Why do most patients with epithelial cancers not respond to T cell checkpoint blockade?
NCI Center for Cancer Research Eminent Lecture
Over the past 40 years, Dr. Fearon has made contributions to our understanding of innate immunity, B cell signal transduction, memory T cells, and, most recently, cancer immunology. During the past 10 years, Dr. Fearon has trained 15 PhD and MB/PhD students at the University of Cambridge. Former post-doctoral fellows now have faculty or staff positions at outstanding institutions such as Harvard Medical School, the NIAID, University of Cambridge, King’s College London, University of Leicester, and the University of Ryukyus. His past work with a genetically engineered mous...
Source: Videocast - All Events - April 20, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Dissecting KRAS-driven Pancreatic Tumorigenesis
Presented by: Brain Lewis, Ph.D., Associate Professor, Molecular, Cell and Cancer Biology, University of Massachusetts Medical SchoolCategory: NCI CCR Eminent Lectures (HHS Only)Aired date: 03/21/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - March 22, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Dissecting KRAS-driven Pancreatic Tumorigenesis
CCR Eminent Lectures
Dr. Brian Lewis is an Associate Professor in the Department of Molecular, Cell and Cancer Biology at the University of Massachusetts Medical School (UMMS). He is also the Associate Dean for Student Diversity in the Graduate School of Biomedical Sciences at UMMS. Dr. Lewis received his BS in Biology from the University of California, Los Angeles and his PhD, also in Biology, from the Johns Hopkins University. After completing postdoctoral training at the National Institutes of Health and Memorial Sloan-Kettering Cancer Center, Lewis joined the faculty at UM...
Source: Videocast - All Events - March 17, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Predicting the incidence of cancer: Does natural selection pick holographic networks?
Director's Seminar Series
Maintenance of function in many tissues in adult animals requires controlled somatic stem cell replication. The vast majority of these replication events are uneventful, as there are multiple levels of quality control: DNA damage repair mechanisms, paracrine signaling and the extracellular matrix, the immune system, and likely others that have not been uncovered. Our work has modeled tissue development and homeostasis processes in a variety of tissues: adipose tissue, beta cells in the islets of Langerhans, the development of the overall endocrine pancreas, and liver regeneration after partial h...
Source: Videocast - All Events - March 3, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Protein Phosphorylation and Cell Signaling in Cancer
NCI Center for Cancer Research Eminent Lecture
Tony Hunter is the Renato Dulbecco Chair in Cancer Research, Director of the Salk Institute Cancer Center and an American Cancer Society Professor in the Molecular and Cell Biology Laboratory at the Salk Institute for Biological Studies in La Jolla. In 1979, through his work on tumor viruses, he discovered a new class of protein kinase that phosphorylates tyrosine. He has spent most of the last 35 years studying protein kinases and phosphatase, and the role of protein phosphorylation in cell proliferation and the cell cycle, and how aberrant protein phosphorylation can caus...
Source: Videocast - All Events - February 17, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Andrew H. Ko, MD - Treating Newly Diagnosed Metastatic Pancreatic Cancer: An Oncologist ’s View of a Patient’s Story
Treating Newly Diagnosed Metastatic Pancreatic Cancer: An Oncologist’s View of a Patient’s Story (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - January 18, 2016 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Andrew H. Ko, MD - Treating Newly Diagnosed Metastatic Pancreatic Cancer: An Oncologist’s View of a Patient’s Story
Treating Newly Diagnosed Metastatic Pancreatic Cancer: An Oncologist’s View of a Patient’s Story (Source: Peerview CME/CE Video Podcast - Gastroenterology)
Source: Peerview CME/CE Video Podcast - Gastroenterology - January 18, 2016 Category: Gastroenterology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
TRACO 2015: Nanotechnology - Pancreatic Cancer
Presented by: M. Dobrovolskaia, NIH; P. Hussain, NIHCategory: TRACOAired date: 11/30/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - December 1, 2015 Category: Journals (General) Tags: Past Events Source Type: video
Forcing Tumor Progression
NCI’s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Dr. Valerie Weaver is the Director of the Center for Bioengineering and Tissue Regeneration in the Surgery Department. She also jointly oversees the UCSF Brain Tumor Microenvironment Program and co-directs the Bay Area Physical Sciences and Oncology Program. During Dr. Weaver’s tenure at LBNL she was awarded a California Breast Cancer Research Grant and received a Distinguished LBNL Scientist award for he...
Source: Videocast - All Events - November 9, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
TRACO 2015: Nanotechnology - Pancreatic Cancer
Nanotechnology; Pancreatic cancerFor more information go to http://ccr.cancer.gov//trainee-resources-courses-workshops-tracoAir date: 11/30/2015 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 5, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
TRACO 2014 - Nanotechnology; Pancreatic cancer
Presented by: Dobrovolskaia, M.; Hussain, P.Category: TRACOAired date: 12/08/2014 (Source: Videocast - All Events)
Source: Videocast - All Events - December 9, 2014 Category: Journals (General) Tags: Past Events Source Type: video
Normalizing the Tumor Microenvironment to Enhance Cancer Treatment
Wednesday Afternoon Lecture Series
For more than three decades, Dr. Jain's laboratory research has focused on one challenge: improving the delivery and efficacy of anti-cancer therapies. Working on the hypothesis that the abnormal tumor microenvironment fuels tumor progression and treatment resistance, the Jain laboratory has developed an array of novel imaging technologies and animal models as well as mathematical models to unravel the complex biology of tumors. They demonstrated that the blood and lymphatic vasculature, fibroblasts, immune cells, and the extracellular matrix associated with tumors are abnormal and togeth...
Source: Videocast - All Events - October 21, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video
TRACO 2014 - Nanotechnology; Pancreatic cancer
TRACO
Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in development and implementation of many new technologies, such as nanotechnology, next generation sequencing, genomics and proteomics.
For...
Source: Videocast - All Events - August 18, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video
TRACO - Nanotechnology - Pancreatic Cancer
Presented by: M. Dobrovolskaia; P. HussainCategory: TRACOAired date: 12/09/2013 (Source: Videocast - All Events)
Source: Videocast - All Events - December 17, 2013 Category: Journals (General) Tags: Past Events Source Type: video
TRACO - Nanotechnology - Pancreatic Cancer
Nanotechnology; Pancreatic cancerFor more information go to http://ccr.cancer.gov/careers/courses/tracoAir date: 12/9/2013 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 6, 2013 Category: Journals (General) Tags: Upcoming Events Source Type: video
