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Total 6645 results found since Jan 2013.

Nettle Allergy: a Review and Clinical Perspective
The objectives of this article are to review the available literature regarding the geographic distribution of nettle, allergen(s) involved, cross-reactivity, role in allergic rhinitis, immunotherapy efficacy, and provide a clinical perspective on the evaluation and treatment of nettle sensitized patients.Recent findingsStinging nettle (Urtica dioica) is a bi-annual pollinator with worldwide distribution and wide use in homeopathy. Limited data suggest that nettle pollen allergens may be considered clinically relevant and that nettle pollen allergy may be underestimated. More recent allergomic analysis of nettle pollen has...
Source: Current Treatment Options in Allergy - September 1, 2018 Category: Allergy & Immunology Source Type: research

Uncontrolled allergy is associated with significant productivity loss among working americans
Uncontrolled allergic rhinitis negatively impacts workplace productivity. House dust mite (HDM) is the most prevalent perennial allergy, but it can be effectively treated with allergy immunotherapy (AIT). Subcutaneous injection (SCIT) is the most common route of HDM AIT, however SCIT itself can adversely affect workplace productivity when the travel time required to receive the injections overlaps the workday.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2018 Category: Allergy & Immunology Authors: M. Aagren, E. Hammerby Tags: P111 Source Type: research

Clinical peculiarities of seasonal respiratory allergy in children
Conclusion: Presence of mold hypersensitivity in children determines more severe nasal and bronchial symptoms, lower asthma control and prolonged exacerbation (p<0,05).
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Kuznietsova, O., Nedelska, S. Tags: Allergy and immunology Source Type: research

Characteristics of Adult Severe Refractory Asthma in Korea Analyzed From the Severe Asthma Registry.
CONCLUSIONS: The baseline characteristics of severe asthma patients in the Korea Severe Asthma Registry were analyzed and reported for the first time. With this cohort, further prospective studies should be performed to search for ways to improve management of severe refractory asthma. PMID: 30479076 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 29, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

3-Methyl-4-nitrophenol triggers nasal allergy by modulating dendritic cell properties
This study aims to elucidate the role of MNP in regulation of dendritic cell (DC) properties and facilitation of allergic rhinitis.
Source: Journal of Allergy and Clinical Immunology - November 22, 2018 Category: Allergy & Immunology Authors: Xiao-Yu Liu, Yong-Jin Wu, Li-Juan Song, Xian-Hai Zeng, Shuai Wang, Jiang-Qi Liu, Li-Hua Mo, Xiao-Rui Geng, Li-Teng Yang, Rui-Di Xie, Xiao-Wen Zhang, Zhi-Gang Liu, Ping-Chang Yang Tags: Letter to the Editor Source Type: research

Report from the National Institute of Allergy and Infectious Diseases Workshop on “Atopic Dermatitis and the Atopic March: Mechanisms and Interventions”
Atopic dermatitis (AD) affects up to 20% of children world-wide and is an increasing public health problem particularly in developed countries. Although AD in infants and young children can resolve, there is a well-recognized, increased risk of sequential progression from AD to other atopic diseases including food allergy, allergic rhinitis, allergic asthma and allergic rhinoconjunctivitis; a process referred to as the “atopic march”. The mechanisms underlying the development of AD and subsequent progression to other atopic comorbidities, particularly food allergy, are incompletely understood and the subject of intense investigation.
Source: Journal of Allergy and Clinical Immunology - January 9, 2019 Category: Allergy & Immunology Authors: Wendy F. Davidson, Donald Y.M. Leung, Lisa A. Beck, Cecilia M. Berin, Mark Boguniewicz, William W. Busse, Talal A. Chatila, Raif S. Geha, James E. Gern, Emma Guttman-Yassky, Alan D. Irvine, Brian S. Kim, Heidi H. Kong, Gideon Lack, Kari C. Nadeau, Julie S Source Type: research

Demographic, Clinical, and Allergic Characteristics of Children with Eosinophilic Esophagitis in Isfahan, Iran.
Abstract Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease isolated to the esophagus Food allergy is thought to play an important role in the pathophysiology of EOE. The aim of this study is to evaluate demographic features and sensitivity of patients with reference to common food allergens. Children with documented EoE were enlisted for this study. Skin prick test and patch test were done for all participants. Each test contained common food allergens. Other tests, such as evaluation of total IgE and eosinophil count, were also done. A total of 30 patients (the mean age of participants was 3±6 ...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 3, 2018 Category: Allergy & Immunology Authors: Momen T, Saneian H, Amini N Tags: Iran J Allergy Asthma Immunol Source Type: research

The Comparation of Intraperitoneal Injection and Nasal-only Delivery Allergic Rhinitis Model Challenged With Different Allergen Concentration.
CONCLUSION: The IP injection model and the nasal-only delivery model are 2 typical models for AR that causes a different immune response. A positive dose-response relationship in the nasal-only delivery model is observed from 25 mg/mL to 0.025 mg/mL. PMID: 30871345 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - February 28, 2019 Category: ENT & OMF Authors: Wang Y, Zhou Y, Zhu Y, Yu W, Wang J, Fu J, Yuan Y, Yu Z, Chen S, Wang Y, Chen J, Kong W Tags: Am J Rhinol Allergy Source Type: research

Altered Sphingolipid Metabolism Is Associated With Asthma Phenotype in House Dust Mite-Allergic Patients.
CONCLUSIONS: Altered sphingolipid metabolism, with augmented synthesis of S1P and impaired de novo sphingolipid synthesis in response to allergen challenge, may participate in the development of asthma phenotype in HDM-APs. PMID: 30912323 [PubMed]
Source: Allergy, Asthma and Immunology Research - March 27, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
CONCLUSIONS: AM could reduce the secretion of inflammatory cytokines by increasing the level of CD4+ CD25+ Foxp3+ T cells and inhibiting the activation of the NF-κB. PMID: 30945558 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - April 3, 2019 Category: ENT & OMF Authors: Bing Z, Jin-Tao D, Feng L, Ba L, Ya-Feng L, Shi-Xi L Tags: Am J Rhinol Allergy Source Type: research

Atopy and Quality of Life in Pediatric Chronic Rhinosinusitis.
CONCLUSION: In conclusion, we recommend that testing for aeroallergen sensitivity and assessment of quality of life should be included in the protocol for diagnosis and management of pediatric patients with CRS. Early diagnosis and treatment of allergy may halt the progression of CRS and also the development of asthma and other allergic multimorbid disorders. PMID: 31161768 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - June 3, 2019 Category: ENT & OMF Authors: Anamika A, Chakravarti A, Kumar R Tags: Am J Rhinol Allergy Source Type: research

Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis.
CONCLUSIONS: UR-SCIT with tyrosine-adsorbed HDM extract conducted in an outpatient clinic was tolerable in patients with AD and AR. UR-SCIT can be a useful method to start a SCIT in patients with AD and AR. PMID: 31552719 [PubMed]
Source: Allergy, Asthma and Immunology Research - September 27, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Study on the effect of phototherapy for inhibition of symptoms associated with allergic rhinitis.
The objective of the study was to compare the efficacy of the phototherapy device on the relief of a range of symptoms provoked by indoor and outdoor allergens. A phototherapy emits visible light (mUV/VIS) and infrared light, and was compared to a placebo device which did not emit light on two groups of allergic rhinitis sufferers. Rhinophototherapy improved nasal symptoms of allergic rhinitis arising from exposure to indoor and outdoor allergens. The difference in the intensity of symptoms scored at the baseline, and at the final visit for the group using the photoperiod device was significantly lower. The device could po...
Source: European Annals of Allergy and Clinical Immunology - October 10, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Prevalence of allergic rhinitis in children with otitis media with effusion.
Conclusion. Allergic rhinitis and larger family household appeared to be common risk factors in children with persistent otitis media with effusion. There is significant hearing loss noted in children suffering from otitis media with effusion and allergic rhinitis. The hearing threshold improved remarkably with medical therapy. This study hence clarifies the controversy on the association between allergic rhinitis and otitis media with effusion. PMID: 31668057 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - November 2, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

A300 elevated allergic comorbidity in patients with food protein-induced enterocolitis
Despite being classified as an allergy, the epidemiologic relationships between food protein-induced enterocolitis syndrome (FPIES) and other allergic manifestations (atopic dermatitis, AD; IgE-mediated food allergy, IgE-FA; asthma; allergic rhinitis, AR) are not well understood.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: M. Ruffner, K. Wang, J. Dudley, A. Cianferoni, R. Grundmeier, J. Spergel, T. Brown-Whitehorn, D. Hill Tags: Food Allergy Source Type: research