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Condition: Aortic Aneurysm

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Total 540 results found since Jan 2013.

Femoral Neuropathy Following Spontaneous Retroperitoneal Hemorrhage After Cardiac Surgery: A Case Report
A woman underwent ascending aortic aneurysm repair, aortic root and valve replacement, and coronary artery bypass grafting. Her postoperative course was complicated by stroke and status epilepticus. With supportive care and antiepileptics, her neurologic status improved. Intravenous heparin and aspirin were initiated. On postoperative day 13, she developed a large retroperitoneal hematoma with femoral neuropathy. Because her hematoma was not amenable to percutaneous drainage or surgical evacuation, and considering her comorbidities, a conservative approach was elected. Anticoagulation was held but not reversed, and she was...
Source: A&A Case Reports - April 14, 2017 Category: Anesthesiology Tags: Case Reports: Case Report Source Type: research

Retrospective analysis of Spinal Cord Infarction after Aortic Repair (P6.300)
Conclusions:The rate of spinal cord infarction after aortic repair is low overall, but is higher after repair of a ruptured aortic aneurysm or dissection.Study Supported by:Dr. Gialdini is supported by the Feil Family Foundation.Dr. Kamel is supported by NIH grants K23NS082367 and R01NS097443 as well as the Michael Goldberg Research Fund.Disclosure: Dr. Gialdini has nothing to disclose. Dr. Merkler has nothing to disclose. Dr. Parikh has nothing to disclose. Dr. Lerario has nothing to disclose. Dr. Chatterjee has nothing to disclose. Dr. Kamel has received personal compensation for activities with Genentech as a speaker. D...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gialdini, G., Merkler, A., Parikh, N., Lerario, M., Chatterjee, A., Kamel, H. Tags: Cardiovascular Issues in Ischemic Stroke Source Type: research

Deriving literature-based benchmarks for surgical complications in high-income countries: a protocol for a systematic review and meta-analysis
This study of secondary data does not require ethics approval. It will be presented internationally and published in the peer-reviewed literature. Results will inform a future quality improvement tool and provide benchmarks of surgical complication rates within HICs. Trial registration International Prospective Register of Systematic Reviews (PROSPERO). Registration number CRD42016037519.
Source: BMJ Open - May 9, 2017 Category: General Medicine Authors: Brindle, M. E., Roberts, D. J., Daodu, O., Haynes, A. B., Cauley, C., Dixon, E., La Flamme, C., Bain, P., Berry, W. Tags: Open access, Health policy Protocol Source Type: research

Optimal vs Feasible Volume Thresholds in Vascular Surgery
The volume-outcome relationship in vascular surgery has been an especially controversial topic recently, given the declining trainee exposure to complex open vascular cases, additional series reporting improved outcomes with higher volume, and medical organizations, such as Leapfrog, recommending volume thresholds for certain procedures. However, the definition of volume and the delineation of a specific threshold number of cases below which surgeons should not be credentialed remain unclear. In this issue ofJAMA Surgery, Mao et al took a unique approach to looking at outcomes among the very lowest-volume surgeons —those...
Source: JAMA Surgery - May 17, 2017 Category: Sports Medicine Source Type: research

Endovascular treatment for ruptured abdominal aortic aneurysm.
CONCLUSIONS: The conclusions of this review are currently limited by the paucity of data. We found from the data available moderate-quality evidence suggesting there is no difference in 30-day mortality between eEVAR and open repair. Not enough information was provided for complications for us to make a well-informed conclusion, although it is possible that eEVAR is associated with a reduction in bowel ischaemia. Long-term data were lacking for both survival and late complications. More high-quality randomised controlled trials comparing eEVAR and open repair for the treatment of RAAA are needed to better understand if one...
Source: Cochrane Database of Systematic Reviews - May 26, 2017 Category: General Medicine Authors: Badger S, Forster R, Blair PH, Ellis P, Kee F, Harkin DW Tags: Cochrane Database Syst Rev Source Type: research

Sex Differences in Vascular Physiology and Pathophysiology: Estrogen and Androgen Signaling in Health and Disease.
Abstract Sex differences between women and men are often overlooked and underappreciated when studying the cardiovascular system. It has been long assumed that men and women are physiologically similar, and this notion has resulted in females being clinically evaluated and treated for cardiovascular pathophysiological complications as males. Currently, there is increased recognition of fundamental sex differences in cardiovascular function, anatomy, cell signaling, and pathophysiology. NIH has enacted guidelines expressly to gain knowledge about ways the sexes differ in both normal function and diseases at the var...
Source: American Journal of Physiology. Heart and Circulatory Physiology - June 16, 2017 Category: Physiology Authors: Boese AC, Kim SC, Yin KJ, Lee JP, Hamblin MH Tags: Am J Physiol Heart Circ Physiol Source Type: research

Sex and Circadian Periodicity of Cardiovascular Diseases
Women are often excluded/underrepresented in clinical trials; sometimes, the number of men/women participants or separate analysis by sex are not reported. A robust body of evidence demonstrated that several life-threatening acute cardiovascular diseases, for example, acute myocardial infarction, sudden cardiac death, cardiac arrest, rupture or dissection of aortic aneurysms, and stroke, exhibit a circadian periodicity with a morning peak. An analysis of 20  years of chronobiologic studies (44% of them, accounting for 85% of total cases, with separate analysis by sex) confirmed that morning hours are a critical time of on...
Source: Heart Failure Clinics - June 29, 2017 Category: Cardiology Authors: Roberto Manfredini, Raffaella Salmi, Rosaria Cappadona, Fulvia Signani, Stefania Basili, Niki Katsiki Source Type: research

Rethinking the Paradigm: Modern Approach to Proximal Aortic Reconstruction Demonstrates Excellent Outcomes.
CONCLUSION: Elective surgery for aneurysm of the proximal aorta is safe, reproducible, and is associated with outcomes that are superior to those seen in an acute aortic syndrome. It may be appropriate to offer surgery to younger patients with proximal aortic aneurysms at smaller diameters, even if their aortic dimensions do not yet meet traditional guidelines for surgical intervention. PMID: 28671863 [PubMed - in process]
Source: The Heart Surgery Forum - June 20, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Hemli JM, R DeLaney ER, Dholakia KR, Perk D, Patel NC, Scheinerman SJ, Brinster DR Tags: Heart Surg Forum Source Type: research

Central cannulation strategy for extent I thoracoabdominal aneurysm repair of chronic type B aortic dissection
ConclusionsCentral true lumen cannulation through a left thoracotomy incision for repair of extent I TAAA with chronic type B dissection is an acceptable approach with equivalent early and midterm outcomes compared to more standard femoral cannulation techniques. It may provide a safe alternative cannulation site for patients with diseased femoral vessels.
Source: Journal of Cardiac Surgery - July 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Reilly D. Hobbs, Tyler J. Wallen, Caroline M. Komlo, Patrick J. Moeller, Alberto Pochettino, Joseph E. Bavaria, Prashanth Vallabhajosyula Tags: ORIGINAL ARTICLE Source Type: research

Adiponectin, lipids and atherosclerosis
Purpose of review: Adiponectin is an adipokine with anti-inflammatory, antioxidant, antiatherogenic, pro-angiogenic, vasoprotective and insulin-sensitizing properties. Several factors may influence adiponectin levels, such as genetic polymorphisms, obesity / body fat distribution, diet and exercise as well as cardiovascular risk factors such as sleep deprivation and smoking as well as medications. Adiponectin has been proposed as a potential prognostic biomarker and a therapeutic target in patients with cardiometabolic diseases. Recent findings: This narrative review discusses the associations of adiponectin with obesity-...
Source: Current Opinion in Lipidology - July 14, 2017 Category: Lipidology Tags: HYPERLIPIDAEMIA AND CARDIOVASCULAR DISEASE: Edited by Paul N. Durrington Source Type: research

Management of hemothorax after thoracic endovascular aortic repair for ruptured aneurysms.
Conclusions The morbidity and mortality of ruptured degenerative thoracic aortic aneurysms remains high despite the introduction of TEVAR. In this single-center experience, there was a trend toward decreased respiratory complications and increased survival with early chest decompression of hemothorax after TEVAR. PMID: 28699426 [PubMed - as supplied by publisher]
Source: Vascular - January 1, 2017 Category: Surgery Authors: Ju MH, Nooromid MJ, Rodriguez HE, Eskandari MK Tags: Vascular Source Type: research

Rates of Spinal Cord Infarction After Repair of Aortic Aneurysm or Dissection Clinical Sciences
Background and Purpose—The rate of spinal cord infarction (SCI) after surgical or endovascular repair of an aortic aneurysm or dissection is unclear.Methods—Using administrative claims data, we identified adult patients discharged from nonfederal acute care hospitals in California, New York, and Florida who underwent surgical or endovascular repair of an aortic aneurysm or dissection between 2005 and 2013. Patients with SCI diagnosed before the aortic repair were excluded. Our primary outcome was an SCI during the index hospitalization for aortic repair. Descriptive statistics were used to estimate crude rates of SCI. ...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Gino Gialdini, Neal S. Parikh, Abhinaba Chatterjee, Michael P. Lerario, Hooman Kamel, Darren B. Schneider, Babak B. Navi, Santosh B. Murthy, Costantino Iadecola, Alexander E. Merkler Tags: Cardiovascular Surgery, Revascularization, Aneurysm, Aortic Dissection Original Contributions Source Type: research

Smoking and blood pressure: A complex relationship.
Abstract Hypertension and tobacco smoking are two major modifiable risk factors for atheromatous disease and its cardiovascular complications. If systolic hypertension (SBP≥140mmHg and DBP<90mmHg) is the leading risk factor for stroke, smoking (nicotine) has a more powerful impact on coronary events, aortic aneurysms, and peripheral artery disease. Smoking can transiently modify the regulation of blood pressure (BP) by a swift effect on the autonomic nervous system. It also accelerates arterial aging, which plays a role in chronic hypertension. Chronic sympathetic activation induced by tobacco smoking also ha...
Source: Presse Medicale - July 28, 2017 Category: General Medicine Authors: Madika AL, Mounier-Vehier C Tags: Presse Med Source Type: research

Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease
Sex differences between women and men are often overlooked and underappreciated when studying the cardiovascular system. It has been long assumed that men and women are physiologically similar, and this notion has resulted in women being clinically evaluated and treated for cardiovascular pathophysiological complications as men. Currently, there is increased recognition of fundamental sex differences in cardiovascular function, anatomy, cell signaling, and pathophysiology. The National Institutes of Health have enacted guidelines expressly to gain knowledge about ways the sexes differ in both normal function and diseases a...
Source: AJP: Heart and Circulatory Physiology - September 5, 2017 Category: Cardiology Authors: Boese, A. C., Kim, S. C., Yin, K.-J., Lee, J.-P., Hamblin, M. H. Tags: REVIEW Source Type: research

Extended Serum Lipid Profile Predicting Long-Term Survival in Patients Treated for Abdominal Aortic Aneurysms
ConclusionsExtended serum lipid parameters complement risk prediction of patients treated for AAAs. An unfavourable lipid profile is associated with treatment of AAA earlier in life and with inferior long-term survival.
Source: World Journal of Surgery - October 12, 2017 Category: Surgery Source Type: research