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Leading Health Mistakes Women Make In Their 30s
Credit For many women, turning 30 marks the real beginning of adulthood. You're established in a career, and maybe in a relationship. You might be thinking about starting a family. You feel pretty good about yourself, and all the health indiscretions of your 20s (remember those all-night parties and how you still managed to make it into work the next day?) haven't taken much of a health toll. But let's face it, ages 30 to 39 are prime time. All in all, the 30s are a very positive time for health, but it's also the time you have to start developing excellent habits as an investment in the future, says Dr. Debra DeJoseph,...
Source: Healthy Living - The Huffington Post - August 17, 2016 Category: Consumer Health News Source Type: news

Man with Ataxia and Aortic Mass
A 59-year-old man with a history of testicular cancer in remission and dyslipidemia undergoing outpatient evaluation for ataxia was referred to our emergency department after a magnetic resonance imaging scan of the brain led to a diagnosis of a cerebellar stroke and comprehensive transthoracic echocardiogram visualized a mass in the proximal ascending aorta. Upon arrival to the emergency department, point-of-care echocardiography confirmed the presence of a mobile echogenic 2.0-  × 1.9-cm mass distal to the aortic valve.
Source: The Journal of Emergency Medicine - November 13, 2016 Category: Emergency Medicine Authors: Michael R. Ehmann, Geoffrey S. Kelly Tags: Visual Diagnosis in Emergency Medicine Source Type: research

The pain of chronic loneliness can be detrimental to your health
The changes came so gradually that, for a long time, Paula Dutton didn ’t realize she was in trouble. This was just modern life, after all — the cross-country distance from her close-knit family in Philadelphia, the end of a 10-year marriage, the death of one parent and then the other. By the time Dutton retired from her job, she was lonely to a degree that shocked and frightened her.“I just suddenly realized I was all alone and had no one around me and no one I could turn to,” says Dutton, now 71. “I had a lot of pity parties, I can tell you — and with all kinds of anxiety and depression. And I worked myself i...
Source: UCLA Newsroom: Health Sciences - December 22, 2016 Category: Universities & Medical Training Source Type: news

The Medical Emergency Of Otto Warmbier
All that the doctors who treated Cincinnati, Ohio resident Otto Warmbier knew is what they had seen or maybe read in the news. They knew he had just been released on June 13 from imprisonment in North Korea where he had been held by for more than 17 months. He had been sentenced in March 2016 to 15 years of hard labor for allegedly removing a propaganda poster from a wall at a Pyongyang hotel where he had been staying. The University of Virginia honors student had been visiting the authoritarian state during a five-day trip with a group called Young Pioneer Tours, which is a group out of China – an important note. Ot...
Source: Healthy Living - The Huffington Post - June 22, 2017 Category: Consumer Health News Source Type: news

Chapter 37 Overview of neuroradiology
Publication date: 2017 Source:Handbook of Clinical Neurology, Volume 145 Author(s): Elna-Marie Larsson, Johan Wikström Neuroradiology with computed tomography (CT) and magnetic resonance imaging (MRI) is essential for the initial evaluation of patients with a clinical suspicion of brain and spine disorders. Morphologic imaging is required to obtain a probable diagnosis to support the treatment decisions in pre- and perinatal disorders, vascular diseases, traumatic injuries, metabolic disorders, epilepsy, infection/inflammation, neurodegenerative disorders, degenerative spinal disease, and tumors of the central nervous sy...
Source: Handbook of Clinical Neurology - October 4, 2017 Category: Neurology Source Type: research

The Pattern of significant lesions found in computerized tomography scan of recurrent seizure patients at a center in Enugu, Nigeria
Conclusion: Computed tomography scan has a high diagnostic yield, especially in elderly patients with recurrent generalized seizures. Brain tumors, encephalomalacia, and HCP are most common causes of recurrent seizures in the adults.
Source: Nigerian Journal of Clinical Practice - December 1, 2017 Category: Rural Health Authors: AB Ezeala-Adikaibe SC Ohaegbulam CA Ndubuisi Source Type: research

MADCO-Accelerated Multidimensional Diffusion MRI
The marginal distribution constrained optimization (MADCO) methodology is disclosed wherein a 2D (or higher-dimensional) spectrum is estimated from initial 1D marginal distribution data. These 1D marginal distributions are used as constraints in the reconstruction of the 2D spectra. MADCO accelerates and improves the reconstruction of multidimensional NMR relaxation/diffusion spectra, making it suitable for MRI applications on a voxel-by-voxel basis by vastly reducing the amount of data acquired and data necessary for creating MRI images.NIH Ref. No.: E-173-2016Advantages: • Disruptive technologies can positive...
Source: NIH OTT Licensing Opportunities - December 7, 2017 Category: Research Authors: ajoyprabhu3 Source Type: research

Predictor variables of abnormal imaging findings of syncope in the emergency department
ConclusionsOur data offer that the identification of predictor variables has a potential to decrease the routine use of head CT and MRI in patients admitting to the ED with syncope.
Source: International Journal of Emergency Medicine - March 12, 2018 Category: Emergency Medicine Source Type: research

Measuring non-parametric distributions of intravoxel mean diffusivities using a clinical MRI scanner
Publication date: Available online 13 October 2018Source: NeuroImageAuthor(s): Alexandru V. Avram, Joelle E. Sarlls, Peter J. BasserAbstractWe measure spectra of water mobilities (i.e., mean diffusivities) from intravoxel pools in brain tissues of healthy subjects with a non-parametric approach. Using a single-shot isotropic diffusion encoding (IDE) preparation, we eliminate signal confounds caused by anisotropic diffusion, including microscopic anisotropy, and acquire in vivo diffusion weighted images (DWIs) over a wide range of diffusion sensitizations. We analyze the measured IDE signal decays using a regularized invers...
Source: NeuroImage - October 13, 2018 Category: Neuroscience Source Type: research

In vivo evaluation of 11CTMI, a COX-2 selective PET tracer, in baboons.
The objective of this study is to evaluate [11C]TMI, a selective COX-2 inhibitor (Ki ≤ 1 nM) in nonhuman primates using PET imaging. PET imaging in baboons showed that [11C]TMI penetrates the blood brain barrier (BBB) and accumulates in brain in a somewhat heterogeneous pattern. Metabolite analyses indicated that [11C]TMI undergoes no significant metabolism of parent tracer in the plasma for baseline scans, however a relative faster metabolism was found for blocking scan. All the tested quantification approaches provide comparable tracer total distribution volume (VT) estimates in the range of 3.2-7 (mL/cm3). We ...
Source: Bioorganic and Medicinal Chemistry Letters - October 31, 2018 Category: Chemistry Authors: Kumar JSD, Zanderigo F, Prabhakaran J, Rubin-Falcone H, Parsey RV, Mann JJ Tags: Bioorg Med Chem Lett Source Type: research

Non-Invasive In Vivo MRI Method to Image Salient Features of Axons and Nerves
The invention from Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) provides a non-invasive, painless means for measuring microanatomical features of Nerve and Axon Diameter Distribution (ADD) to image the Central and Peripheral Nervous Systems (CNS and PNS). ADD is altered in abnormal development (e.g., autism), in neurodegenerative processes (e.g., aging, alcoholism, Alzheimer ’s disease) and diseases such as ALS (Lou Gehrig’s disease). U.S. patent 7,643,863, related to this invention, consists of a novel diffusion Magnetic Resonance Imaging (MRI) experiment and modeling framew...
Source: NIH OTT Licensing Opportunities - November 14, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research

Longitudinal association between brain volume change and gait speed in a general population.
CONCLUSION: In a four-year longitudinal study among 767 well-functioning community-dwelling healthy participants from a general population, we observed a significant association between brain volume changes and gait speed. PMID: 30611726 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - January 3, 2019 Category: Geriatrics Authors: Lee S, Kim EY, Shin C Tags: Exp Gerontol Source Type: research

Poor Sleep Linked To Dangerous Plaque Buildup In Arteries
By Sandee LaMotte, CNN (CNN) — Here’s another reason why getting a good night’s sleep should be on your must-do list: Sleeping fewer than six hours a night or waking frequently raises your risk of developing damaging plaque in arteries throughout your body, not just your heart. Previous research has shown poor sleep to be strongly associated with coronary heart disease, but “This is the first study to show that objectively measured sleep is independently associated with atherosclerosis throughout the body,” José Ordovás, director of nutrition and genomics at the Jean Mayer USDA Human Nutriti...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health CNN Heart Disease Sleep Tufts University Source Type: news

Cancers, Vol. 11, Pages 111: A Review on a Deep Learning Perspective in Brain Cancer Classification
uca Saba Jasjit S. Suri A World Health Organization (WHO) Feb 2018 report has recently shown that mortality rate due to brain or central nervous system (CNS) cancer is the highest in the Asian continent. It is of critical importance that cancer be detected earlier so that many of these lives can be saved. Cancer grading is an important aspect for targeted therapy. As cancer diagnosis is highly invasive, time consuming and expensive, there is an immediate requirement to develop a non-invasive, cost-effective and efficient tools for brain cancer characterization and grade estimation. Brain scans using magnetic resonanc...
Source: Cancers - January 18, 2019 Category: Cancer & Oncology Authors: Gopal S. Tandel Mainak Biswas Omprakash G. Kakde Ashish Tiwari Harman S. Suri Monica Turk John R. Laird Christopher K. Kwaku A. Annabel A. Ankrah N. N. Khanna B. K. Madhusudhan Luca Saba Jasjit S. Suri Tags: Review Source Type: research