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Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality risk
CONCLUSION: The detrimental associations of poor sleep with all-cause and cause-specific mortality risks are exacerbated by low PA, suggesting likely synergistic effects. Our study supports the need to target both behaviours in research and clinical practice.PMID:34187783 | DOI:10.1136/bjsports-2021-104046
Source: British Journal of Sports Medicine - June 30, 2021 Category: Sports Medicine Authors: Bo-Huei Huang Mitch J Duncan Peter A Cistulli Natasha Nassar Mark Hamer Emmanuel Stamatakis Source Type: research

Sleep duration and health outcomes: an umbrella review
CONCLUSION: Inappropriate sleep duration is a risk factor for developing non-cancer conditions. Decreasing and increasing sleep hours towards extreme sleep durations are associated with poor health outcomes.PMID:34435311 | DOI:10.1007/s11325-021-02458-1
Source: Sleep and Breathing - August 26, 2021 Category: Sleep Medicine Authors: Jin Li Dehong Cao Yin Huang Zeyu Chen Ruyi Wang Qiang Dong Qiang Wei Liangren Liu Source Type: research

The global burden of disease attributable to ambient fine particulate matter in 204 countries and territories, 1990-2019: A systematic analysis of the Global Burden of Disease Study 2019
Ecotoxicol Environ Saf. 2022 May 4;238:113588. doi: 10.1016/j.ecoenv.2022.113588. Online ahead of print.ABSTRACTUnderstanding the spatio-temporal patterns of the disease burden attributable to ambient PM2.5 across the world is essential for the prevention of related diseases, as well as ambient PM2.5 control. Following the framework and methodology of the Global Burden of Disease Study (GBD) in 2019, the global, regional, and national data on ambient PM2.5-attributable death and disability-adjusted life years (DALYs), and the age-standardized rates of mortality (ASMR) and disability-adjusted life years (ASDR) were summariz...
Source: Cancer Control - May 7, 2022 Category: Cancer & Oncology Authors: Shaowei Sang Chong Chu Tongchao Zhang Hui Chen Xiaorong Yang Source Type: research

Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality risk
Conclusion The detrimental associations of poor sleep with all-cause and cause-specific mortality risks are exacerbated by low PA, suggesting likely synergistic effects. Our study supports the need to target both behaviours in research and clinical practice.
Source: British Journal of Sports Medicine - June 16, 2022 Category: Sports Medicine Authors: Huang, B.-H., Duncan, M. J., Cistulli, P. A., Nassar, N., Hamer, M., Stamatakis, E. Tags: Editor's choice, Press releases, BJSM Original research Source Type: research

Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM < sub > 2.5 < /sub > , BC, NO < sub > 2 < /sub > , and O < sub > 3 < /sub > : An Analysis of European Cohorts in the ELAPSE Project
CONCLUSIONS: Long-term exposure to PM2.5, NO2, and BC was positively associated with natural-cause and cause-specific mortality in the pooled cohort and the administrative cohorts. Associations were found well below current limit values and guidelines for PM2.5 and NO2. Associations tended to be supralinear, with steeper slopes at low exposures with no indication of a threshold. Two-pollutant models documented the importance of characterizing the ambient mixture with both NO2 and PM2.5. We mostly found negative associations with O3. In two-pollutant models with NO2, the negative associations with O3 were attenuated to esse...
Source: Cancer Control - September 15, 2022 Category: Cancer & Oncology Authors: Brunekreef Bert Strak Maciej Chen Jie J Andersen Zorana Atkinson Richard Bauwelinck Mariska Bellander Tom Boutron Marie-Christine Brandt J ørgen Carey Iain Cesaroni Giulia Forastiere Francesco Fecht Daniela Gulliver John Hertel Ole Hoffmann Barbara de Ho Source Type: research

Neurovascular Manifestations of Iron-Deficient Anemia: Narrative Review and Practical Reflections through a Teaching Case
Conclusions: IDA is a common but treatable condition that, independently or synergically, may increase the risk of thrombotic events. The diagnostic and therapeutic approach has not yet been defined, and each case should be individually addressed in a pragmatic clinical road map.PMID:36294407 | DOI:10.3390/jcm11206088
Source: Clinical Lung Cancer - October 27, 2022 Category: Cancer & Oncology Authors: Marialuisa Zedde Giacomo Portaro Laura Ferri Francesco Cavallieri Manuela Napoli Claudio Moratti Fabrizio Piazza Franco Valzania Rosario Pascarella Source Type: research

Daily aspirin 'reduces cancer risk', study finds
Conclusion While the findings on aspirin and cancer show promise, it is not clear that the results are reliable from the methods reportedly used to compile this review. This is because it included studies of varying design and quality, with much of the evidence coming from observational studies, which, while useful, cannot be totally relied on to test the effectiveness of healthcare interventions. It's not clear how the studies included in the review were chosen and whether others on the same topic were excluded. It is also not clear whether or not this was a systematic review, where studies are rigorously appraised for ...
Source: NHS News Feed - August 6, 2014 Category: Consumer Health News Tags: Cancer Medication Source Type: news

Abstract B84: Increasing disparities in breast cancer mortality for young black women in the U.S. from 1979-2010
Conclusions: Though mortality rates have declined over the past 30 years for women under 50, significant disparities in the two leading causes of death, cancer and CVD, remain. The persistence of disparities across diseases highlights the need to focus on improving health outcomes broadly, in addition to disease centered approaches, in order to prevent premature deaths among young women. The breast cancer mortality rate was two times greater among black women younger than 50 compared to white women, indicating a more profound disparity in younger women than older women. Furthermore, while relative disparities have decrease...
Source: Cancer Epidemiology Biomarkers and Prevention - November 13, 2014 Category: Cancer & Oncology Authors: McCarthy, A. M., Yang, J., Armstrong, K. Tags: Screening and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research

Inflammatory Claims About Inflammation
We all appreciate the elegance of simple solutions to complex problems. But we know too that simplicity can often masquerade as truth, hiding a more nuanced reality. Such is the case with inflammation, where pseudoscience, exaggerated claims, false promises, and dangerous oversimplification have dominated for too long. Here is a typical missive: "Inflammation controls our lives. Have you or a loved one dealt with pain, obesity, ADD/ADHD, peripheral neuropathy, diabetes, heart disease, stroke, migraines, thyroid issues, dental issues, or cancer? If you answered yes to any of these disorders you are dealing with inflammatio...
Source: Science - The Huffington Post - May 29, 2015 Category: Science Source Type: news

Reduction of risk of dying from tobacco-related diseases after quitting smoking in Italy.
CONCLUSIONS: Estimates of risk reduction by quitting smoking are useful to provide a sounder scientific basis for public health messages and clinical advice. PMID: 26108248 [PubMed - as supplied by publisher]
Source: Tumori - June 26, 2015 Category: Cancer & Oncology Tags: Tumori Source Type: research

Are high-speed cyclists at risk from air pollution?
Conclusion This study may be of interest to those in the field of sports medicine. It calculates the speed that walkers, joggers and cyclists may travel at to minimise the pollution they potentially inhale. It also finds that these values turn out to be those that many pedestrians and cyclists would travel at in any case. And, somewhat unsurprisingly, this speed would go down as you go uphill because of the increased effort and breathing rate required. Fitter people who run or cycle fast for sport are, however, naturally likely to exceed this minimum speed requirement, both on the flat and speed gradients. This could pot...
Source: NHS News Feed - October 31, 2016 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Source Type: news

Tar level of cigarettes smoked and risk of smoking-related diseases.
CONCLUSIONS: Despite evidence that smokers substantially compensate for reduced cigarette yields, the results clearly show lower risks in lower tar smokers. Limitations of the evidence are discussed, but seem unlikely to affect this conclusion. PMID: 29488428 [PubMed - as supplied by publisher]
Source: Inhalation Toxicology - March 2, 2018 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Current Tobacco Smoking, Quit Attempts, and Knowledge About Smoking Risks Among Persons Aged ≥15 Years - Global Adult Tobacco Survey, 28 Countries, 2008-2016.
Abstract Each year, tobacco use causes approximately 7 million deaths worldwide, including approximately 6 million among tobacco users and an estimated 890,000 among nonsmokers exposed to secondhand smoke (1). Tobacco use is a leading preventable cause of disease globally and has been determined to cause adverse health outcomes such as coronary heart disease, stroke, and multiple types of cancer, including lung cancer (2-4). Approximately 80% of the world's 1.1 billion tobacco smokers reside in low- and middle-income countries (4). Some persons do not fully understand the health risks associated with tobacco smoki...
Source: MMWR Morb Mortal Wkl... - September 28, 2018 Category: Epidemiology Authors: Ahluwalia IB, Smith T, Arrazola RA, Palipudi KM, Garcia de Quevedo I, Prasad VM, Commar A, Schotte K, Garwood PD, Armour BS Tags: MMWR Morb Mortal Wkly Rep Source Type: research