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Glutathione S-Transferase Gene Polymorphisms are Associated with an Improved Treatment Response to Cisplatin-Based Chemotherapy in Patients with Non-Small Cell Lung Cancer (NSCLC): A Meta-Analysis.
CONCLUSIONS Meta-analysis showed that the GG genotype of GSTP1 IIe105Val and the null GSTM1 genotype were associated with an improved treatment response to cisplatin-based chemotherapy in patients with NSCLC, especially in East-Asian patients.
PMID: 30341887 [PubMed - in process]
Source: Medical Science Monitor - October 22, 2018 Category: Research Tags: Med Sci Monit Source Type: research
Common mental disorders in Taiwanese consumers of commercial low-dose computed tomography lung cancer screening: Comparison with a nationally representative sample
ConclusionCommercial LDCT lung cancer screening users may have a positive association with probable CMDs compared to the general population. Screening programs should consider including criteria and providing psychoeducation to improve the physical and mental outcomes of participants.Clinical trial registrationPurely observational studies (those in which the assignment of the medical intervention is not at the discretion of the investigator) do not require registration.
Source: Journal of the Formosan Medical Association - November 29, 2019 Category: General Medicine Source Type: research
A mapping study of ensemble classification methods in lung cancer decision support systems
AbstractAchieving a high level of classification accuracy in medical datasets is a capital need for researchers to provide effective decision systems to assist doctors in work. In many domains of artificial intelligence, ensemble classification methods are able to improve the performance of single classifiers. This paper reports the state of the art of ensemble classification methods in lung cancer detection. We have performed a systematic mapping study to identify the most interesting papers concerning this topic. A total of 65 papers published between 2000 and 2018 were selected after an automatic search in four digital ...
Source: Medical and Biological Engineering and Computing - July 2, 2020 Category: Biomedical Engineering Source Type: research
High Value Care in Cancer Surveillance and Screening: Evaluating an e-Curriculum for Primary Care Providers
ConclusionThis curriculum provided concise, effective education for PCPs on 3 common cancers. Limitations include content breadth and lack of data reflecting physician ordering patterns. Curricular strengths include its accessibility, immediate feedback, and effectiveness, with a significant improvement in immediate and delayed post-test knowledge. Given a lack of increased confidence to provide cancer surveillance, PCPs should rely on electronic medical record tools and other resources to guide appropriate surveillance care.
Source: Journal of Cancer Education - March 15, 2021 Category: Cancer & Oncology Source Type: research
Second primary cancers: a retrospective analysis of real world data using the enhanced medical research engine ConSoRe in a French comprehensive cancer center
ConclusionThe data mining tool ConSoRe contributes to access to real world data, and to better characterize patients with SPC. Expanding such approach to any comprehensive center will allow a global overview of the follow-up of patients with cancer, and help to improve long-term management and adapt surveillance.
Source: International Journal of Clinical Oncology - June 5, 2021 Category: Cancer & Oncology Source Type: research
Association between Albumin, Total Bilirubin, and Uric Acid Serum Levels and the Risk of Cancer: A Prospective Study in a Korean Population
CONCLUSION: The findings of this study support the role of antioxidants in carcinogenesis. Future large-cohort studies are needed to confirm the predictive value of albumin, UA, and total bilirubin levels in each type of cancer.PMID:34427064 | DOI:10.3349/ymj.2021.62.9.792
Source: Yonsei Medical Journal - August 24, 2021 Category: Universities & Medical Training Authors: Ye Rim Kim Chang Kyun Choi Young Hoon Lee Seong Woo Choi Hye Yeon Kim Min Ho Shin Sun Seog Kweon Source Type: research
Driver and actionable mutations in younger patients with lung cancer - are we searching properly?
CONCLUSION: We detected very frequent driver and potentially actionable alterations in young patients with lung cancer. This suggests different mechanisms of carcinogenesis in these patients and indicates that they might benefit more from a specific approach than older lung cancer patients.PMID:37009714 | DOI:10.5507/bp.2023.012
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - April 3, 2023 Category: Biomedical Science Authors: Monika Bratova Kristian Brat Zdenek Pavlovsky Jiri Sana Ondrej Slaby Source Type: research
Global burden and trends of lung cancer incidence and mortality
CONCLUSIONS: The burden of lung cancer is still unsatisfactory, especially in developing countries like China. Considering the effectiveness of tobacco control and screening in developed countries, such as the USA, there is a need to strengthen health education, accelerate the establishment of tobacco control policies and regulations, and improve early cancer screening awareness to reduce the future burden of lung cancer.PMID:37027426 | DOI:10.1097/CM9.0000000000002529
Source: Chinese Medical Journal - April 7, 2023 Category: General Medicine Authors: Chao Li Shaoyuan Lei Li Ding Yan Xu Xiaonan Wu Hui Wang Zijin Zhang Ting Gao Yongqiang Zhang Lin Li Source Type: research
Driver and actionable mutations in younger patients with lung cancer - are we searching properly?
CONCLUSION: We detected very frequent driver and potentially actionable alterations in young patients with lung cancer. This suggests different mechanisms of carcinogenesis in these patients and indicates that they might benefit more from a specific approach than older lung cancer patients.PMID:37009714 | DOI:10.5507/bp.2023.012
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - April 3, 2023 Category: Biomedical Science Authors: Monika Bratova Kristian Brat Zdenek Pavlovsky Jiri Sana Ondrej Slaby Source Type: research
