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Specialty: Neurology
Condition: Cardiomyopathy

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Total 115 results found since Jan 2013.

Vascular Territories of Ischemic Stroke in Associated Takotsubo Cardiomyopathy (P1.221)
Conclusions: TC is a reversible cardiomyopathy that has an association with ischemic stroke. This condition can notably be both the cause and effect of stroke. Ischemic stroke of the left middle cerebral artery appears to be the most prevalent. In female patients suffering from middle cerebral artery distribution ischemic stroke and cardiac dysfunction, TC should be considered.Disclosure: Dr. Zia has nothing to disclose. Dr. Silliman has received research support from Genzyme Corporation, Biogen Idec, and Novartis.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zia, A., Silliman, S. Tags: Cardiac Mechanisms and Complications of Stroke Source Type: research

Chagas Disease and Stroke: Frequency and Clinical Correlates (P3.235)
Conclusions: Patients presenting with stroke and CD had more cardiac impairment and cardioembolic events than non-CD patients. Better healthcare of stroke patients and CD is required as these patients were readmitted more frequently than those without CDDisclosure: Dr. Meira has nothing to disclose. Dr. Teixeira has nothing to disclose. Dr. Nunes has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Meira, F., Teixeira, A., Nunes, M. d. C. Tags: Stroke in the Young Source Type: research

Stroke and Embolic Events in Hypertrophic Cardiomyopathy: Risk Stratification in Patients Without Atrial Fibrillation Clinical Sciences
Conclusions— The incidence of stroke and embolic events was about 1.0% per year in the HCM cohort. AF had not been previously documented before the event in more than half of patients with events. Older age and enlarged left atrial dimension are possible risk factors for embolic events in patients with HCM without documented AF.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Haruki, S., Minami, Y., Hagiwara, N. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Tit for Tat Brain versus Heart: A Case of Status Epilepticus, Cardiomyopathy, and Stroke.
PMID: 26654568 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - December 14, 2015 Category: Neurology Authors: Bharadwaj S, Rizek P, Teefy P, Gofton T Tags: Can J Neurol Sci Source Type: research

Rapid diagnosis and treatment of TIA results in low rates of stroke, myocardial infarction and vascular death
Conclusions In our TIA patients, early vascular study and detecting patients with silent cardiomyopathy may have contributed to the low rate of vascular disease recurrence.
Source: Neurologia - November 27, 2015 Category: Neurology Source Type: research

Frequency of MELAS main mutation in a phenotype-targeted young ischemic stroke patient population
Abstract Mitochondrial diseases, predominantly mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), may occasionally underlie or coincide with ischemic stroke (IS) in young and middle-aged individuals. We searched for undiagnosed patients with MELAS in a target subpopulation of unselected young IS patients enrolled in the Stroke in Young Fabry Patients study (sifap1). Among the 3291 IS patients aged 18–55 years recruited to the sifap1 study at 47 centers across 14 European countries, we identified potential MELAS patients with the following phenotypic features: (a) diagnosed cardi...
Source: Journal of Neurology - November 14, 2015 Category: Neurology Source Type: research

Takotsubo Cardiomyopathy Following Acute Cerebral Events
Conclusion: TCM can develop within the first few days after an acute cerebral event. It occurs predominantly in women with insular or posterior fossa lesions and is possibly induced by vegetative reactions.Eur Neurol 2015;74:163-168
Source: European Neurology - October 20, 2015 Category: Neurology Source Type: research

Homocysteine, Ischemic Stroke, and Coronary Heart Disease in Hypertensive Patients: A Population-Based, Prospective Cohort Study Clinical Sciences
Conclusions— Hyperhomocysteinemia in Chinese hypertensive patients is significantly associated with IS risk but not coronary heart disease susceptibility, and folic acid supplementation can efficiently reduce tHcy levels.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Han, L., Wu, Q., Wang, C., Hao, Y., Zhao, J., Zhang, L., Fan, R., Liu, Y., Li, R., Chen, Z., Zhang, T., Chen, S., Ma, J., Liu, S., Peng, X., Duan, S. Tags: Myocardial cardiomyopathy disease, Valvular heart disease, Clinical Studies, Acute Cerebral Hemorrhage, Cerebral Venous Thrombosis Clinical Sciences Source Type: research

Noncompaction Cardiomyopathy and Stroke: Case Report and Literature Review
To describe a rare case of isolated noncompaction cardiomyopathy and stroke and to review the medical literature on noncompaction cardiomyopathy.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2015 Category: Neurology Authors: Ashish Kulhari, Nikhil Kalra, Cathy Sila Tags: Case Report Source Type: research

Acute ischemic stroke due to Left Ventricular Noncompaction Syndrome from a novel mutation of the Lamin A/C gene (P2.254)
Conclusion: LVNC is a risk factor for cardioembolic ischemic stroke particularly in young patients that is not well known. Patients with suspected LVNC by echocardiography should undergo cardiac MRI for confirmation and genetic testing in particular for mutations in the LMNA gene. The prognosis of those with LVNC syndrome is poor; most worsen over time and need ultimately transplantation. Close follow-up is required.Disclosure: Dr. Vongveeranonchai has nothing to disclose. Dr. Mittal has nothing to disclose. Dr. Ramos Estebanez has nothing to disclose. Dr. DeGeorgia has received personal compensation for activities with OS...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Vongveeranonchai, N., Mittal, S., Ramos Estebanez, C., De Georgia, M. Tags: Cerebrovascular Disease and Interventional Neurology: Genetics and Stroke Source Type: research

Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events (P6.241)
Conclusion- Patient’s knowledge about OAT was suboptimal. The findings support the need for educational interventions to improve the knowledge regarding oral anticoagulation therapy, and thereby achieve an appropriate and safe secondary prevention of stroke.Disclosure: Dr. Bhatia has nothing to disclose. Dr. Alphonsa has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bhatia, R., Alphonsa, A., Sharma, K., Sharma, G. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

G.P.157: Clinical and pathological features associated with mutations in MICU1
We present the clinical/pathological features in a cohort of 18 patients. Patients presented between birth and 8years with a mild, relatively static, proximal myopathy associated with high Creatinine Kinase (2000–10,000iu/L), learning difficulties and frequent microcephaly. At follow up (5–28yrs), all remained ambulant but variable extrapyramidal symptoms had developed in the majority by the end of the 1st decade. Other features suggestive of mitochondrial dysfunction included peripheral neuropathy, icthyosis, stroke like episodes, episodic weakness, ataxia and cataracts. Cardiomyopathy was not seen. Serum and CSF lact...
Source: Neuromuscular Disorders - September 4, 2014 Category: Neurology Authors: A.M. Childs, K. Pysden, H. Roper, G. Chow, E.H. Niks, M. Kriek, P.F. Chinnery, D. Lewis-Smith, M. Duchen, G. Szabadkai, C. Logan, E. Sheridan, C. Sewry, F. Muntoni Source Type: research

CNS-disease affecting the heart: Brain–heart disorders
Abstract: There are a number of hereditary and non-hereditary central nervous system (CNS) disorders, which directly or indirectly affect the heart (brain–heart disorders). The most well-known of these CNS-disorders are epilepsy, stroke, subarachanoid bleeding, bacterial meningitis, and head injury. In addition, a number of hereditary and non-hereditary neurodegenerative disorders may impair cardiac functions. Affection of the heart may manifest as arrhythmias, cardiomyopathy, or autonomic dysfunction. Rarer cardiac complications of CNS disorders include heart failure, systolic or diastolic dysfunction, myocardial infarc...
Source: Journal of the Neurological Sciences - July 10, 2014 Category: Neurology Authors: Josef Finsterer, Karim Wahbi Tags: Reviews Source Type: research

Stroke in Children with Human Immunodeficiency Virus in Botswana: A Report of Six Cases (P4.303)
CONCLUSIONS: The risk of stroke appears to be increased in children with HIV, though further controlled studies are necessary to further investigate this. Etiologies for stroke in children with HIV includes HIV vasculopathy, HIV cardiomyopathy, and opportunistic infections. Evaluation should include head imaging with vascular imaging, MRI with MRA if possible, and CT. The utility of lumbar puncture and hypercoaguability workup in this population needs to be investigated further. Given the difficulties of monitoring anticoagulation in this setting, low dose aspirin is a reasonable first line treatment.Disclosure: Dr. Khuran...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Khurana, E., Bearden, D. Tags: NeuroAIDS Source Type: research

Children with Friedreich Ataxia Undergoing Spinal Fusion Are at Risk for Arrhythmias (P2.037)
CONCLUSIONS: Scoliosis surgery is common amongst hospitalized children with FA, but these comprise a small proportion of all children who undergo spinal fusion. Arrhythmias are more common in FA children undergoing spinal fusion; other comorbidities are similar to non-FA children. FA does not affect length of stay, mean hospital charges, and overall mortality in hospitalizations involving spinal fusion. The increased burden of arrhythmias in FA supports cardiac assessment for children with FA and scoliosis.Disclosure: Dr. Lin has nothing to disclose. Dr. Lynch has received personal compensation for activities with Retrotap...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Lin, K., Lynch, D., Flynn, J., Rossano, J. Tags: Movement Disorders: Friedreich ' s and Other Inherited Ataxias Source Type: research