A New Brain Measure of Nociception in Infants | Pain Research Forum
Unlike adults, infants can't tell you if they're in pain. Instead, clinicians must interpret behaviors such as crying and physiological measures such as heart rate to determine what a newborn is experiencing. Since these can occur for reasons unrelated to nociception, the pain field has long sought more objective ways to measure pain in this nonverbal population. Now, in a new study, investigators have identified pain-related brain activity in infants that could be measured with a simple electroencephalogram (EEG) recording and used the activity to create an EEG template that allowed them to test the efficacy of an...
Source: Psychology of Pain - August 24, 2017 Category: Anesthesiology Source Type: blogs

New 3D Printing Method to Create Complex, Multi-Cellular Tissues
Researchers from University of Oxford have been working to overcome some of the major challenges of 3D printing living tissues and have just published a report of how they were able to create complex, multi-cellular structures that stay viable and are able to structurally support themselves. This high density bioprinting process is also cheap, reliable, and can be adapted to work with different cell types and target structures, perhaps opening the door to new therapies for a wide variety of diseases and conditions. In order for the living cells to be able to combine into a coherent structure instead of a messy pile, the r...
Source: Medgadget - August 16, 2017 Category: Medical Devices Authors: Editors Tags: Genetics Source Type: blogs

Trial by Error: The Science Media Centre ’ s Desperate Efforts to Defend PACE
By David Tuller, DrPH This week, the Journal of Health Psychology published a special issue containing a raft of commentaries on the PACE trial. Most of them slammed the study for its many, many unacceptable flaws. Not surprisingly, Sir Simon Wessely’s lackeys at the Science Media Centre immediately posted three comments from “experts” lauding the trial and criticizing the JHP commentaries. I thought it might be helpful to deconstruct these rather pathetic efforts at defending the indefensible. I’ve posted all three statements below, followed by my comments. I decided to keep them relatively brief, although I ...
Source: virology blog - August 2, 2017 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Brain Death – 3rd Edition by Wijdicks
Oxford University Press has just published the 3rd edition of Brain Death by the leading expert on brain death, Eelco F.M. Wijdicks. Brain Death provides a practical, comprehensive, clinical resource for practitioners seeing patients with acut... (Source: blog.bioethics.net)
Source: blog.bioethics.net - July 20, 2017 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

The Ethics of Treatment for Charlie Gard: Resources for Students/Media
My colleagues over at the University of Oxford Practical Ethics Blog have collected together below some of the materials on the Charlie Gard case that they and others have written as well as some relevant  resources from thei... (Source: blog.bioethics.net)
Source: blog.bioethics.net - July 17, 2017 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

This is your brain on alcohol
It’s no secret that alcohol affects our brains, and most moderate drinkers like the way it makes them feel — happier, less stressed, more sociable. Science has verified alcohol’s feel-good effect; PET scans have shown that alcohol releases endorphins (the “pleasure hormones”) which bind to opiate receptors in the brain. Although excessive drinking is linked to an increased risk of dementia, decades of observational studies have indicated that moderate drinking — defined as no more than one drink a day for women and two for men — has few ill effects. (A drink equals 1.5 ounces of 80-proof spirits, 5 ounces of ...
Source: Harvard Health Blog - July 14, 2017 Category: Consumer Health News Authors: Beverly Merz Tags: Addiction Brain and cognitive health Healthy Eating Heart Health Memory Source Type: blogs

ECG interpretation
In my last post I mentioned ECGs.And as well as the book mentioned in the last post, there are the various books by John Hampton:ECG made easy150 ECG casesECG in practiceLook for them in your library!But there are limitations to books when it comes to teaching and learning interpretation of ECGs.  That is pointed out on the ECG Wave-Maven site, used as the source of ECGs at the Cardiology education meeting I have just returned from:Nathanson LA, McClennen S, Safran C, Goldberger AL. ECG Wave-Maven: Self-Assessment Program for Students and Clinicians.http://ecg.bidmc.harvard.edu.You can browse a case list, with or with...
Source: Browsing - June 16, 2017 Category: Databases & Libraries Tags: cardiology Source Type: blogs

Rape, disability, and gender: A response to McMahan and Singer ’s op-ed on the Anna Stubblefield case
Unfortunately, there have been numerous cases of sexual harassment and sexual assault in academia and particularly in more male-dominated fields, including my home field of philosophy. In these cases, professors use their position of prestige and power to sexually harass and abuse their students. UC Berkeley philosophy professor John Searle is just the most recent example. To my knowledge, all of these cases have involved male professors victimizing female students. The lone exception is Anna Stubblefield, a former professor of philosophy at Rutgers. Here is a summary of her case from Current Affairs:  At issue is the...
Source: blog.bioethics.net - April 12, 2017 Category: Medical Ethics Authors: Bioethics Today Tags: Health Care consent disability Sex and Sexuality syndicated Source Type: blogs

Will Data Aggregation For Precision Medicine Compromise Patient Privacy?
Like anyone else who follows medical research, I’m fascinated by the progress of precision medicine initiatives. I often find myself explaining to relatives that in the (perhaps far distant) future, their doctor may be able to offer treatments customized specifically for them. The prospect is awe-inspiring even for me, someone who’s been researching and writing about health data for decades. That being the case, there are problems in bringing so much personal information together into a giant database, suggests Jennifer Kulynych in an article for OUPblog, which is published by Oxford University Press. In particular, ...
Source: EMR and HIPAA - April 10, 2017 Category: Information Technology Authors: Anne Zieger Tags: EHR Electronic Health Record Electronic Medical Record EMR EMR Security Genomic Health Record Healthcare HealthCare IT HIPAA General Hospital EHR Medical Privacy Personalized Medicine Precision Medicine Big Data De-Identified P Source Type: blogs

An open letter to Psychological Medicine, again!
In conclusion, noted Wilshire et al., “the claim that patients can recover as a result of CBT and GET is not justified by the data, and is highly misleading to clinicians and patients considering these treatments.” In short, the PACE trial had null results for recovery, according to the protocol definition selected by the authors themselves. Besides the inflated recovery results reported in Psychological Medicine, the study suffered from a host of other problems, including the following: *In a paradox, the revised recovery thresholds for physical function and fatigue–two of the four recovery measures–were so lax ...
Source: virology blog - March 23, 2017 Category: Virology Authors: Vincent Racaniello Tags: Commentary Information adaptive pacing therapy CFS chronic fatigue syndrome clinical trial cognitive behavior therapy Dave Tuller exercise graded exercise therapy mecfs myalgic encephalomyelitis outcome PACE trial recovery Source Type: blogs

Circle time rituals help children beat the Marshmallow Test of self control
By Christian Jarrett Sweet, old-fashioned circle time rituals involve young children sitting in a circle with a teacher and copying his or her specific actions as closely as possible. These rituals can seem a bit out of place in today’s culture with its emphasis on the importance of independent thinking, and the ubiquity of interactive educational games employing the latest beeps and whistles of technology. But a new study in Child Development says there is something about the conformity and attention to detail in ritualistic games that makes them a highly effective way to improve children’s executive functi...
Source: BPS RESEARCH DIGEST - March 3, 2017 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Developmental Educational Source Type: blogs

Rio's Olympic Disaster
“The legacy of the Rio Olympics is a farce,”writes sports columnist Nancy Armour inUSA Today. She continues:The closing ceremony was six months ago Tuesday, and already several of the venues are abandoned and falling apart. The Olympic Park is a ghost town, the lights have been turned off at the Maracana and the athlete village sits empty …. the billions that were wasted, the venues that so quickly became white elephants, the crippling bills for a city and country already struggling to make ends meet…She notes that more and more cities are realizing that Olympic games are glamorous but not economically sound. Imade...
Source: Cato-at-liberty - February 23, 2017 Category: American Health Authors: David Boaz Source Type: blogs

What is pain for?
We’re told we need pain – without the experience, we risk harming our bodies and living short lives. With pain, and for most people, we learn to not go there, don’t do that, don’t do that AGAIN, and look at that person – don’t do what they’re doing! Thirst, hunger, fear, delicious tastes and smells, the feelings of belonging, of safety and security, of calm and comfort: all of these are experiences we learn about as we develop greater control over our bodies. Pain is an experience we learn to associate with actual or possible threat to “self”. Let’s take a moment ...
Source: HealthSkills Weblog - February 19, 2017 Category: Anesthesiology Authors: adiemusfree Tags: Coping strategies Pain Pain conditions Resilience/Health acceptance biopsychosocial Clinical reasoning Research Therapeutic approaches values Source Type: blogs

Religion and Futility in the ICU
The University of Oxford Faculty of Philosophy are hosting an event on Monday, May 8, 2017:  "Religion and Futility in the Intensive Care Unit."  This is a half-day seminar exploring issues around religion, pluralism and medical ethics. A child is critically ill in the intensive unit. Doctors believe that the child’s prognosis is very poor and that treatment should be withdrawn. However, her parents do not agree. They say that it is contrary to their religion to stop treatment. How often is religion a source of disagreement about treatment in intensive care? What are the views of major religions about withd...
Source: blog.bioethics.net - February 17, 2017 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care medical futility blog syndicated Source Type: blogs

Health Affairs ’ February Issue: The Work/Health Relationship
The February issue of Health Affairs contains a collection of papers about the complex work/health relationship. Work conditions can affect employees’ physical and mental health, and worker productivity can be affected by the demands employees face after returning home from the office. The issue is supported by the Integrated Benefits Institute, Sedgwick, and UnitedHealth Group, as well as Pfizer and Pinnacol Assurance. Check out Health Affairs’ newest web hub: Obamacare to Trumpcare. Key health policy questions are explored for the Affordable Care Act (ACA), Medicare, Medicaid, and payment reform. Will low-income mino...
Source: Health Affairs Blog - February 6, 2017 Category: Health Management Authors: Health Affairs Tags: Elsewhere@ Health Affairs Featured Health Affairs journal work and health Source Type: blogs