HSV-1 Amplicon Vectors as Genetic Vaccines
HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D’Antuono et al. Vaccine 28: 7363–7372, 2010; Laimbacher et al. Mol Ther 20: 1810–1820, 2012), indicating that HSV-1 amplicon vectors are attractive tools for the development of complex and safe genetic vaccines. This chapter describes the use of HSV-1 amplicon vectors that encode individual or multiple viral...
Source: Springer protocols feed by Infectious Diseases - April 3, 2014 Category: Infectious Diseases Source Type: news
Childhood virus may increase type 1 diabetes risk
The most common cause of severe diarrhea in children, the rotavirus infection, has been shown to accelerate the development of type 1 diabetes in mice. The research found that it may be the "bystander effect" that causes the rotavirus infection to accelerate the onset of type 1 diabetes. The "bystander effect" suggests that the virus provokes a strong activation of the immune system, which then spills over, allowing the immune system to attack not only the viral intruder but some of the body's own cells, in this case the insulin-producing cells in the pancreas. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 31, 2014 Category: Science Source Type: news
Cameroon: Rotavirus Diarrhoea - Cameroon's First Lady Leads Vaccination Crew
[Cameroon Tribune]Excitement gripped thousands of women, children and health officials on March 28, 2014, at the Yaounde Multipurpose Sport Complex, when the First Lady of Cameroon, UNESCO Goodwill Ambassador for Education and Social Inclusion, Mrs Chantal Biya, made an exultant entrance into the building at exactly midday to officially launch and introduce the rotavirus vaccine into the National Immunization Programme of the country. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 31, 2014 Category: African Health Source Type: news
Cameroon: Medics Battle Rotavirus
[VOA]Yaounde -In the past 12 months, thousands of children in Cameroon have died of severe diarrhea caused by rotavirus, with thousands more said to be hospitalized. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 29, 2014 Category: African Health Source Type: news
Cameroon: Cameroon to Protect Its Children Against Leading Cause of Severe Diarrhoea
[GAVI]Yaoundé -Life-saving rotavirus vaccines to be offered as part of country's routine immunisation programme (joint press release UNICEF, WHO, GAVI Alliance) (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 28, 2014 Category: African Health Source Type: news
Africa: Gavi-Supported Pneumo and Rota Studies Published
[GAVI]Reviews highlight effectiveness of pneumococcal vaccine dosing schedule and importance of rotavirus surveillance (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 28, 2014 Category: African Health Source Type: news
How rotavirus infection accelerates autoimmune diabetes in a mouse model
A combination of genetic predisposition and environmental factors is believed to cause autoimmune (type 1) diabetes. A new study gets at the mechanisms by which rotavirus infection contributes to autoimmune diabetes in a mouse model of the disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 28, 2014 Category: Science Source Type: news
How rotavirus infection accelerates autoimmune diabetes in a mouse model
(PLOS) A combination of genetic predisposition and environmental factors is believed to cause autoimmune (type 1) diabetes. A study published on March 27 in PLOS Pathogens gets at the mechanisms by which rotavirus infection contributes to autoimmune diabetes in a mouse model of the disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 27, 2014 Category: Infectious Diseases Source Type: news
Childhood virus may increase type 1 diabetes risk
(University of Melbourne) The most common cause of severe diarrhea in children, the rotavirus infection, has been shown to accelerate the development of type 1 diabetes in mice, according to new University of Melbourne research. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 27, 2014 Category: Infectious Diseases Source Type: news
South Africa: Guidelines - Expanded Program On Immunisation Vaccine Guidelines, Manual
[Health-e]Updated in 2010, these guidelines include South Africa's introduction of the pneumococcal conjugate and rotavirus vaccines. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 7, 2014 Category: African Health Source Type: news
CDC Report Says Accidental Injection Of Oral Rotavirus Vaccine More Frequent In GSK Than Merck Products
The Centers for Disease Control and Prevention have released a recent report about mistakes in administrating oral rotavirus vaccine in the U.S. Injecting oral rotavirus vaccine renders it ineffective. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - February 13, 2014 Category: Pharmaceuticals Source Type: news
Notes from the Field: Rotavirus Vaccine Administration Errors — United States, 2006–2013
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 31, 2014 Category: American Health Source Type: news
CDC Finds Eye Splashes, Misdelivery of Rotavirus VaccineCDC Finds Eye Splashes, Misdelivery of Rotavirus Vaccine
CDC researchers have reported several cases of misdelivered oral, live rotavirus vaccine by injection and eye splashes during administration, recommend prevention with proper education and training. Medscape Medical News (Source: Medscape Nurses Headlines)
Source: Medscape Nurses Headlines - January 31, 2014 Category: Nursing Tags: Pediatrics News Source Type: news
Newer Rotavirus Vaccines Linked to Small but Definite Increase in Intussusception Risk (FREE)
By Joe Elia
Two studies find small but significantly increased risks for intussusception in U.S. infants receiving current rotavirus vaccines. Editorialists in the New England Journal of Medicine emphasize that the benefits trump the risks — … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 15, 2014 Category: Primary Care Source Type: news
Rotavirus Vaccines Carry Low Risk for IntussusceptionRotavirus Vaccines Carry Low Risk for Intussusception
Data from 2 US surveillance studies suggest that the risks for intestinal obstruction from currently available rotavirus vaccines are far outweighed by the benefits. Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 14, 2014 Category: Gastroenterology Tags: Pediatrics News Source Type: news
