" Marked " -- The Discovery Files
Many bugs that make us sick--bacteria, viruses, fungi and parasites--hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles while leaving the rest of the living cell intact. Now, researchers from Duke University have discovered that our bodies mark pathogen-containing vacuoles for destruction by using a molecule called ubiquitin, commonly known as the " kiss of death. " (Source: The Discovery Files)
Source: The Discovery Files - November 10, 2015 Category: Science Authors: National Science Foundation Source Type: podcasts
TWiV 356: Got viruses?
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
Guest: Stephanie Neal
Stephanie joins the super professors to discuss the gut virome of children with serious malnutrition, caterpillar genes acquired from parasitic wasps, and the effect of adding chemokines to a simian immunodeficiency virus DNA vaccine.
Links for this episode
Invitrogen Science Hero Awards
Gut DNA viromes of twins with severe malnutrition (PNAS)
Random forests
Wasps engineer caterpillars (PLoS Genetics)
Chemokine-adjuvanted SIV DNA vaccine (Mucos Immunol)
Guide to chemokines (pdf)
Role for CCR10 in IgA se...
Source: This Week in Virology - MP3 Edition - September 27, 2015 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Deworming buffalo and a news roundup
Vanessa Ezenwa discusses the complex relationship between parasitic infections and tuberculosis in African buffalo and what it can tell us about human health. Online news editor David Grimm dicusses coloration in lizards, weighing earth-like planets, and how bears help meadows by eating ants. Hosted by Sarah Crespi. [Img: Mark Jordahl/Flickr/CC-BY-2.0] (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - January 8, 2015 Category: Science Authors: Science Source Type: podcasts
Nature Podcast: 10 April 2014
This week, a nasty parasite that eats cells alive, an ecological experiment floods the Colorado River delta, and the truth behind being an IPCC contributor. (Source: Nature Podcast)
Source: Nature Podcast - April 9, 2014 Category: Science Authors: Nature Publishing Group Source Type: podcasts
Nature Podcast: 10 April 2014
This week, a nasty parasite that eats cells alive, an ecological experiment floods the Colorado River delta, and the truth behind being an IPCC contributor. For information regarding your data privacy, visit acast.com/privacy (Source: Nature Podcast)
Source: Nature Podcast - April 9, 2014 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Nature Podcast: 10 April 2014
This week, a nasty parasite that eats cells alive, an ecological experiment floods the Colorado River delta, and the truth behind being an IPCC contributor. (Source: Nature Podcast)
Source: Nature Podcast - April 9, 2014 Category: Science Authors: Springer Nature Limited Source Type: podcasts
MSF Frontline Reports - June 2009
At least 10 percent of the population in Bolivia is believed to be carrying the parasite for Chagas disease. Few people, including medical staff, are aware of its prevalence, but MSF is running a ground-breaking program there. Also hear how MSF is offering mental health care to those affected by continuing violence on the island of Mindanao in the Philippines. And learn how MSF is providing health care in Balochistan province in Pakistan, where decades of insecurity has made medical services rare. (Source: MSF Podcasts)
Source: MSF Podcasts - April 5, 2014 Category: Global & Universal Authors: Médecins Sans Frontières/Doctors Without Borders (MSF) Source Type: podcasts
TWiV 248: TWiP infects TWiV
Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit
Vincent, Dickson, and Rich reveal how experiments with a malaria parasite lead to the introduction of a mammalian retrovirus into birds.
Links for this episode:
Scientists cast doubt on MERS origin (NY Times)
Animal reservoirs of SARS coronavirus (Virus Res)
Jo Handelsman in the White House
Origins of REV (PLoS Biology)
Inadvertent transfer (virology blog)
Mongoose, pheasant, pox, retrovirus (PLoS Biol)
Evolutionary history of REVs
Amazing story (Ed Yong)
My wife's P. lophurae paper (Mol Bio...
Source: This Week in Virology - MP3 Edition - September 1, 2013 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 214: This is your brain on polyomavirus
Hosts: Vincent Racaniello, Rich Alan Dove, and Kathy Spindler
Vincent, Alan, and Kathy discuss how coagulation factor X binding to adenovirus activates the innate immune system, and a novel polyomavirus associated with brain tumors in raccoons.
Links for this episode:
Coagulation factor X activates innate immunity to adenovirus (Science)
A decorated virus cannot hide (Science)
Reflecting on goals for Science
Polyomavirus associated with raccoon brain tumors (EID)
MPNST
Moore tumor viruses - TWiV 160
Treating CLL with lentivirus vectors (NEJM)
Letters re...
Source: This Week in Virology - MP3 Edition - January 7, 2013 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
