European CHMP recommends approval of zanamivir solution for infusion (Dectova) for the treatment of complicated and potentially life-threatening influenza
This opinion summary advises that it will be available as a 10 mg/ml solution for infusion for the treatment of complicated and potentially life-threatening influenza A or B virus infection in patients aged ≥6 months when other anti-virals, including inhaled zanamivir, are not suitable for the patient. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 14, 2019 Category: Consumer Health News Source Type: news
EMA Panel Backs Zanamivir IV for Complicated, Severe Influenza EMA Panel Backs Zanamivir IV for Complicated, Severe Influenza
The EMA ' s Committee for Medicinal Products for Human Use recommended marketing authorization under exceptional circumstances for zanamivir for complicated and potentially life-threatening influenza.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 1, 2019 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
Personal Health: Need a Flu Shot? Get It Now
Immunity tends to wane by 20 percent a month, leaving those who got their shot in August or September with less than desirable protection by the time they ’ re exposed. (Source: NYT Health)
Source: NYT Health - November 5, 2018 Category: Consumer Health News Authors: JANE E. BRODY Tags: Influenza Vaccination and Immunization Tamiflu (Drug) Relenza (Drug) Viruses Epidemics Source Type: news
The FDA Approved a New Flu Treatment, Just In Time for Flu Season
The Food and Drug Administration (FDA) has approved a new antiviral influenza treatment. The agency on Wednesday approved Genentech’s drug Xofluza, which can be taken via a single oral dose to help patients recover more quickly from the flu. It’s the “first new antiviral flu treatment with a novel mechanism of action approved by the FDA in nearly 20 years,” FDA Commissioner Dr. Scott Gottlieb said in a statement. The main factor differentiating Xofluza from other antiviral flu treatments on the market, such as Tamiflu and Relenza, is the way it’s taken. Xofluza is the only antiviral that can b...
Source: TIME: Health - October 24, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Drugs healthytime onetime Source Type: news
At Least 30 Children Have Died From This Season ’s Flu. Some of Them Were Perfectly Healthy
Thirty children have died from confirmed influenza-related causes so far this flu season, according to the Centers for Disease Control and Prevention’s (CDC’s) most recent weekly report, released last Friday. The total includes deaths between Oct. 16 and Jan. 13. CDC Director Brenda Fitzgerald has described the 2017-2018 flu season as “very active,” and has said that much of the country is experiencing “widespread and intense flu activity.” During a Jan. 12 press update, Fitzgerald said that influenza A, H3N2, has been the most common strain of flu virus reported this year. “These ...
Source: TIME: Health - January 22, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized healthytime onetime public health Source Type: news
In the Flu Battle, Hydration and Elevation May Be Your Best Weapons
Bring on the soup: Fluids will help diminish your headache and bolster your immune response. (Source: NYT Health)
Source: NYT Health - January 12, 2018 Category: Consumer Health News Authors: KATE MURPHY Tags: Influenza Tamiflu (Drug) Relenza (Drug) Interferon (Protein) Viruses Fever Vaccination and Immunization Respiratory System Source Type: news
Recurrent infection progressively disables host protection against intestinal inflammation
Intestinal inflammation is the central pathological feature of colitis and the inflammatory bowel diseases. These syndromes arise from unidentified environmental factors. We found that recurrent nonlethal gastric infections of Gram-negative Salmonella enterica Typhimurium (ST), a major source of human food poisoning, caused inflammation of murine intestinal tissue, predominantly the colon, which persisted after pathogen clearance and irreversibly escalated in severity with repeated infections. ST progressively disabled a host mechanism of protection by inducing endogenous neuraminidase activity, which accelerated the molec...
Source: ScienceNOW - December 21, 2017 Category: Science Authors: Yang, W. H., Heithoff, D. M., Aziz, P. V., Sperandio, M., Nizet, V., Mahan, M. J., Marth, J. D. Tags: Medicine, Diseases r-articles Source Type: news
Relenza (Zanamivir) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 25, 2017 Category: Drugs & Pharmacology Source Type: news
Expert panel reviews neuraminidase inhibitors for the prevention and treatment of influenza
(European Centre for Disease Prevention and Control (ECDC)) An ECDC expert opinion concludes that there is clear evidence supporting the use of neuraminidase inhibitors in the treatment and prevention of influenza. Moreover, the current recommendations in European countries on the use of the neuraminidase inhibitors oseltamivir and zanamivir are appropriate and should be applied by prescribing physicians. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 16, 2017 Category: International Medicine & Public Health Source Type: news
Title: zanamivir, RelenzaCategory: MedicationsCreated: 12/5/1999 12:00:00 AMLast Editorial Review: 5/16/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - May 16, 2017 Category: Drugs & Pharmacology Source Type: news
Assessing Fever in Returning Travelers: Part II
Zika continues to be the virus of the day for returning travelers, but there are several other diseases that we need to consider in these patients when they present to us in the emergency department. Chikungunya is epidemic in many of the same countries as Zika and can be even more devastating. And Avian and MERS-CoV is still present in many countries. Unlike patients infected with Zika virus, these patients do require isolation to protect our health care staff from infection. Chikungunya Chikungunya, which means “to walk bent over,” was likely endemic but unrecognized in the United States before the mosquito er...
Source: EPMonthly.com - November 25, 2016 Category: Emergency Medicine Authors: Matt McGahen Tags: Uncategorized Source Type: news
How Effective is Oseltamivir?
Discussion Oseltamivir (Tamiflu®) is an oral neuraminidase inhibitor of influenza viruses types A and B. It first came on the market in Switzerland in 1999 and currently is used around the world along with other neuraminidase inhibitors to treat seasonal and pandemic influenza. Oseltamivir is easily absorbed from the gastrointestinal tract, and circulates to the liver where it is converted to its active metabolite oseltamivir carboxylate (OC). In adults approximately 75% of the oral medication is converted and it then travels to the upper and lower respiratory tracts. Unchanged oseltamivir is eliminated in the urine. ...
Source: PediatricEducation.org - September 5, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Intravenous Zanamivir for Hospitalized Patients With Flu Intravenous Zanamivir for Hospitalized Patients With Flu
An intravenous formulation of a neuraminidase inhibitor is a good option for the treatment of influenza, especially for patients who cannot tolerate oral or inhaled treatments, new research shows.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - August 29, 2016 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
Intravenous Zanamivir for Immunosuppressed Patients With Flu Intravenous Zanamivir for Immunosuppressed Patients With Flu
An intravenous formulation of a neuraminidase inhibitor is a good option for the treatment of influenza, especially for patients who cannot tolerate oral or inhaled treatments, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 29, 2016 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
Scientists Hope Tracking Winter Flu Will Help Close Pandemic Knowledge Gap
ImageContent(562e45c2e4b0aac0b8fd7c69,562e42a91900002e00b94dab,Image,HectorAssetUrl(562e42a91900002e00b94dab,Some(),Some(jpeg)),ViktorCap via Getty Images,) Anyone who goes down with flu in Europe this winter could be asked to enroll in a randomized clinical trial in which they will either be given a drug, which may or may not work, or standard advice to take bed rest and paracetamol. Those who agree could be helping the world prepare for the next potentially deadly disease pandemic as well as helping scientists who are now desperate to plug gaps in knowledge left by previous missed opportunities. Scientists are largely in...
Source: Science - The Huffington Post - October 26, 2015 Category: Science Source Type: news