Mallinckrodt starts enrolment in Phase lV trial of acthar gel to treat FSGS
Global specialty biopharmaceutical company Mallinckrodt has enrolled patients for its Phase lV clinical trial, PODOCYTE, of acthar gel (repository corticotropin injection) for inducing remission of proteinuria due to treatment-resistant or treatment-… (Source: Drug Development Technology)
Source: Drug Development Technology - May 17, 2016 Category: Pharmaceuticals Source Type: news
Utility of Screening for Proteinuria, Glucosuria, and UTI Throughout Pregnancy With Urine Dipstick for Family Medicine OB Patients at an Academic Center (Pamela Kum MSIV)
(Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded)
Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded - January 19, 2016 Category: Primary Care Source Type: news
Your NEJM Group Today: Proteinuria & Kidney Mass; Antidepressants Overprescribed?; California Hospitalist Opportunities (FREE)
By the Editors
NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today:NEJM Clinical Practice Center: Case Record: … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 17, 2015 Category: Primary Care Source Type: news
Blood Pressure, Proteinuria Reduction Key in IgA NephropathyBlood Pressure, Proteinuria Reduction Key in IgA Nephropathy
For the majority of patients with IgA nephropathy, optimal supportive care is as protective against loss of renal function over time as immunosuppression, data from the STOP-IgAN show. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 12, 2015 Category: Consumer Health News Tags: Nephrology News Source Type: news
How Long Do Creatine Kinase Levels Remain Elevated After Exercise?
Discussion
Acute rhabdomyolysis is an emergency that can cause acute renal failure (especially acute tubular necrosis caused by myoglobinemia) and electrolyte abnormalities. Common presenting findings are dark urine, myalgia and muscle weakness. Milder episodes can go unnoticed. Acute exertional rhabdomyolysis or unrecognized muscle injury can occur in underconditioned persons and even trained athletes who increase their exertion or exercise. Being unaccustomed to the ambient conditions such as heat, humidity and sun can also increase fluid loss and the risk of muscle injury. An overview and differential diagnosis of rhab...
Source: PediatricEducation.org - April 13, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What Causes Proteinuria?
Discussion
Proteinuria occurs relatively often in pediatric practice with 5-15% of school children having transient proteinuria, the most common cause. However, proteinuria can be a sign of kidney disease. Therefore, it is important to evaluate the proteinuria in light of the clinical situation. A good history and physical examination along with a full urinalysis and/or BUN and creatinine, or urine protein/creatinine ratio may be all that is necessary. Another patient with edema, hypertension or hematuria needs a fuller evaluation and treatment. Proteinuria is usually categorized into three groups to assist with evaluation...
Source: PediatricEducation.org - August 18, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Proteinuria often undertreated in hospital settings
Read the full story on MD Consult:
Proteinuria often undertreated in hospital settings (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - May 7, 2014 Category: Journals (General) Source Type: news
Proteinuria Often Untreated in Hospital
LAS VEGAS (MedPage Today) -- Although it's easily managed, proteinuria often goes untreated in the hospital, researchers reported here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 24, 2014 Category: Cardiology Source Type: news
Closer to detecting preeclampsia: Biomarkers found in urine, blood
Researchers have found a set of biomarkers in urine and serum samples that were different between women with preeclampsia, women with normal pregnancies and women who were not pregnant. These biomarkers tell the story of what is happening to the metabolism of women who have developed preeclampsia. Preeclampsia is a disease of pregnancy that has its origins in insufficient development of the placenta during the first trimester, but usually only presents itself close to term, causing high blood pressure (hypertension) and proteins in the urine (proteinuria) of the affected women. The syndrome can be dangerous for both mother...
Source: ScienceDaily Headlines - March 17, 2014 Category: Science Source Type: news
Soft drinks and sugar in the diet may have negative effects on the kidneys
Two new studies highlight the potential negative effects that soft drinks and sugar can have on kidney health. Results of these studies were presented at ASN Kidney Week 2013 at the Georgia World Congress Center in Atlanta, GA. In one study, researchers led by Ryohei Yamamoto, MD, PhD (Osaka Univ Graduate School of Medicine, in Japan) found that consuming at least two soft drinks per day is linked with proteinuria - or increased excretion of protein in the urine, which is a hallmark of kidney dysfunction... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
Orencia Slows Proteinuria in Renal Disease (CME/CE)
ATLANTA (MedPage Today) -- Proteinuria resolved partly or completely in a small group of patients with focal segmental glomerulosclerosis treated with abatacept, according to a study reported here. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - November 9, 2013 Category: Primary Care Source Type: news
New pre-eclampsia test 'shows promise'
Conclusion
The researchers say this is the largest and first prospective study to look at PIGF levels in women with suspected pre-eclampsia.
Overall, this study provides early positive findings of a diagnostic test for use in pregnant women with suspected pre-eclampsia. The researchers point out that it is known that plasma PIGF levels normally decline in the latter part of the third trimester (weeks 29 to 40), which reduces the PIGF test performance after 35 weeks gestation.
All new screening and diagnostic tests need to weigh up the benefits against the risks. The benefits of the test could include earlier detection ...
Source: NHS News Feed - November 5, 2013 Category: Consumer Health News Tags: Pregnancy/child Source Type: news
A high-fat diet induces preeclampsia-like symptoms in pregnant rats
Preeclampsia is a relatively common pregnancy disorder, characterized by primary hypertension and proteinuria. In patients with severe preeclampsia, eclampsia can develop, causing nervous system symptoms and signs. In the clinic, some patients with preeclampsia suffer from eclampsia even with minimal blood pressure changes. Thus, the pathogenesis of hypertensive encephalopathy cannot fully explain the epilepsy-like attacks in eclampsia patients. We know that changes in neurotransmitter levels in the brain play an important role in epilepsy-like attacks... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 11, 2013 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news
Protein In The Urine Linked To Life Expectancy
Pee in a cup and you might get a clue as to how much longer you will live. A new report published online today in the National Kidney Foundation's American Journal of Kidney Diseases shows a strong correlation between levels of protein in the urine, or proteinuria, and mortality. "Our report shows that both men and women with higher levels of proteinuria had substantially reduced life expectancy in comparison to people with relatively low levels of proteinuria," said the report's lead author, Dr. Tanvir Chowdhury Turin of the University of Calgary... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 3, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
Horizon scanning: Drisapersen linked to serious side effects and hospitalisation according to safety data from trial investigating the drug in Duchenne muscular dystrophy
Source: BioSpace
Area: News
BioSpace reports that patients enrolled in an early stage trial investigating the use of drisapersen (GSK-2402968) in Duchenne muscular dystrophy (DMD) have been hospitalised due to kidney toxicity and low platelet counts. The report is based on data presented at a research meeting in Rome. GlaxSmithKline (GSK) has released some safety data from early stage clinical trials previously too and these mainly reported cases of proteinuria and decreased thrombocytes. According to the BioSpace report, four DMD) patients treated with drisapersen required hospitalisation due to thrombocytopenia and "se...
Source: NeLM - News - March 1, 2013 Category: Drugs & Pharmacology Source Type: news
