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297 * early and late outcomes of complex aortic root surgery in patients with aortic root abscesses
Conclusion: The surgical treatment of aortic root abscess is a challenging operation and is associated with a high early morbidity and mortality. However, the long-term survival is satisfactory.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Davierwala, P. M., Leontyev, S., Gunter, K., Bakhtiary, F., Borger, M., Misfeld, M., Mohr, F., Davierwala, P. Tags: Infective endocarditis and outcomes Source Type: research

302 * full sternotomy versus right anterior mini-thoracotomy for isolated aortic valve replacement in octogenarians: a propensity matched study
Conclusion: Minimally invasive AVR through RAMT can be safely performed in patients aged ≥80 years with acceptable morbidity and mortality rates. It is an expeditious and effective alternative to full sternotomy AVR and might be associated with lower stroke incidence.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Gilmanov, D. S., Farneti, P. A., Ferrarini, M., Santarelli, F., Murzi, M., Miceli, A., Solinas, M., Glauber, M. Tags: Infective endocarditis and outcomes Source Type: research

Have antibiotic changes upped heart infections?
Conclusion This is valuable and timely research, which has looked at trends before and after NICE's 2008 guidance on the prevention of infective endocarditis in people undergoing invasive procedures. This examined: changes in the prescription of antibiotics for the prevention of infective endocarditis changes in the number of cases of infective endocarditis diagnosed NICE's recommendation was based on an examination of the evidence of the effectiveness of antibiotics in preventing infective endocarditis, weighing the benefits and health outcomes (such as reduction in illness and deaths), risks and costs.   The ...
Source: NHS News Feed - November 19, 2014 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study)
Conclusion Rheumatic heart disease patients were young, predominantly female, and had high prevalence of major cardiovascular complications. There is suboptimal utilization of secondary antibiotic prophylaxis, oral anti-coagulation, and contraception, and variations in the use of percutaneous and surgical interventions by country income level.
Source: European Heart Journal - May 7, 2015 Category: Cardiology Authors: Zuhlke, L., Engel, M. E., Karthikeyan, G., Rangarajan, S., Mackie, P., Cupido, B., Mauff, K., Islam, S., Joachim, A., Daniels, R., Francis, V., Ogendo, S., Gitura, B., Mondo, C., Okello, E., Lwabi, P., Al-Kebsi, M. M., Hugo-Hamman, C., Sheta, S. S., Haile Tags: Valvular heart disease Source Type: research

Embolic Strokes and Relapsing Infective Endocarditis Due to Neisseria Subflava (P1.316)
CONCLUSIONS: N.subflava can be a causative agent for relapsing infective endocarditis complicated with embolic strokes. The management of stroke in the setting of IE is different and it is important to be aware of it to avoid complications.Disclosure: Dr. Rodriguez Alvarez has nothing to disclose. Dr. Pillai has nothing to disclose. Dr. Khanna has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rodriguez Alvarez, M., Pillai, A., Khanna, R. Tags: Other Bacterial Infections Source Type: research

Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis Valvular Heart Disease
Conclusions Six-month mortality after IE is 25% and is predicted by host factors, IE characteristics, and IE complications. Surgery during the index hospitalization is associated with lower mortality but is performed less frequently in the highest risk patients. A simplified risk model may be used to identify specific risk subgroups in IE.
Source: JAHA:Journal of the American Heart Association - April 17, 2016 Category: Cardiology Authors: Park, L. P., Chu, V. H., Peterson, G., Skoutelis, A., Lejko-Zupa, T., Bouza, E., Tattevin, P., Habib, G., Tan, R., Gonzalez, J., Altclas, J., Edathodu, J., Fortes, C. Q., Siciliano, R. F., Pachirat, O., Kanj, S., Wang, A., for the International Collaborat Tags: Clinical Studies, Infectious Endocarditis, Valvular Heart Disease, Mortality/Survival Source Type: research

An approach to a patient with infective endocarditis.
Authors: Hitzeroth J, Beckett N, Ntuli P Abstract Although infective endocarditis (IE) is relatively uncommon, it remains an important clinical entity with a high in-hospital and 1-year mortality. It is most commonly caused by viridans streptococci. Staphylococcus aureus is responsible for a malignant course of IE and often requires early surgery to eradicate. Other rarer causes are various bacilli, including the HACEK (Haemophilus, Actinobacillus,Cardiobacterium, Eikenella and Kingella spp.) group of organisms and fungi. The clinical presentation varies. Patients may present with a nonspecific illness, valve dysfu...
Source: South African Medical Journal - June 17, 2016 Category: African Health Tags: S Afr Med J Source Type: research

Transcatheter valve-in-valve implantation versus redo surgical aortic valve replacement in patients with failed aortic bioprostheses
CONCLUSIONS Despite a higher risk profile in the ViV group, early mortality rates were not different compared with those of surgery. Although ViV resulted in elevated transvalvular gradients and therefore a lower rate of device success, mortality rates were similar to those with redo-SAVR. At present, both techniques serve as complementary approaches, and allow individualized patient care with excellent outcomes.
Source: Interactive CardioVascular and Thoracic Surgery - January 3, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Silaschi, M., Wendler, O., Seiffert, M., Castro, L., Lubos, E., Schirmer, J., Blankenberg, S., Reichenspurner, H., Schäfer, U., Treede, H., MacCarthy, P., Conradi, L. Tags: History, Basic research vascular ADULT CARDIAC Source Type: research

Fatal Neisseria macacae infective endocarditis: first report
We present here the first case ofN. macacae infective endocarditis in a 65-year-old man with a native aortic valve infection complicated by a peri-aortic abscess. N. macacae was isolated from blood culture and was found on the cardiac valve using 16S rDNA detection. Despite an appropriate antibiotic therapy, and aortic homograft replacement, and mitral repair, the patient died 4  days after surgery from a massive hemorrhagic stroke.
Source: Infection - January 27, 2017 Category: Infectious Diseases Source Type: research

Homograft Versus Conventional Prosthesis for Surgical Management of Aortic Valve Infective Endocarditis: A Systematic Review and Meta-analysis
Conclusions Homografts and conventional prostheses offer similar survival and freedom from recurrent endocarditis and reoperation for aortic valve IE. Homografts may be associated with greater risk of reoperation compared with mechanical valves.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - May 1, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Workup and Management of Native and Prosthetic Valve Endocarditis
AbstractInfective endocarditis (IE) is associated with significant serious adverse outcomes including death. IE usually presents with diverse clinical picture and syndromic diagnoses including heart failure, stroke, and peripheral embolization. Given variable, vague, and syndromic presentations, the diagnosis of IE may be delayed for days to weeks. Maintaining a high index of suspicion among clinicians is the key to early recognition of the disease and prompt initiation of antimicrobial therapy to prevent IE-associated mortality and morbidity. Blood culture and echocardiography remain essential tools in the diagnosis of in...
Source: Current Treatment Options in Cardiovascular Medicine - August 7, 2018 Category: Cardiology Source Type: research

Surgical outcomes in Behcet’s disease patients with severe aortic regurgitation
ConclusionsThe findings suggest that mechanical root replacement combined with a low post-operative C-reactive protein level maintained through adjunctive immunomodulation therapy may lead to optimal surgical outcomes in Behcet’s disease associated with severe aortic regurgitation.
Source: The Annals of Thoracic Surgery - October 10, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Surgical outcomes in Behcet's disease patients with severe aortic regurgitation.
CONCLUSIONS: The findings suggest that mechanical root replacement combined with a low post-operative C-reactive protein level maintained through adjunctive immunomodulation therapy may lead to optimal surgical outcomes in Behcet's disease associated with severe aortic regurgitation. PMID: 30315793 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - October 10, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Ghang B, Kim JB, Jung SH, Chung CH, Lee JW, Song JM, Kang DH, Kim DH, Kim J, Yoo B, Choo SJ Tags: Ann Thorac Surg Source Type: research

A Blood Filter Fights Deadly Inflammatory Response
A new blood filtration technology may prove to be life-saving for patients whose normally healthy inflammatory response to injury or illness has gone into overdrive, resulting in fatally high levels of cytokines in their blood. In an interview with MD+DI, Dr. Phillip Chan, MD, PhD, CEO of CytoSorbents Corp., explained that inflammation, and the production of substances called cytokines that drive inflammation, are the body’s natural response to heal injury or infection. But sometimes, the inflammatory response is so severe in such conditions as sepsis and infection, burn injuries, trauma, pancreatitis, li...
Source: MDDI - October 9, 2019 Category: Medical Devices Authors: Susan Shepard Tags: Cardiovascular Source Type: news

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