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Total 1172 results found since Jan 2013.
Research Progress and New Perspectives of Anticancer Effects of Emodin
In conclusion, emodin represents a promising natural compound with potent anticancer properties, and its potential as a therapeutic agent for cancer treatment warrants further investigation. This review provides a comprehensive overview of the current research progress and new perspectives on emodin's anticancer effects, which may facilitate the development of novel therapeutic strategies for cancer treatment.PMID:37732372 | DOI:10.1142/S0192415X23500787
Source: The American Journal of Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Wu Liu Eskandar Qaed Yuelin Zhu Wenzhang Tian Yizhen Wang Le Kang Xiaodong Ma Zeyao Tang Source Type: research
Red cell distribution width-a potential prognostic indicator for colorectal cancer patients after radical resection in China
CONCLUSIONS: Our findings demonstrate that preoperative RDW may represent a simple and powerful prognostic factor for CRC patients after radical resection. Integrating RDW into clinical practice may better inform the prognosis and optimize therapeutic approaches for patients with CRC.PMID:37720452 | PMC:PMC10502564 | DOI:10.21037/jgo-23-54
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Weiwei Zhao Xuefang Shen Qing Hua Liu Yang Ru Zhou Changming Zhou Pingbo Xu Source Type: research
Correlation between High Incidence of Colorectal Neoplastic Polyps and High-risk Adenomas in Patients with Diabetes Mellitus: A Retrospective Study
CONCLUSION: This study demonstrated that patients with DM, age ≥ 50 years, male gender, alcohol consumption, and a first-degree relative with a history of CRC should undergo regular endoscopic screening and colonic polypectomy.PMID:37711116 | DOI:10.2174/1871530323666230913105743
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Endocrinology Authors: Chuan-Yu Zheng Wa Zhong Ji-Hao Xu Yu-Hong Yuan Nai-Zhao Chen Wei-Ling Liang Qi-Kui Chen Yu Lai Source Type: research
A genetic variant in the immune-related gene ERAP1 affects colorectal cancer prognosis
CONCLUSION: The rs71630754 could influence the prognosis of CRC patients by regulating the expression of the immune-related gene ERAP1.PMID:37690994 | DOI:10.1097/CM9.0000000000002845
Source: Chinese Medical Journal - September 10, 2023 Category: General Medicine Authors: Danyi Zou Yimin Cai Meng Jin Ming Zhang Yizhuo Liu Shuoni Chen Shuhui Yang Heng Zhang Xu Zhu Chaoqun Huang Ying Zhu Xiaoping Miao Yongchang Wei Xiaojun Yang Jianbo Tian Source Type: research
Interventional effects of oral microecological agents on perioperative indicators of colorectal cancer: a meta-analysis
CONCLUSION: By increasing the number of beneficial flora such as Lactobacillus and Bifidobacterium and decreasing the number of harmful flora such as Escherichia coli, the micro-ecological preparation group is beneficial in improving the ecological dysregulation in colorectal cancer patients receiving different treatments in the perioperative period. The microecological preparation group was able to reduce many types of adverse drug reactions, such as infections and gastrointestinal discomfort, compared to the control group. The microecological agents also reduced inflammatory responses, decreased the increase in harmful m...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Xueyan Wang Lijun Pan Feiqing Wang Fengxi Long Bing Yang Dongxin Tang Source Type: research
Genetic variants that impact alternative polyadenylation in cancer represent candidate causal risk loci
Cancer Res. 2023 Sep 5. doi: 10.1158/0008-5472.CAN-23-0251. Online ahead of print.ABSTRACTAlternative polyadenylation (APA) is emerging as a major mechanism of post-transcriptional regulation. APA can impact the development and progression of cancer, suggesting that the genetic determinants of APA might play an important role in regulating cancer risk. Here, we depicted a pan-cancer atlas of human APA quantitative trait loci (apaQTLs), containing approximately 0.7 million apaQTLs across 32 cancer types. Systematic multi-omics analyses indicated that cancer apaQTLs could contribute to APA regulation by altering poly(A) moti...
Source: Cell Research - September 5, 2023 Category: Cytology Authors: Bin Li Yimin Cai Can Chen Gaoyuan Li Ming Zhang Zequn Lu Fuwei Zhang Jinyu Huang Linyun Fan Caibo Ning Yanmin Li Wenzhuo Wang Hui Geng Yizhuo Liu Shuoni Chen Hanting Li Shuhui Yang Heng Zhang Wen Tian Zhongchao Zhu Bin Xu Heng Li Haijie Li Meng Jin Xiaoya Source Type: research
Comorbidity Patterns in Patients Newly Diagnosed With Colorectal Cancer: Network-Based Study
CONCLUSIONS: Male-female and urban-rural disparities in the prevalence of single comorbidities and their complex coexistence relationships in new CRC cases were not due to simple coincidence. The results reflect clinical practice in CRC patients and emphasize the importance of measuring comorbidity patterns in terms of individual and coexisting diseases in order to better understand comorbidity patterns.PMID:37669093 | DOI:10.2196/41999
Source: Atherosclerosis - September 5, 2023 Category: Cardiology Authors: Hang Qiu Liya Wang Li Zhou Xiaodong Wang Source Type: research
Association of DNA methylation of vitamin D metabolic pathway related genes with colorectal cancer risk
CONCLUSIONS: This study indicated that the cumulative methylation levels of significant CpG sites in VDR and CYP24A1 and all CpG sites in CYP2R1 were inversely associated with colorectal cancer risk.PMID:37644572 | PMC:PMC10463505 | DOI:10.1186/s13148-023-01555-0
Source: Clinical Colorectal Cancer - August 29, 2023 Category: Cancer & Oncology Authors: Yi-Fan Wang Lei Li Xue-Qing Deng Yu-Jing Fang Cai-Xia Zhang Source Type: research
Performance of different colorectal cancer screening strategies: a long-term passive follow-up population-based screening program in Beijing, China
CONCLUSION: The Beijing CRC screening program can effectively detect early-onset CRC; however, the compliance with colonoscopy still needs to be improved.PMID:37641033 | DOI:10.1186/s12889-023-16564-0
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Xi Zhang Lei Yang Shuo Liu Huichao Li Qingyu Li Haoxin Li Ning Wang Jiafu Ji Source Type: research
Bibliometric analysis of the global scientific production on machine learning applied to different cancer types
Environ Sci Pollut Res Int. 2023 Aug 11. doi: 10.1007/s11356-023-28576-9. Online ahead of print.ABSTRACTCancer disease is one of the main causes of death in the world, with million annual cases in the last decades. The need to find a cure has stimulated the search for efficient treatments and diagnostic procedures. One of the most promising tools that has emerged against cancer in recent years is machine learning (ML), which has raised a huge number of scientific papers published in a relatively short period of time. The present study analyzes global scientific production on ML applied to the most relevant cancer types thr...
Source: Environmental Science and Pollution Research International - August 11, 2023 Category: Environmental Health Authors: Miguel Angel Ruiz-Fresneda Alfonso Gij ón Pablo Morales- Álvarez Source Type: research
