La FDA advierte acerca de problemas respiratorios graves con los medicamentos para convulsiones y dolor neural gabapentina (Neurontin, Gralise, Horizant) y pregabalina (Lyrica, Lyrica CR)
La Administraci ón de Alimentos y Medicamentos de EE. UU. (FDA) advierte que los pacientes con factores de riesgo respiratorio que usan gabapentina (Neurontin, Gralise, Horizant) o pregabalina (Lyrica, Lyrica CR) pueden sufrir graves dificultades respiratorias. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 30, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Withdrawal, dependence and adverse events of antidepressants: lessons from patients and data
Tolerability, withdrawal effects and dependence on prescription medication is an important topic of current scientific and clinical debate, as highlighted by the recent report published on September 2019 by Public Health England (https://www.gov.uk/government/publications/prescribed-medicines-review-report).1 This was a mixed methods public health review of available evidence in adults focusing on specific issues of dependence and withdrawal associated with five groups of medications: (1) benzodiazepines, (2) z-drugs, (3) gabapentin and pregabalin, (4) opioids and (5) antidepressants. The evidence included in the review co...
Source: Current Awareness Service for Health (CASH) - January 24, 2020 Category: Consumer Health News Source Type: news

Low-Dose Gabapentin in Combination with Methadone May Improve QOL in Patients with HNC
Administering a high dose of gabapentin also increased the percentage of patients who required no opioid during treatment, indicating that patients were possibly gleaning benefits from gabapentin in both treatment arms. (Source: CancerNetwork)
Source: CancerNetwork - January 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Study: Misuse of Certain Nonopioid Analgesics on the Rise
Research suggests that as the number of prescriptions written for opioids has dropped, there has been a corresponding rise in the use of nonopioid medications such as gabapentin and baclofen to treat certain types of pain. (Source: AAFP News)
Source: AAFP News - January 9, 2020 Category: Primary Care Source Type: news

FDA warns about serious breathing problems with seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR)
Listen to an audio podcast of the December 19, 2019 FDA Drug Safety Communication warning that serious breathing difficulties may occur in patients using seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR) who have respiratory risk factors. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 2, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Off-Label Use of Gabapentinoids: A New Paradigm
Several of the hot topics in geriatrics are pain management, medication reduction/deprescribing, and use of off-label medications. Best-practice use of gabapentinoids — gabapentin (Neurontin) and pregabalin (Lyrica) — comfortably fits into all three categories. Examination of the evidence may help health care practitioners make better decisions when prescribing these medications. (Source: Caring for the Ages)
Source: Caring for the Ages - December 25, 2019 Category: Health Management Authors: Daniel Haimowitz, Jeanne Manzi Source Type: news

Gabapentin, Opioids a Deadly Duo: FDA
The decision to order the new warnings is based on a review of data from numerous sources, including case reports, observational studies, human trials and animal studies. (Source: WebMD Health)
Source: WebMD Health - December 20, 2019 Category: Consumer Health News Source Type: news

FDA Warns of 'Serious' Problems With Gabapentin
FDA Warns of 'Serious' Respiratory Problems With Gabapentin (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 20, 2019 Category: General Medicine Source Type: news

Neurontin, Gralise, Horizant (gabapentin) and Lyrica, Lyrica CR (pregabalin): Drug Safety Communication - Serious Breathing Problems
FDA is warning that serious breathing difficulties may occur in patients using gabapentin or pregabalin who have respiratory risk factors. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 20, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Warns of'Serious' Respiratory Problems With Gabapentin FDA Warns of'Serious' Respiratory Problems With Gabapentin
The FDA is warning of serious, life-threatening respiratory problems associated with gabapentin.News Alerts (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - December 19, 2019 Category: Primary Care Tags: Neurology & Neurosurgery News Alert Source Type: news

Misuse of Nonopioid Medications Appears to Be on the Rise in U.S.
Increases seen for misuse/abuse, suicide attempts, and hospitalizations linked to gabapentin, baclofen (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - December 19, 2019 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Emergency Medicine, Nursing, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news

FDA warns about serious breathing problems with seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR)
Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Watch for breathing issues, confusion, dizziness, or extreme sleepiness. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 19, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Misuse of Nonopioid Medications Appears to Be on the Rise in U.S.
THURSDAY, Dec. 19, 2019 -- Misuse/abuse, use in suicide attempts, and hospital admissions associated with gabapentin and baclofen have significantly increased among U.S. adults since 2013, according to a study published online Dec. 1 in Clinical... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 19, 2019 Category: Pharmaceuticals Source Type: news

Trends in gabapentin and baclofen exposures reported to U.S. poison centers - Reynolds K, Kaufman R, Korenoski A, Fennimore L, Shulman J, Lynch M.
Context: Prescriptions for nonopioid pharmacological therapies such as gabapentin and baclofen have been increasing. While gabapentin and baclofen are less likely than opioids to result in fatal overdose, they are each associated with dependence, mi... (Source: SafetyLit)
Source: SafetyLit - December 5, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

A common drug could help restore limb function after spinal cord injury
(Ohio State University) Long-term treatment with gabapentin, a commonly prescribed drug for nerve pain, could help restore upper limb function after a spinal cord injury, new research in mice suggests. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 3, 2019 Category: International Medicine & Public Health Source Type: news