Gabapentin May Cut Opioid Needs for Oral Mucositis Pain During RT
Findings seen in studies involving patients receiving chemoradiotherapy for nonmetastatic squamous cell carcinoma of head and neck (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 12, 2017 Category: Cancer & Oncology Tags: Oncology, ENT, Pharmacy, Radiology, Anesthesiology & amp; Pain, Journal, Source Type: news
Antiepileptic Med Use Increasing in Nursing Home Residents With Dementia
The two most common, valproic acid and gabapentin, being used in clinically distinct ways (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 12, 2017 Category: Psychiatry Tags: Internal Medicine, Neurology, Nursing, Pharmacy, Psychiatry, Geriatrics, Journal, Source Type: news
Gabapentin Plus Opioids a Deadly Combination? Gabapentin Plus Opioids a Deadly Combination?
The risk for opioid-related death was 49% higher in patients recently exposed to gabapentin and opioids compared to those exposed to opioids alone.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 4, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news
Combined use of opioids and gabapentin substantially increases risk of overdose
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - October 3, 2017 Category: Hospital Management Tags: Hospital News Source Type: news
Gabapentin co-use may increase risk of fatal opioid overdose
(PLOS) Co-prescription of the anticonvulsant gabapentin is associated with an increased risk of opioid-related death in people who are prescribed opioid painkillers, according to a new study published in PLOS Medicine. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 3, 2017 Category: Biology Source Type: news
New Reports Show Rising Gabapentin Misuse and Abuse
Recent studies show increasing misuse of gabapentin, with prevalence as high as 68% among those with opioid use disorders. Novus Medical Detox Center urges the DEA and FDA to classify the drug as a...(PRWeb August 21, 2017)Read the full story at http://www.prweb.com/releases/2017/08/prweb14616314.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - August 21, 2017 Category: Pharmaceuticals Source Type: news
Gabapentinoids Ineffective for Chronic Low Back Pain Gabapentinoids Ineffective for Chronic Low Back Pain
The gabapentinoids pregabalin and gabapentin are not effective in treating chronic low back pain (CLBP), according to a systematic review and meta-analysis.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 16, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news
Scientists discover powerful potential pain reliever
(University of Texas at Austin) Chemists have discovered a powerful pain reliever that acts on a previously unknown pain pathway. The compound is as effective at relieving neuropathic pain in injured mice as a drug widely used for pain relief called gabapentin. If they can demonstrate that it is safe, effective and nonaddictive in humans -- a process that typically takes years -- the discovery could address one of today's biggest public health challenges: the opioid abuse epidemic. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 16, 2017 Category: International Medicine & Public Health Source Type: news
Your NEJM Group Today: Concerns About Gabapentin for Pain / PPIs & Dementia / California IM Opportunity (FREE)
By the Editors
Take a look at today ' s offering from NEJM Group:NEJM Audio Interview: Treating Pain with Gabapentinoids: Dr. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 3, 2017 Category: Primary Care Source Type: news
Gabapentin and Postoperative Respiratory Depression Gabapentin and Postoperative Respiratory Depression
When included in multimodal analgesic regimens, is gabapentin associated with respiratory depression during post-anesthesia recovery after major laparoscopic procedures?Anesthesia & Analgesia (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 27, 2017 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news
Morning Break: Opioid-Neurontin Cocktails; Keytruda Trial Deaths
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - July 6, 2017 Category: Psychiatry Source Type: news
miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes
Nociception is protective and prevents tissue damage but can also facilitate chronic pain. Whether a general principle governs these two types of pain is unknown. Here, we show that both basal mechanical and neuropathic pain are controlled by the microRNA-183 (miR-183) cluster in mice. This single cluster controls more than 80% of neuropathic pain–regulated genes and scales basal mechanical sensitivity and mechanical allodynia by regulating auxiliary voltage-gated calcium channel subunits α2-1 and α2-2. Basal sensitivity is controlled in nociceptors, and allodynia involves TrkB+ light-touch mechanorecepto...
Source: ScienceNOW - June 15, 2017 Category: Science Authors: Peng, C., Li, L., Zhang, M.-D., Bengtsson Gonzales, C., Parisien, M., Belfer, I., Usoskin, D., Abdo, H., Furlan, A., Häring, M., Lallemend, F., Harkany, T., Diatchenko, L., Hökfelt, T., Hjerling-Leffler, J., Ernfors, P. Tags: Neuroscience reports Source Type: news
Law enforcement-derived data on gabapentin diversion and misuse, 2002-2015: diversion rates and qualitative research findings - Buttram ME, Kurtz SP, Dart RC, Margolin ZR.
PURPOSE: Recent limited epidemiologic and case reports suggest that gabapentin is being misused, especially among prescription opioid misusers. However, no apparent studies have reported data from law enforcement on the diversion and misuse of gabapentin. ... (Source: SafetyLit)
Source: SafetyLit - May 19, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
