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Condition: Chronic Kidney Disease
Procedure: Kidney Transplant
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Total 7411 results found since Jan 2013.
The effect of exercise on vascular health in chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Am J Physiol Renal Physiol. 2023 Sep 21. doi: 10.1152/ajprenal.00152.2023. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) are at increased risk of cardiovascular disease. This increased risk cannot be fully explained by traditional risk factors such as hypertension. Endothelial dysfunction and arterial stiffness have been suggested as factors which explain some of the increased risk, and are independently associated with important cardiovascular outcomes in CKD patients. Studies in other disease populations have shown positive effects of exercise on vascular dysfunction. The aim of this review was...
Source: Am J Physiol Renal P... - September 21, 2023 Category: Urology & Nephrology Authors: Mark D Davies Felicity Hughes Aamer Sandoo Abdulfattah Alejmi Jamie Hugo Macdonald Source Type: research
Activated carbon derived from wood biochar for Amperometric sensing of Ammonia for early screening of chronic kidney disease
In this study, we have elucidated the functionality and usefulness of a wearable microelectronic research prototype integrated with an HTC-activated carbon @RTIL-based electrochemical sensing platform for detecting ammonia levels released from the skin as a marker for chronic kidney disease screening. By enabling early detection and monitoring, these platforms can facilitate timely interventions, such as lifestyle modifications, medication adjustments, or referral to nephrology specialists. This proactive approach can potentially slow down disease progression, minimize the need for dialysis or transplantation, and ultimate...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Ivneet Banga Anirban Paul Vikram Narayanan Dhamu Annapoorna Hochihally Ramasubramanya Sriram Muthukumar Shalini Prasad Source Type: research
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism
In this study, we demonstrated the dose-dependent attenuation of RIF by Ootheca mantidis (SPX), a commonly prescribed TCM for CKD, in a mouse model of unilateral ureteral obstruction (UUO). RNA-sequencing analysis suggested that SPX treatment prominently downregulated apoptosis and inflammation-associated pathways, thereby inhibiting the fibrogenic signaling in the kidney. We further found that transplantation of fecal microbiota from SPX-treated mice conferred protection against renal injury and fibrosis through suppressing apoptosis in UUO mice, indicating that SPX ameliorated RIF via remodeling the gut microbiota and re...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 7, 2023 Category: Drugs & Pharmacology Authors: Jue Wang Xiaozhen Guo Ziyuan Zou Minjun Yu Xueling Li Hualing Xu Yiping Chen Tingying Jiao Kanglong Wang Yuandi Ma Jie Jiang Xinyu Liang Jiawen Wang Cen Xie Yifei Zhong Source Type: research
Sodium First Approach, to Reset Our Mind for Improving Management of Sodium, Water, Volume and Pressure in Hemodialysis Patients, and to Reduce Cardiovascular Burden and Improve Outcomes
Front Nephrol. 2022 Jul 7;2:935388. doi: 10.3389/fneph.2022.935388. eCollection 2022.ABSTRACTNew physiologic findings related to sodium homeostasis and pathophysiologic associations require a new vision for sodium, fluid and blood pressure management in dialysis-dependent chronic kidney disease patients. The traditional dry weight probing approach that has prevailed for many years must be reviewed in light of these findings and enriched by availability of new tools for monitoring and handling sodium and water imbalances. A comprehensive and integrated approach is needed to improve further cardiac health in hemodialysis (HD...
Source: Atherosclerosis - September 7, 2023 Category: Cardiology Authors: Bernard Canaud Jeroen Kooman Andreas Maierhofer Jochen Raimann Jens Titze Peter Kotanko Source Type: research
Early prediction of growth patterns after pediatric kidney transplantation based on height-related single-nucleotide polymorphisms
CONCLUSIONS: A model with good performance for predicting post-transplant growth patterns in children based on SNPs and clinical variables was constructed and validated using machine learning algorithms. The model is expected to guide clinicians in the management of children after renal transplantation, including the use of growth hormone, glucocorticoid withdrawal, and nutritional supplementation, to alleviate growth retardation in children with ESRD.PMID:37672508 | DOI:10.1097/CM9.0000000000002828
Source: Chinese Medical Journal - September 6, 2023 Category: General Medicine Authors: Yi Feng Yonghua Feng Mingyao Hu Hongen Xu Zhigang Wang Shicheng Xu Yongchuang Yan Chenghao Feng Zhou Li Guiwen Feng Wenjun Shang Source Type: research
Identifying the barriers to kidney transplantation for patients in rural and remote areas: a scoping review
CONCLUSIONS: Patients in regional, rural, and remote areas face many additional barriers to kidney transplantation, which are predominantly associated with the need to travel or relocate to access required medical testing and transplantation facilities.PMID:37656389 | DOI:10.1007/s40620-023-01755-0
Source: Journal of Nephrology - September 1, 2023 Category: Urology & Nephrology Authors: Tara K Watters Beverley D Glass Andrew J Mallett Source Type: research
REIN: a tool at the service of the paediatric patients
Nephrol Ther. 2023 Aug 28;18(S2):59-64. doi: 10.1016/S1769-7255(22)00570-3.ABSTRACTOn the occasion of the 20th anniversary of the REIN (French Renal Epidemiology and Information Network), a summary work on the contributions of the national French ESKD register was carried out. On the issue of paediatric CKD patients, the following key messages were retained. Paediatric stage 5 chronic kidney disease (CKD) has particularities that require to be analysed and taken into account because the mortality of these patients remains 30 times higher than that of children of the same age. The REIN registry enables illustrating the spec...
Source: Nephrologie and Therapeutique - August 28, 2023 Category: Urology & Nephrology Authors: Étienne Bérard J érôme Harambat Julien Hogan Cyrielle Parmentier Cl émence Béchade Mathilde Lassalle Source Type: research
REIN: a tool to highlight inequalities in health
Nephrol Ther. 2023 Aug 28;18(S2):50-53. doi: 10.1016/S1769-7255(22)00568-5.ABSTRACTOn the occasion of the 20th anniversary of the REIN (French Renal Epidemiology and Information Network), a summary work on the contributions of the national French ESKD register was carried out. On the issue of Social Inequalities in Health, the following key messages were retained. Social inequalities in health exist throughout the journey of a patient with chronic kidney disease and manifest as territorial inequalities in access to home-based or independent dialysis treatment and to transplant, whether preemptive or otherwise. SIH are obse...
Source: Nephrologie and Therapeutique - August 28, 2023 Category: Urology & Nephrology Authors: Val érie Chatelet Sahar Bayat B énédicte Driollet V éronique Merle Olivier Moranne Mathilde Lassalle Source Type: research
