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Total 541 results found since Jan 2013.

Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study
We examined the associations between DSR and subsequent total and cause-specific mortality among 451,390 adults enrolled in the European Prospective Investigation into Cancer and Nutrition (EPIC) study (1992 to 2014, median follow-up: 17 years), free of cancer, diabetes, heart attack, or stroke at baseline. Usual dietary intakes were assessed at recruitment with country-specific dietary questionnaires (DQs). DSR of an individual ’s yearly diet was calculated based on the absolute number of unique biological species in each (composite) food and drink. Associations were assessed by fitting multivariable-adjusted Cox propor...
Source: PLoS Medicine - October 18, 2021 Category: Internal Medicine Authors: Giles T. Hanley-Cook Source Type: research

U.S. Task Force Reconsiders Daily Low-Dose Aspirin Use for Preventing Heart Attacks in Adults Over 60
Older adults without heart disease shouldn’t take daily low-dose aspirin to prevent a first heart attack or stroke, an influential health guidelines group said in preliminary updated advice released Tuesday. Bleeding risks for adults in their 60s and up who haven’t had a heart attack or stroke outweigh any potential benefits from aspirin, the U.S. Preventive Services Task Force said in its draft guidance. For the first time, the panel said there may be a small benefit for adults in their 40s who have no bleeding risks. For those in their 50s, the panel softened advice and said evidence of benefit is less clear....
Source: TIME: Health - October 12, 2021 Category: Consumer Health News Authors: Lindsey Taylor/AP Tags: Uncategorized healthscienceclimate Research wire Source Type: news

Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study
AbstractThe association between bone mineral density (BMD) and cardiovascular disease (CVD) is not fully understood. We evaluated BMD as a risk factor for cardiovascular disease and specifically atrial fibrillation (AF), acute myocardial infarction (AMI), ischemic (IS) and hemorrhagic stroke (HS) and heart failure (HF) in men and women. This prospective population cohort utilized data on 22 857 adults from the second and third surveys of the HUNT Study in Norway free from CVD at baseline. BMD was measured using single and dual-energy X-ray absorptiometry in the non-dominant distal forearm and T-score was calculated. Hazard...
Source: European Journal of Epidemiology - September 13, 2021 Category: Epidemiology Source Type: research

Importance of attributes and willingness to pay for oral anticoagulant therapy in patients with atrial fibrillation in China: A discrete choice experiment
by Jiaxi Zhao, Hao Wang, Xue Li, Yang Hu, Vincent K. C. Yan, Carlos K. H. Wong, Yutao Guo, Marco K. H. Cheung, Gregory Y. H. Lip, Chung-Wah Siu, Hung-Fat Tse, Esther W. Chan BackgroundAdherence to oral anticoagulant therapy in patients with atrial fibrillation (AF) in China is low. Patient preference, one of the main reasons for discontinuation of oral anticoagulant therapy, is an unfamiliar concept in China. Methods and findingsA discrete choice experiment (DCE) was conducted to quantify patient preference on 7 attributes of oral anticoagulant therapy: antidote (yes/no), food –drug interaction (yes/no), frequency of blo...
Source: PLoS Medicine - August 26, 2021 Category: Internal Medicine Authors: Jiaxi Zhao Source Type: research

FDA Approves Expanded Peripheral Artery Disease (PAD) Indication for XARELTO ® (rivaroxaban) Plus Aspirin to Include Patients After Lower-Extremity Revascularization (LER) Due to Symptomatic PAD
RARITAN, N.J., August 24, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved an expanded peripheral artery disease (PAD) indication for the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) to include patients following recent lower-extremity revascularization (LER) due to symptomatic PAD. The approval is based on data from the Phase 3 VOYAGER PAD study. With this approval, XARELTO® is the first and only therapy indicated to help reduce the risks of major cardiovascular (CV) events in p...
Source: Johnson and Johnson - August 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Educational Program Improved Senior Preparedness to Call 911 as a Response to Stroke
Cardiovascular and cerebrovascular diseases are the leading causes of death in most parts of the world.1 Even though treatment is available, its benefit is highly time-dependent.2,3 Frequently, a minority of patients receive appropriate therapy4 due to low public stroke and heart attack awareness, which leads to delays in medical emergency activation.5 –7
Source: Journal of Stroke and Cerebrovascular Diseases - August 24, 2021 Category: Neurology Authors: Ekaterina Volevach, Hana Mar šálková, Jan Bobek, Veronika Svobodová, Robert Mikulik Source Type: research

Patient Preferences of Low-Dose Aspirin for Cardiovascular Disease and Colorectal Cancer Prevention in Italy: A Latent Class Analysis
ConclusionPatient preferences for the benefits and risks of low-dose aspirin differ significantly among people eligible for treatment as primary or secondary CVD prevention.
Source: The Patient - Patient-Centered Outcomes Research - August 19, 2021 Category: International Medicine & Public Health Source Type: research

Social Determinants of Health and Cardiovascular Disease: Current State and Future Directions Towards Healthcare Equity
We examined existing evidence of the association between SDOH —organized into 6 domains, including economic stability, education, food, neighborhood and physical environment, healthcare system, and community and social context—and CVD. Greater social adversity, defined by adverse SDOH, was linked to higher burden of CVD risk factors and poor outcomes, such as stroke, myocardial infarction (MI), coronary heart disease, heart failure, and mortality. Conversely, favorable social conditions had protective effects on CVD.Upstream SDOH interact across domains to produce cumulativedownstream effects on CV health, via multiple...
Source: Current Atherosclerosis Reports - July 26, 2021 Category: Cardiology Source Type: research

The association between cardiovascular risk factors and major cardiovascular diseases decreases with increasing frailty levels in geriatric outpatients
CONCLUSION: Frailty and CVRF are both associated with CVD, but the impact of CVRF decreases in the presence of frailty. When confirmed in longitudinal studies, randomized controlled trials or causal inference methods like Mendelian randomization should be applied to assess whether a shift from traditional CVRF to frailty would improve cardiovascular outcome in the oldest old.PMID:34265412 | DOI:10.1016/j.exger.2021.111475
Source: Experimental Gerontology - July 15, 2021 Category: Geriatrics Authors: Ivan Aprahamian Marina Petrella Everson C Robello H élder Jorge Andrade Gomes Nat ália A Lima Isabela C Fernandes Fernanda Rezende Dias da Silva Daniele Lima da Costa Andr éia Pain Mateus de Oliveira Reis Claudia K Suemoto Richard C Oude Voshaar Source Type: research

Age and Life-Sustaining Treatment Preferences in Parkinson Disease
Conclusions Advancing age in PD may correlate with paradoxically more aggressive goals as it relates to life-sustaining treatment preferences including cardiopulmonary resuscitation. This may reflect a response to heightened concern among older adults with PD about the potential for compromised autonomy in the setting of aging.
Source: Neurology Clinical Practice - June 7, 2021 Category: Neurology Authors: Jackowiak, E., Szpara, A., Kotagal, V. Tags: Parkinson's disease/Parkinsonism, Palliative care Research Source Type: research

Clinical and Biochemical Signs of Polycystic Ovary Syndrome in Young Women Born Preterm
CONCLUSIONS: Women born preterm have a more hyperandrogenic hormonal profile, and those born LPT are approximately three times more likely at risk to have PCOS compared to women born at term.PMID:34081616 | DOI:10.1530/EJE-20-1462
Source: European Journal of Endocrinology - June 3, 2021 Category: Endocrinology Authors: Marika Paalanne Marja V ääräsmäki Sanna Mustaniemi Marjaana Tikanm äki Karoliina Wehkalampi Hanna-Maria Matinolli Johan Eriksson Marjo-Riitta Jarvelin Laure Morin-Papunen Eero Kajantie Source Type: research