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Histopathological and immunohistochemical study of periodontal changes in chronic smokers
Rom J Morphol Embryol. 2021 Jan-Mar;62(1):209-217. doi: 10.47162/RJME.62.1.20.ABSTRACTPeriodontal disease is a chronic inflammatory, multifactorial condition, that, in the absence of an early and adequate treatment, may lead to a progressive damaging of the alveolar tissues that support the teeth (periodontal ligament, cement and alveolar bone) followed by teeth mobility and, subsequently, their loss. Periodontal disease is one of the most common inflammatory disease affecting adult individuals all over the world, being considered a real worldwide pandemic. This disease may influence the progression of certain systemic dis...
Source: Romanian Journal of Morphology and Embryology - October 5, 2021 Category: General Medicine Authors: Gabriel Valeriu Popa Adrian Costache Oana Badea Melania Olimpia Cojocaru George Mitroi Adela Cristina Laz ăr Daniel Alin Olimid Lauren ţiu Mogoantă Source Type: research

Association between fasting blood glucose levels and stroke events: a large-scale community-based cohort study from China
Conclusions Higher FBG level was independently associated with an increased risk of stroke in Chinese adults, especially significant in women.
Source: BMJ Open - August 18, 2021 Category: General Medicine Authors: Zhang, Y., Gu, S., Wang, C., Liu, D., Zhang, Q., Yang, M., Zhou, Z., Zuo, H. Tags: Open access, Public health Source Type: research

Effective chemotherapy and targeted therapy supplemented with stereotactic radiotherapy of a patient with metastatic colon cancer following renal transplantation: a case report
ConclusionsSince information is scarce regarding oncological treatment of patients following organ transplantation, data about their oncological treatment is essential. To our knowledge, this is the first case report to describe the successful chemotherapy and targeted therapy supplemented with stereotactic radiotherapy of a posttransplant patient with metastatic colorectal cancer.
Source: Journal of Medical Case Reports - March 20, 2021 Category: General Medicine Source Type: research

Health Behaviors in Rural Appalachia.
CONCLUSIONS: This community-based sample demonstrated elevated behavioral risk factors that likely contribute to some of the nation's highest rates of premature mortality. Despite suboptimal dietary intake and physical activity, results indicate some potential leverage points between the generations that may be used to improve health. For example, the older generation could benefit from engaging with their younger relatives in physical activities while advocating for a better-rounded diet. Given traditions of intergenerational connectedness, mutual aid, and self-reliance, transmission of healthier behaviors across the gene...
Source: Southern Medical Journal - August 5, 2019 Category: General Medicine Tags: South Med J Source Type: research

Cardiovascular disease after childhood acute lymphoblastic leukaemia: a cohort study.
CONCLUSIONS: Despite attempts to reduce cardiotoxicity in childhood cancer treatment, CVD risks in ALL survivors treated more recently do not seem to have declined. PMID: 30852834 [PubMed - in process]
Source: Swiss Medical Weekly - February 24, 2019 Category: General Medicine Authors: Hau EM, Caccia JN, Kasteler R, Spycher B, Suter T, Ammann RA, von der Weid NX, Kuehni CE Tags: Swiss Med Wkly Source Type: research

Obesity and inflammation: the linking mechanism and the complications.
Authors: Ellulu MS, Patimah I, Khaza'ai H, Rahmat A, Abed Y Abstract Obesity is the accumulation of abnormal or excessive fat that may interfere with the maintenance of an optimal state of health. The excess of macronutrients in the adipose tissues stimulates them to release inflammatory mediators such as tumor necrosis factor α and interleukin 6, and reduces production of adiponectin, predisposing to a pro-inflammatory state and oxidative stress. The increased level of interleukin 6 stimulates the liver to synthesize and secrete C-reactive protein. As a risk factor, inflammation is an imbedded mechanism of develo...
Source: Archives of Medical Science - July 20, 2017 Category: General Medicine Tags: Arch Med Sci Source Type: research

Pneumonia in the Noninstitutionalized Older Population.
CONCLUSION: Pneumonia plays an important role in the medical care of non-institutionalized older people. With the aid of the predictors identified in this study, primary care physicians can identify patients at risk, smokers can gain additional motivation to quit, treatment compliance can be increased, and patients may become more willing to be vaccinated as recommended in the current guidelines. PMID: 27697144 [PubMed - in process]
Source: Deutsches Arzteblatt International - October 5, 2016 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research

Association between resting heart rate and coronary artery disease, stroke, sudden death and noncardiovascular diseases: a meta-analysis.
Authors: Zhang D, Wang W, Li F Abstract BACKGROUND: Resting heart rate is linked to risk of coronary artery disease, stroke, sudden death and noncardiovascular diseases. We conducted a meta-analysis to assess these associations in general populations and in populations of patients with hypertension or diabetes mellitus. METHODS: We searched PubMed, Embase and MEDLINE from inception to Mar. 5, 2016. We used a random-effects model to combine study-specific relative risks (RRs). We used restricted cubic splines to assess the dose-response relation. RESULTS: We included 45 nonrandomized prospective cohort studi...
Source: Canadian Medical Association Journal - August 24, 2016 Category: Journals (General) Tags: CMAJ Source Type: research

Acute Ischemic Stroke on Cancer Patients, a Distinct Etiology? A Case-Control Study.
CONCLUSION: In clinical grounds, hypercoagulopathy as stroke etiology should prompt the physician to screen the patient for occult cancer. PMID: 26667865 [PubMed - in process]
Source: Acta Medica Portuguesa - December 18, 2015 Category: Journals (General) Tags: Acta Med Port Source Type: research

Assessment of primary care facilities for cardiovascular disease preparedness in Madhya Pradesh, India
Conclusions: Increasing burden of NCDs like hypertension and diabetes mellitus necessitates public health response through health systems. Therefore health system preparedness in form of trained human resources, functional laboratories and well stocked pharmacies are essential in primary care facilities.
Source: BMC Health Services Research - September 23, 2015 Category: Journals (General) Authors: Abhijit PakhareSanjeev KumarSwati GoyalRajnish Joshi Source Type: research

The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study)
Introduction Blue light information plays an important role in synchronising internal biological rhythm within the external environment. Circadian misalignment is associated with the increased risk of sleep disturbance, obesity, diabetes mellitus, depression, ischaemic heart disease, stroke and cancer. Meanwhile, blue light causes photochemical damage to the retina, and may be associated with age-related macular degeneration (AMD). At present, clear intraocular lenses (IOLs) and blue-blocking IOLs are both widely used for cataract surgery; there is currently a lack of randomised controlled trials to determine whether clear...
Source: BMJ Open - May 12, 2015 Category: Journals (General) Authors: Nishi, T., Saeki, K., Obayashi, K., Miyata, K., Tone, N., Tsujinaka, H., Yamashita, M., Masuda, N., Mizusawa, Y., Okamoto, M., Hasegawa, T., Maruoka, S., Ueda, T., Kojima, M., Matsuura, T., Kurumatani, N., Ogata, N. Tags: Open access, Epidemiology, Ophthalmology Protocol Source Type: research

Information and Communication Technology–Enabled Person-Centered Care for the “Big Five” Chronic Conditions: Scoping Review
Conclusions: This scoping review outlined ICT-enabled PCC in chronic disease management. Persons with a chronic disease could benefit from an ICT-enabled PCC approach, but ICT-PCC also yields organizational paybacks. It could lead to an increase in health care usage, as reported in some studies. Few interventions could be regarded as “fully” addressing PCC. This review will be especially helpful to those deciding on areas where further development of research or implementation of ICT-enabled PCC may be warranted.
Source: Journal of Medical Internet Research - March 27, 2015 Category: Journals (General) Authors: Sabine E WildevuurLianne WL Simonse Source Type: research

Duplex sonography for detection of deep vein thrombosis of upper extremities: a 13-year experience.
CONCLUSIONS. Upper-extremity deep vein thrombosis is uncommon among symptomatic Chinese population. The most common sign is swelling and the major risk factor for upper-extremity deep vein thrombosis identified in this study is malignancy. PMID: 25722467 [PubMed - as supplied by publisher]
Source: Hong Kong Med J - February 27, 2015 Category: Journals (General) Authors: Chung AS, Luk WH, Lo AX, Lo CF Tags: Hong Kong Med J Source Type: research

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