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Total 28027 results found since Jan 2013.

Breastfeeding and Childhood Leukemia Incidence
This meta-analysis of articles researching the association between breastfeeding and childhood leukemia reports that breastfeeding for 6 months or more may help lower childhood leukemia incidence.
Source: JAMA Pediatrics - June 1, 2015 Category: Pediatrics Source Type: research

Estimating Health Benefits And Lifetime Economic Cost-Savings From Promoting Breastfeeding To Prevent Childhood Leukemia In The United States
No study has estimated the potential health benefits of breastfeeding on childhood leukemia using the Healthy People (HP) 2020 national goals. We estimated expected life-years (LYs) saved, lifetime medical cost-savings and productivity gained from the reduction of childhood leukemia from breastfeeding under three scenarios: a) ever breastfed, b) breastfed at 6 months, and c) breastfed at 12 months.
Source: Value in Health - April 30, 2016 Category: Global & Universal Authors: D Ekwueme, M Hung, G Guy, SH Rim Source Type: research

Breastfeeding: debunking preconceptions and removing barriers
Breastfeeding has benefits for both the mother and child and should be encouraged and supported by healthcare professionals where possible. Fully breastfeeding an infant for 6  months has been shown to carry a lower incidence of gastrointestinal illness, sudden infant death syndrome, respiratory illnesses and childhood leukaemia. For the mother, there is a reduction in breast cancer, hypertension and type 2 diabetes. Prescribing decisions in the breastfed mother should b e an individualized decision and take into account the risks and benefits of treatment.
Source: Obstetrics, Gynaecology and Reproductive Medicine - June 8, 2022 Category: OBGYN Authors: Sarah Barnes, Sophie Bennett, Shreelata Datta Tags: Case-based learning Source Type: research

Modelling the cost-effectiveness of human milk and breastfeeding in preterm infants in the United Kingdom
ConclusionsThis analysis established that increasing the use of human milk in NICUs in the UK would lead to cost savings to the NHS. More research is needed on the medium and long term health and economic outcomes associated with breastfeeding preterm infants, and the differences between mother ’s own and donor breast milk.
Source: Health Economics Review - November 30, 2016 Category: Global & Universal Source Type: research

Relationship Between State-Level Google Online Search Volume and Cancer Incidence in the United States: Retrospective Study
Conclusions: Cancer incidence is correlated with online search volume at the state level. Search patterns were temporally associated with cancer awareness months and celebrity announcements. Online searches reflect public awareness. Advancing understanding of online search patterns could augment traditional epidemiologic surveillance, provide opportunities for targeted patient engagement, and allow public information campaigns to be evaluated in ways previously unable to be measured.
Source: Journal of Medical Internet Research - January 8, 2018 Category: General Medicine Authors: Charles A. Phillips Allison Barz Leahy Yimei Li Marilyn M. Schapira L. Charles Bailey Raina M. Merchant Source Type: research

Is a Matched Unrelated Donor Search Needed for All Allogeneic Transplant Candidates?
ConclusionsRace, haplotype frequency and disease status at the time of MUD search influence probability to identify a MUD and receive a transplant. Patients with low likelihood to receive a MUD transplant may proceed to a haploidentical transplant as soon as indicated, as this approach does not appear to compromise transplant outcomes.DisclosuresKonopleva: Stemline Therapeutics: Research Funding. Oran: AROG pharmaceuticals: Research Funding; Celgene: Consultancy, Research Funding; ASTEX: Research Funding. Champlin: Otsuka: Research Funding; Sanofi: Research Funding.
Source: Blood - November 21, 2018 Category: Hematology Authors: Ciurea, S. O., Borges Bittencourt, M. C., Milton, D. R., Cao, K., Kongtim, P., Rondon, G., Chen, J., Konopleva, M. Y., Ramos Perez, J. M., Elshazly, M., Aljadayeh, M., Alvarez, M., Im, J. S., Alatrash, G., Mehta, R. S., Popat, U., Bashir, Q., Oran, B., Ho Tags: 732. Clinical Allogeneic Transplantation: Results: Poster II Source Type: research

The search for cis-regulatory driver mutations in cancer genomes.
Authors: Poulos RC, Sloane MA, Hesson LB, Wong JW Abstract With the advent of high-throughput and relatively inexpensive whole-genome sequencing technology, the focus of cancer research has begun to shift toward analyses of somatic mutations in non-coding cis-regulatory elements of the cancer genome. Cis-regulatory elements play an important role in gene regulation, with mutations in these elements potentially resulting in changes to the expression of linked genes. The recent discoveries of recurrent TERT promoter mutations in melanoma, and recurrent mutations that create a super-enhancer regulating TAL1 expression...
Source: Oncotarget - September 13, 2015 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Proteomics Versus Clinical Data and Stochastic Local Search Based Feature Selection for Acute Myeloid Leukemia Patients ’ Classification
This study proposes a meta-heuristic framework using stochastic local search (SLS) combined with random forest (RF) where the aim is to specify the most important genes and proteins leading to the best classification of Acute Myeloid Leukemia (AML) patients. First we use a stochastic local search meta-heuristic as a feature selection technique to select the most significant proteins to be used in the classification task step. Then we apply RF to classify new patients into their corresponding classes. The evaluation technique is to run the RF classifier on the training data to get a model. Then, we apply this model on the t...
Source: Journal of Medical Systems - June 4, 2018 Category: Information Technology Source Type: research

ATP-Binding Cassette transporters' gene expression in pediatric patients with acute leukemia; a comprehensive analysis of published reports through PubMed search engine.
Authors: Mehrvar N, Akbari ME, Rezvany MR, Abolghasemi H, Saberynejad J, Mehrvar A, Faranoush M, Keramatinia AA, Shekarriz-Foumani R, Movafagh A Abstract Multidrug resistance based on ABC transporters' gene expression is one of the most important health challenges through chemotherapy of patients. This resistance can cause relapse or treatment failure. The goal of this conducted study was to evaluate the results of published reports which considered ABC transporters' gene expression in pediatric patients with acute leukemia. PubMed as a free search engine was chosen. The following Mesh terms were used as: "ATP-bind...
Source: Cellular and Molecular Biology - March 13, 2019 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

A Case of Acute Leukemia Following Remission of COVID-19 Infection; an Urge to Search for a Probable Association
Arch Acad Emerg Med. 2021 Jul 24;9(1):e51. eCollection 2021.ABSTRACTMany aspects of Covid-19 infection, especially its complications and long-term health consequences are still unknown. Several reports concerning concomitant covid-19 infection and hematological disorders have been published recently. We aim to present a unique case of acute myeloid leukemia in a 61-year-old man with a previous history of covid-19 infection 40 days ago, with near complete resolution of signs and symptoms attributable to covid-19 infection. After 3 weeks, the patient presented again with progressive weakness, nausea, vomiting, and epigastric...
Source: Accident and Emergency Nursing - August 18, 2021 Category: Emergency Medicine Authors: Seyyed Mojtaba Nekooghadam Afshin Moradi Kimia Karimi Toudeshki Mehdi Pishgahi Source Type: research

CD177 Expression on Neutrophils: In Search of a Clonal Assay for Myeloid Neoplasia by Flow Cytometry.
Conclusions: Skewed low neutrophil CD177(%) is highly associated with clonal myeloid disorders, particularly myelodysplasia, and may be useful for detecting clonal myeloid disorders. PMID: 24124144 [PubMed - as supplied by publisher]
Source: American Journal of Clinical Pathology - October 15, 2013 Category: Pathology Authors: Meyerson HJ, Osei E, Schweitzer K, Blidaru G, Edinger A, Balog A Tags: Am J Clin Pathol Source Type: research

A comparative study of Hasford score and Sokal index in prognostication of the novo chronic myeloid leukemia patients and a search for new prognostic markers.
Conclusions: This study shows that Hasford score predicts survival of the patients better than Sokal index. However, multicentric study over a large population is needed to give the final verdict. PMID: 24152497 [PubMed - in process]
Source: Indian Journal of Pathology and Microbiology - July 1, 2013 Category: Pathology Authors: Sinha SK, Sinha S, Mandal PK, Bhattacharyya NK, Pandey A, Gupta P Tags: Indian J Pathol Microbiol Source Type: research