Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan
Jpn J Infect Dis. 2021 Dec 28. doi: 10.7883/yoken.JJID.2021.751. Online ahead of print.ABSTRACTCirculation of avian influenza A viruses in poultry is a public health concern because these viruses may cause severe disease in humans and have the potential to become more transmissible among humans. Monitoring the susceptibility of these viruses to antivirals is important for influenza pandemic preparedness. However, information about their antiviral susceptibility is limited. Here, we determined the susceptibilities of avian influenza A(H5N1), A(H5N2), A(H5N8), A(H7N7), A(H7N9), A(H9N1), and A(H9N2) viruses isolated in Japan ...
Source: Japanese Journal of Infectious Diseases - January 4, 2022 Category: Infectious Diseases Authors: Emi Takashita Hiroko Morita Shiho Nagata Masayuki Shirakura Seiichiro Fujisaki Hideka Miura Ikuyo Takayama Tomoko Arita Yasushi Suzuki Masaoki Yamaoka Taichiro Tanikawa Ryota Tsunekuni Junki Mine Saki Sakuma Yuko Uchida Akihiro Shibata Mari Iwanaka Noriko Source Type: research
[PERSPECTIVES] Antivirals Targeting the Neuraminidase
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that competitively bind to the NA active site and potently inhibit enzyme activity have been synthesized and tested. Four NA inhibitors are now licensed in various parts of the world (zanamivir, oseltamivir, peramivir, and laninamivir) to treat influenza A and B infections. NA changes, naturally occurring or acquired under selective pressure, have been shown to reduce drug binding, thereby affecting the effectiveness of NA inhibitors. Drug resist...
Source: Cold Spring Harbor perspectives in medicine - January 4, 2022 Category: Research Authors: Gubareva, L., Mohan, T. Tags: Influenza: The Cutting Edge PERSPECTIVES Source Type: research
Antiviral Treatments for Influenza
Semin Respir Crit Care Med. 2021 Dec;42(6):859-872. doi: 10.1055/s-0041-1733830. Epub 2021 Dec 16.ABSTRACTInfluenza is an acute respiratory illness caused by the influenza A, B, and C viruses. It can occur in local outbreaks or seasonal epidemics, with possibility to spread worldwide in a pandemic when a novel strain with significant antigenic differences emerges. During the past years, several new drugs have become available, with different accessibility related to specific countries' approval. We have conducted a review of literature, analyzing the most recent data on efficacy and safety of drugs currently available to t...
Source: Respiratory Care - December 17, 2021 Category: Respiratory Medicine Authors: Emanuele Palomba Valeria Castelli Giulia Renisi Alessandra Bandera Andrea Lombardi Andrea Gori Source Type: research
Antiviral Treatments for Influenza
Semin Respir Crit Care Med. 2021 Dec;42(6):859-872. doi: 10.1055/s-0041-1733830. Epub 2021 Dec 16.ABSTRACTInfluenza is an acute respiratory illness caused by the influenza A, B, and C viruses. It can occur in local outbreaks or seasonal epidemics, with possibility to spread worldwide in a pandemic when a novel strain with significant antigenic differences emerges. During the past years, several new drugs have become available, with different accessibility related to specific countries' approval. We have conducted a review of literature, analyzing the most recent data on efficacy and safety of drugs currently available to t...
Source: Respiratory Care - December 17, 2021 Category: Respiratory Medicine Authors: Emanuele Palomba Valeria Castelli Giulia Renisi Alessandra Bandera Andrea Lombardi Andrea Gori Source Type: research
