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Total 26 results found since Jan 2013.
Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters.
[time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news
New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion
This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research
10 Ways to Keep Your Heart Healthy
No one ever had fun visiting the cardiologist. Regardless of how good the doc might be, it’s always a little scary thinking about the health of something as fundamental as the heart. But there are ways to take greater control—to ensure that your own heart health is the best it can be—even if you have a family history of cardiovascular disease.
Although 50% of cardiovascular-disease risk is genetic, the other 50% can be modified by how you live your life, according to Dr. Eugenia Gianos, director of Women’s Heart Health at Lenox Hill Hospital in New York City. “This means you can greatly ...
Source: TIME: Health - October 17, 2018 Category: Consumer Health News Authors: Lisa Lombardi and Jamie Ducharme Tags: Uncategorized Baby Boomer Health heart health Source Type: news
The current and potential health benefits of the National Health Service Health Check cardiovascular disease prevention programme in England: A microsimulation study
ConclusionsOur model indicates that the current NHS Health Check programme is contributing to improvements in health and reducing health inequalities. Feasible changes in the organisation of the programme could result in more than a 3-fold increase in health benefits.
Source: PLoS Medicine - March 6, 2018 Category: Internal Medicine Authors: Oliver T. Mytton Source Type: research
Association between Exposure to p,p ′-DDT and Its Metabolite p,p′-DDE with Obesity: Integrated Systematic Review and Meta-Analysis
Conclusions:
We classified p,p′-DDT and p,p′-DDE as “presumed” to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527
Received: 17 May 2016
Revised: 04 May 2017
Accepted: 09 May 2017
Published: 18 September 2017
Please address correspondence to M.A. La Merrill, Dept. of Environmental Toxicology, University of California, Davis, 1 Shields Ave., 4245 Meyer Hall, Davis, CA 95616-5270 USA. Telephone: (530) 754-7254. Email: mlamerrill...
Source: EHP Research - September 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
Being overweight, not just obese, still carries serious health risks
Conclusion
This impressively large global study demonstrates that the prevalence of obesity is increasing worldwide among both children and adults. It supports what has long been thought, that increased body mass index (BMI) contributes to a range of illnesses and is ultimately responsible for a large number of deaths, particularly from cardiovascular disease.
One potential limitation is the use of self-reported BMI or health outcome data in some of the studies, although the majority used a specific independent measurement so this is unlikely to have biased results too much.
It is also always difficult from observational d...
Source: NHS News Feed - June 13, 2017 Category: Consumer Health News Tags: Obesity Source Type: news
Task-based weight management programme delivered in primary care promotes better long-term weight loss among women from lower socioeconomic groups than usual practice
Commentary on: McRobbie H, Hajek P, Peerbux S, et al.. Tackling obesity in areas of high social deprivation: clinical effectiveness and cost-effectiveness of a task-based weight management group programme—a randomised controlled trial and economic evaluation. Health Technol Assess 2016;20:1–150. Implications for practice and research The study is important in demonstrating that a task-based weight management programme can potentially be effective in reducing obesity among lower socioeconomic groups. The role of nurses in delivering such weight loss interventions should be evaluated. Context Obesity is recognise...
Source: Evidence-Based Nursing - March 22, 2017 Category: Nursing Authors: Bambra, C. Tags: Health promotion and public health Source Type: research
Role of Endoscopic Gastroplasty Techniques in the Management of Obesity.
Authors: Jung Y
Abstract
Health and wellness represent a major global concern. Trends such as a lack of exercise and excessive consumption of calories are major causes of the rapid increase in obesity worldwide. Obesity should be controlled because it can result in other illnesses, such as diabetes, high blood pressure, high cholesterol, coronary artery disease, stroke, breathing disorders, or cancer. However, many people have difficulty in managing obesity through exercise, dietary control, behavioral modifications, and drug therapy. Bariatric surgery is not commonly used due to a variety of complications, even th...
Source: Clinical Endoscopy - February 5, 2017 Category: Gastroenterology Tags: Clin Endosc Source Type: research
Want to Lose Weight? Add This One Thing to Your Diet
What are the best ways to lose weight? originally appeared on Quora - the knowledge sharing network where compelling questions are answered by people with unique insights.
Answer by Keck Medicine of USC, 500+ internationally renowned doctors at a leading academic medical center, on Quora:
Learn the secret to losing weight - and improve your overall health at the same time.
Fiber. It's not a sexy solution, but it's one that works wonders for maintaining a healthy weight. Beans, vegetables, fruit and grains all contain fiber, which helps keep your digestive tract clean, healthy and at peak function.
But, did you know that...
Source: Healthy Living - The Huffington Post - December 28, 2016 Category: Consumer Health News Source Type: news
Association between weight change and mortality in community living older people followed for up to 14 years. The Hordaland Health Study (HUSK)
ConclusionEven a minor weight loss of ≥5% or>3 kg were significantly associated with increased risk of mortality. Thus, weight should be routinely measured in older adults.
Source: The Journal of Nutrition, Health and Aging - December 16, 2016 Category: Nutrition Source Type: research
Leading Health Mistakes Women Make In Their 30s
Credit
For many women, turning 30 marks the real beginning of adulthood. You're established in a career, and maybe in a relationship. You might be thinking about starting a family. You feel pretty good about yourself, and all the health indiscretions of your 20s (remember those all-night parties and how you still managed to make it into work the next day?) haven't taken much of a health toll.
But let's face it, ages 30 to 39 are prime time. All in all, the 30s are a very positive time for health, but it's also the time you have to start developing excellent habits as an investment in the future, says Dr. Debra DeJoseph,...
Source: Healthy Living - The Huffington Post - August 17, 2016 Category: Consumer Health News Source Type: news
Ask JJ: Type 2 Diabetes
Dear JJ: My doctor just diagnosed me with pre-diabetes. Type 2 diabetes runs in my family, but I will not accept it as my fate. You've written about sugar's detrimental impact, so how can I get this under control so it doesn't blow up into full-blown diabetes?
Diabetes doesn't happen overnight or linearly, but when your metabolic machinery breaks, serious havoc ensues. The massive repercussions can become deadly.
Every time you eat, you raise blood sugar, which triggers your pancreas to release a hormone called insulin. Every food raises blood sugar, but high-sugar impact foods do it big time.
Your pancreas "secretes s...
Source: Healthy Living - The Huffington Post - June 16, 2016 Category: Consumer Health News Source Type: news
Study Reveals That Eating 'In Moderation' Is A Fool's Errand
"Everything in moderation" is a common piece of healthy eating advice from slim and sexy celebs, dietitians and other lifestyle gurus. It's a call that's thousands of years old: The ancient Greek poet Hesiod wrote the phrase “moderation is best in all things” in his poem Work and Days, written around 700 BCE, and other philosophers and writers have echoed the maxim ever since.
But just because it’s a saying that has persisted throughout history doesn’t mean it’s right, helpful or useful.
While it sounds like wise advice for anyone who wants a low-key approach to healthy eating...
Source: Science - The Huffington Post - June 9, 2016 Category: Science Source Type: news
Obesity in the U.S. and Europe on the Rise: A Comparison
Levels of obesity in adults and children are rising worldwide. The World Health Organization calls the rising level "an epidemic" citing sugary drinks and processed foods as the main culprits, along with an urban sedentary lifestyle.
A study published in The Lancet named "Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013" stated obesity issues "were estimated to have caused 3.4 million deaths globally, most of which were from cardiovascular causes. Research indicates that if left unaddressed, the ri...
Source: Healthy Living - The Huffington Post - May 5, 2016 Category: Consumer Health News Source Type: news
