Rosemary Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Arming up against Omicron subvariants
Cell Host Microbe. 2024 Feb 14;32(2):147-148. doi: 10.1016/j.chom.2024.01.010.ABSTRACTThe rapid evolution of COVID-19 Omicron variants is driven by evasion of neutralizing antibodies. Breakthrough infections are common, even in highly vaccinated populations, making it vital to understand immune cross-protective repertoires to variants. Two studies in this issue show that the primed T cell repertoire comprises strong cross-recognition of current variants.PMID:38359794 | DOI:10.1016/j.chom.2024.01.010 (Source: Cell Host and Microbe)
Source: Cell Host and Microbe - February 15, 2024 Category: Microbiology Authors: Daniel M Altmann Rosemary J Boyton Source Type: research

FDA-approved disulfiram as a novel treatment for aggressive leukemia
This study assessed the biological effects of disulfiram on leukemia cells and evaluated its potential as a treatment strategy. We found that disulfiram inhibits the viability of a diverse panel of acute lymphoblastic and myeloid leukemia cell lines (n = 16) and patient-derived xenograft cells from patients with poor outcome and treatment-resistant disease (n = 15). The drug induced oxidative stress and apoptosis in leukemia cells within hours of treatment and was able to potentiate the effects of daunorubicin, etoposide, topotecan, cytarabine, and mitoxantrone chemotherapy. Upon combining disulfiram with auranofin, a drug...
Source: Molecular Medicine - February 13, 2024 Category: Molecular Biology Authors: Mawar Karsa Lin Xiao Emma Ronca Angelika Bongers Dayna Spurling Ayu Karsa Sandra Cantilena Anna Mariana Tim W Failes Greg M Arndt Laurence C Cheung Rishi S Kotecha Rosemary Sutton Richard B Lock Owen Williams Jasper de Boer Michelle Haber Murray D Norris Source Type: research

Exploring Interprofessional Collaboration in Teaching Between Nursing and Physical Therapy
CONCLUSION: Interprofessional collaboration in teaching resulted in high levels of satisfaction and self-confidence and provided an opportunity to work toward an aspect of core competency for interprofessional collaborative practice. [J Nurs Educ. 2024;63(X):XXX-XXX.].PMID:38346352 | DOI:10.3928/01484834-20240130-03 (Source: The Journal of Nursing Education)
Source: The Journal of Nursing Education - February 12, 2024 Category: Nursing Authors: Denise Romano Rosemary Collier Thomas Komor Lori-Marie Sprague Source Type: research