Bifidobacterium Longum in the Aging Gut Microbiome
This research is a representative example of ongoing efforts to better understand changes in the gut microbiome with age, identifying how and why specific microbial species are either protective or harmful to health. The gut microbiome is responsible for generating a range of helpful metabolites, but can also interact with tissues and the immune system to provoke chronic inflammation. It has been noted that some known beneficial populations decline while some known harmful populations grow in number with advancing age - though there is a great deal of work remaining to produce a full map of the effects of microbial species...
Source: Fight Aging! - September 24, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Leuconostoc mesenteroides
The post Leuconostoc mesenteroides appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - September 19, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora microbiota probiotic undoctored Source Type: blogs

Paleovalley: Our preferred source for fermented beef sticks and other products
    Iā€™d like to welcome my new Defiant Health podcast’s latest sponsor, Paleovalley, makers of absolutely delicious grass-fed beef sticks, healthy snack bars, and other products. You know that we are extremely picky around here and insist that any product we consider has no junk ingredients like maltodextrin, carrageenan, carboxymethylcellulose, sucralose or other additives that have potential adverse health effects. You will not find any such unhealthy ingredients in Paleovalley products. And all Paleovalley products deserve the Defiant Health stamp of approval because they contain no gluten, grains, soy...
Source: Wheat Belly Blog - September 6, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open probiotic undoctored wheat belly Source Type: blogs

Fight Aging! Newsletter, September 6th 2021
In conclusion, patients over 90 years of age had an overall low prevalence of fractures and relative preservation of bone health, suggesting a preserved bone molecular profile in these individuals. Epigenetic factors and activity levels might also have favorably affected bone health. The low percentage of osteoporosis and fractures likely reduced the morbidity and mortality in this population, potentially contributing to their overall longevity. Building a Therapy for Aging Based on SIRT6 Upregulation https://www.fightaging.org/archives/2021/08/building-a-therapy-for-aging-based-on-sirt6-upregulation/ G...
Source: Fight Aging! - September 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fecal Microbiota Transplant as a Treatment for Neurodegenerative Conditions
It is thought that an appreciable fraction of the chronic inflammation of aging is caused by changes in the gut microbiome. There is a bidirectional interaction between the immune system and the microbial populations of the intestinal tract. The immune system gardens these populations, destroying problematic microbes. Microbes secrete metabolites and other molecules that can either benefit or harm the function of the immune system, the harms caused particularly by those microbes capable of provoking a sustained inflammatory response. The immune system declines with age for a range of reasons, and reduced efficacy in immune...
Source: Fight Aging! - September 3, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Are you squeamish about fermentation?
Including fermented foods in your diet is among the most important strategies you can adopt for bowel and overall health. It is so important that I tell people to include at least one, if not many, fermented foods in your daily routine. Fermented foods literally come in thousands of different forms. Among the most familiar are yogurt, kefir, sauerkraut, pickles, and fermented meats like salami and sopressata. (Note that most commercially sold sauerkraut, and pickles in the U.S. are not fermented, but simply packaged in vinegar and brine. Yogurt, and to a lesser degree, kefirs, are fermented for such a short time to hasten ...
Source: Wheat Belly Blog - September 3, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open bowel flora microbiota prebiotic probiotic undoctored wheat belly Source Type: blogs

Belly Farm
The post Belly Farm appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - August 23, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora microbiota probiotic undoctored Source Type: blogs

Fight Aging! Newsletter, August 23rd 2021
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - August 22, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Oxytocin: Superstar for bone and joint health?
The post Oxytocin: Superstar for bone and joint health? appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - August 20, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora joint pain microbiota oxytocin probiotic reuteri undoctored Source Type: blogs

Fecal Microbiota Transplant from Young Mice Improves Cognitive Function in Old Mice
The gut microbiome shifts with age, reducing beneficial populations and increasing harmful populations that contribute to chronic inflammation. Today's research materials can be added to other examples in which an intervention to restore a more youthful gut microbiome in old animals results in improved function, both through a reduction in inflammation and increased production of beneficial metabolites such as butyrate, that promotes increased levels of BDNF and neurogenesis, among other effects. It is a challenge to pick apart which of the mechanisms are most influential, but restoring a more youthful gut microbiome is cl...
Source: Fight Aging! - August 18, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Defiant Health podcast: The Loss of Empathy (and how to bring it back)
I posted the latest episode of my Defiant Health Podcast. You can find it here or through your favorite podcast provider. It is estimated that, as modern humans, we have lost about half of the microbial species we used to harbor in our intestinal microbiomes. The loss of the microbial species Lactobacillus reuteri, in particular, by nearly all modern humans has led to a reduction in production of the hormone oxytocin and thereby a loss of empathy, reduced desire for social connection, an increase in social anxiety, and may be a contributing cause to troubling social phenomena such as social isolation, divorce, and suicide....
Source: Wheat Belly Blog - August 1, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open bowel flora defiant health empathy microbiota oxytocin podcast probiotic reuteri undoctored wheat belly Source Type: blogs

The Age of the Microbiome
The post The Age of the Microbiome appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - July 24, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora microbiota prebiotic probiotic undoctored Source Type: blogs

Recognize markers of endotoxemia
The post Recognize markers of endotoxemia appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - July 14, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat-Free Lifestyle bowel flora Inflammation microbiota prebiotic probiotic undoctored wheat belly Source Type: blogs

Defiant Health: Lost Microbes
I posted the latest episode of my Defiant Health Podcast. You can find it here or through your favorite podcast provider. It is estimated that, as modern humans, we have lost about half of the microbial species we used to harbor in our intestinal microbiomes. Identify, then restore, some of the microbes we’ve lost that were critical for health and wonderful things can happen. You can find Defiant Health on podcast hosting sites such as Stitcher, Spotify, Amazon Music, Podcast Addict, iHeart Radio, and Podchaser. (Apple and Google coming in future.) Be sure to subscribe, post a review, and tell your friends because we...
Source: Wheat Belly Blog - July 7, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open bowel flora defiant health microbiota oxytocin podcast probiotic reuteri undoctored wheat belly Source Type: blogs

L reuteri Yogurt: Do ā€™ s and Don ā€™ ts
The post L reuteri Yogurt: Do’s and Don’ts appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - July 7, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora microbiota probiotic undoctored Source Type: blogs