

Late-onset myocardial infarction and autoimmune haemolytic anaemia in a COVID-19 patient without respiratory symptoms, concomitant with a paradoxical increase in inflammatory markers: a case report
ConclusionsBoth complications occurred quite late after COVID-19 diagnosis and were probably precipitated by systemic inflammation, as indicated by a significant delayed increase in inflammatory markers, including interleukin-6 (IL-6).
Source: Journal of Medical Case Reports - December 18, 2020 Category: General Medicine Source Type: research

Thrombotic Complications of COVID-19 Infection: A Review
The novel coronavirus (severe acute respiratory syndrome CoV-2 [SARS-CoV-2]), also known as COVID-19, is a single-stranded enveloped RNA virus that created a Public Health Emergency of International Concern in January 2020, with a global case burden of over 15 million in just 7 months. Infected patients develop a wide range of clinical manifestations—typically presenting with fever, cough, myalgia, and fatigue. Severely ill patients may fall victim to acute respiratory distress syndrome, acute heart injuries, neurological manifestations, or complications due to secondary infections. These critically ill patients are also...
Source: Cardiology in Review - December 13, 2020 Category: Cardiology Tags: Review Articles Source Type: research

Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19
This JAMA Insights review summarizes the pathophysiology underlying the thrombotic diathesis characteristic of acute SARS-CoV-2 infection and current recommendations for the prevention, diagnosis, and management of the most common thrombotic complications in COVID-19, including acute myocardial infarction (AMI), ischemic stroke, and venous thromboembolism (VTE).
Source: JAMA - Journal of the American Medical Association - November 23, 2020 Category: General Medicine Source Type: research

Pulmonary Endothelial Dysfunction and Thrombotic Complications in COVID-19 Patients.
This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/). PMID: 33180562 [PubMed - as supplied by publisher]
Source: Am J Respir Cell Mol... - November 12, 2020 Category: Respiratory Medicine Authors: Rodríguez C, Luque N, Blanco I, Sebastian L, Barberà JA, Peinado VI, Tura-Ceide O Tags: Am J Respir Cell Mol Biol Source Type: research

Elevated Blood Clotting Factor Linked to Worse COVID-19 Outcomes
WEDNESDAY, Sept. 16, 2020 -- Most people now know that COVID-19 can cause blood clots, potentially leading to paralysis, stroke, heart attack and death. While it ' s not clear precisely how SARS-CoV-2 causes clots, a new study suggests that the...
Source: Drugs.com - Daily MedNews - September 16, 2020 Category: General Medicine Source Type: news

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