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Vaccination: Influenza Vaccine

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Total 1458 results found since Jan 2013.

Johnson & Johnson Expands Phase 2a Clinical Trial of COVID-19 Vaccine Candidate to Include Adolescents
New Brunswick, NJ (April 2, 2021) – Johnson & Johnson (the Company) has begun vaccinating adolescent participants in the ongoing Phase 2a clinical trial for its COVID-19 vaccine candidate, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson. “The COVID-19 pandemic has had a profound impact on adolescents, not just with the complications of the disease, but with their education, mental health, and wellbeing,” said Paul Stoffels, M.D., Vice Chairman of the Executive Committee and Chief Scientific Officer at Johnson & Johnson. “It is vital that we develop vaccines for everyone, everywher...
Source: Johnson and Johnson - April 2, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Let ’s Not Be Fatalistic About Omicron. We Know How to Fight It
The new, heavily mutated variant of SARS-CoV-2, Omicron first detected by scientists in South Africa, has put the public health community worldwide on high alert and the public on edge. Since then, evidence has mounted that the variant is highly transmissible. It is far more transmissible than, and is coming to predominate over, its immediately preceding variant, Delta. Omicron’s doubling time—how long it takes for the number of coronavirus cases to double—is just two to three days. The first indications from South Africa are that infection with the Omicron variant may have milder consequences than infect...
Source: TIME: Health - December 15, 2021 Category: Consumer Health News Authors: Gavin Yamey, William Hanage and Tom Moultrie Tags: Uncategorized COVID-19 Source Type: news

The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses
In this study, we explore the suitability of the rapid accelerated fibrosarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (Raf/MEK/ERK) pathway as a druggable target in the treatment of SARS-CoV-2 infections. We find that SARS-CoV-2 transiently activates Raf/MEK/ERK signaling in the very early infection phase and that ERK1/2 knockdown limits virus replication in cell culture models. We demonstrate that ATR-002, a specific inhibitor of the upstream MEK1/2 kinases which is currently evaluated in clinical trials as an anti-influenza drug, displays strong anti-SARS-CoV-2 activity in cell lines as w...
Source: Cellular and Molecular Life Sciences : CMLS - January 11, 2022 Category: Cytology Authors: Andr é Schreiber Dorothee Viemann Jennifer Sch öning Sebastian Schloer Angeles Mecate Zambrano Linda Brunotte Aileen Faist Michael Sch öfbänker Eike Hrincius Helen Hoffmann Markus Hoffmann Stefan P öhlmann Ursula Rescher Oliver Planz Stephan Ludwig Source Type: research

The (sort of, partial) Father mRNA Vaccines Who Now Spreads Vaccine Misinformation (Part 2)
By DAVID WARMFLASH, MD This is part 2 of David Warmlash’s takedown of Robert W. Malone’s appearance (transcript) on the Rogan podcast. Part 1 is here Menstruation and Fertility Much more than the line about reproductive damage in the Wisconsin News clip that we used to open the story, Malone used the Rogan interview to dive more deeply into the topic, starting with:  …there’s a huge number of dysmenorrhea and menometrorrhagia… By that, he meant excessive menstrual cramping and very heavy, often irregular, bleeding, which he followed up with: …they DENY it… Judging by other parts ...
Source: The Health Care Blog - March 18, 2022 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy antivaxxer COVID-19 vaccine David Warmflash Joe Rogan Robert Malone Source Type: blogs

Epidemiologic characteristics of SARS-CoV-2 in Wuhan, other regions of China, and globally based on data gathered from January 2020 to February 2021
This observation study examines coronavirus disease 2019 (COVID-19) data from outbreak and other sites in China and worldwide in order to examine the epidemiological pattern of COVID-19 before the acquisition of immunity through widespread vaccination and infection. COVID-19–related morbidity and mortality data for January 2020 to February 2021 were obtained from the Chinese Center for Disease Control and Prevention, Hubei Provincial Center for Disease Control and Prevention, and the World Health Organization. The number of cases was logarithmically transformed for comparison of the rate of increase or decrease with time...
Source: Medicine - August 12, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

TWiV 582: This little virus went to market
TWiV provides updates on the new coronavirus causing respiratory disease in China, the current influenza season, and the epidemic of African swine fever, including determination of the three-dimensional structure of the virus particle. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Download TWiV 582 (71 MB .mp3, 118 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV 2020 NJ ready to remove religious vaccine exemptions (Patch) New virus causing pneumonia in China (NY Times) New China virus is coronavirus (NY ...
Source: This Week in Virology - MP3 Edition - January 12, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Taiwan Has Been Shut Out of Global Health Discussions. Its Participation Could Have Saved Lives
Eight hundred and fifty thousand of Taiwan’s 23 million citizens reside in mainland China. Four hundred thousand work there. At its narrowest point, the Taiwan Strait between the island and the mainland is just 130 km. So, by all accounts, Taiwan should be in the midst a major coronavirus outbreak. Instead, as of March 18, it had seen just 100 cases compared to the more than 80,000 in China and the tens of thousands in several countries in Europe. This has not happened by chance. Learning from the experiences of SARS in 2003, Taiwan was ready when the outbreak in Wuhan occurred. After the first notifications at the e...
Source: TIME: Health - March 18, 2020 Category: Consumer Health News Tags: Uncategorized COVID-19 Source Type: news

The mechanistic target of rapamycin (mTOR): Novel Considerations as an Antiviral Treatment and Possibilities for COVID-19.
Abstract As a rapidly developing etiology of a global disease, the -coronavirus family virion, SARS-CoV-2, has quickly evolved as a pandemic leading to coronavirus disease 2019 (COVID-19) and has been declared by the World Health Organization as a Public Health Emergency of International Concern. To date, no definitive treatment or vaccine application exists for COVID-19. Although new investigations seek to repurpose existing antiviral treatments for COVID-19, innovative treatment strategies not normally considered to have antiviral capabilities may be critical as well to address this global concern. One such a...
Source: Current Neurovascular Research - April 24, 2020 Category: Neurology Authors: Maiese K Tags: Curr Neurovasc Res Source Type: research

Social Distancing against COVID-19: Implication for the Control of Influenza.
Authors: Noh JY, Seong H, Yoon JG, Song JY, Cheong HJ, Kim WJ Abstract Social distancing has been adopted as one of basic protective measures against coronavirus disease 2019 (COVID-19). During 2019-2020 season, influenza epidemic period was exceptionally short and epidemic peak was low in comparison with previous seasons in Korea. Influenza epidemic pattern was bimodal in 2016-2017 and 2018-2019 seasons, however, influenza viruses have rarely been circulating in spring, 2020 in Korea. Although multiple factors could affect the size of influenza epidemic, extensive application of nonpharmaceutical interventions inc...
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Passive immunization: Paradoxical and traditional method for new pandemic challenge COVID-19.
Abstract World has been suffering from pandemic caused by mysterious Coronavirus. The novel member of Coronaviridae causing COVID-19 disease is named as SARS-Cov-2. Its first case was reported in China by the end of 2019, but its exponential spread has wrapped entire globe, suspended and is penalizing mankind. A retrospective meta-analysis study showed that outbreaks of Middle East Respiratory Syndrome (MERS) and SARS-Cov-1 (Coronaviridae), influenza infection H1N1 and West-African Ebola caused lower mortality than this new pandemic COVID-19. Virus has appeared as a new human pathogen so to counter COVID-19 no spe...
Source: Acta Microbiologica et Immunologica Hungarica - July 1, 2020 Category: Microbiology Authors: Iftikhar A, Jabeen F, Manzoor M, Younis T, Shaheen M Tags: Acta Microbiol Immunol Hung Source Type: research

SARS-CoV-2 will constantly sweep its tracks: a vaccine containing CpG motifs in ‘lasso’ for the multi-faced virus
AbstractDuring the current COVID-19 pandemic, the global ratio between the dead and the survivors is approximately 1 to 10, which has put humanity on high alert and provided strong motivation for the intensive search for vaccines and drugs. It is already clear that if we follow the most likely scenario, which is similar to that used to create seasonal influenza vaccines, then we will need to develop improved vaccine formulas every year to control the spread of the new, highly mutable coronavirus SARS-CoV-2. In this article, using well-known RNA viruses (HIV, influenza viruses, HCV) as examples, we consider the main success...
Source: Inflammation Research - July 11, 2020 Category: Research Source Type: research

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2020-21 Influenza Season.
This report updates the 2019-20 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal influenza vaccines in the United States (MMWR Recomm Rep 2019;68[No. RR-3]). Routine annual influenza vaccination is recommended for all persons aged ≥6 months who do not have contraindications. For each recipient, a licensed and age-appropriate vaccine should be used. Inactivated influenza vaccines (IIVs), recombinant influenza vaccine (RIV4), and live attenuated influenza vaccine (LAIV4) are expected to be available. Most influenza vaccines available for the 2020-21 season will be qua...
Source: MMWR Recomm Rep - August 20, 2020 Category: Epidemiology Authors: Grohskopf LA, Alyanak E, Broder KR, Blanton LH, Fry AM, Jernigan DB, Atmar RL Tags: MMWR Recomm Rep Source Type: research

How Convalescent Plasma Could Help Fight COVID-19
The last time most of us gave any thought to antibodies was probably in high school biology, but we’re getting a crash refresher course thanks to COVID-19. They are, after all, the key to our best defenses against SARS-CoV-2, the virus that’s caused the global pandemic. People who have been infected likely rely on antibodies to recover, and antibodies are what vaccines are designed to produce. Or at least that’s what infectious-disease and public-health experts assume for now. Because SARS-CoV-2 is such a new virus, even the world’s best authorities aren’t yet sure what it will take to build p...
Source: TIME: Health - August 24, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Convalescent plasma treatment for COVID-19: tempering expectations with the influenza experience.
This article is protected by copyright. All rights reserved. PMID: 32886952 [PubMed - as supplied by publisher]
Source: European Journal of Immunology - September 3, 2020 Category: Allergy & Immunology Authors: Subbarao K, Mordant F, Rudraraju R Tags: Eur J Immunol Source Type: research

How Flu Shots Can Help in the Fight Against Covid-19
Experts worry that the two diseases could overwhelm the health care system and create a new shortage of hospital beds and personal protective equipment.
Source: NYT Health - September 15, 2020 Category: Consumer Health News Authors: Jane E. Brody Tags: Influenza Coronavirus (2019-nCoV) Vaccination and Immunization Coronavirus Risks and Safety Concerns Medicine and Health Masks Respiratory Diseases Source Type: news