November 2021: Fleshy Lumps on the Scalp
Nausea and body aches. Probably COVID. Unvaccinated. Definitely COVID. After all, what else are we seeing?The 20-something young man was eating and talking on his phone. He passed the look test. His vitals were pristine, but he regaled me with myriad symptoms he had had for months. He hadn't taken any medicine. I was at a loss for what drove him to come to the emergency department. He thought for a minute and said, "I want to know why I have all these."He pointed to a spot on his head, which drew my attention to a fleshy lump. Then he moved his hair around, causing others to appear. "You can feel lots more,&...
Source: Lions and Tigers and Bears - November 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

3D Printed Titanium Implants for Severe Spinal Deformities
Most medical implants are manufactured in quantity to cover large groups of people suffering from specific diseases. Those with rare conditions are often left out, but 3D printing, also known as additive manufacturing, now allows for the production of bespoke devices designed exclusively for individual patients. While 3D printing technology has advanced significantly over the past few decades, significant clinical and legal challenges exist that prevent its wider adoption in many spheres of medicine. A diverse group of engineers, surgeons, and regulatory experts have been working together at the University Medical Cente...
Source: Medgadget - July 26, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Orthopedic Surgery Radiology Source Type: blogs

Abdominal wall mass –MRI Approach
50 yr old lady presents for CEMRI with abdominal wall mass in USG with no history of trauma / fever / surgery.CEMRI shows – Large intense& heterogeneously enhancing altered signal intensity space occupying lesion involving left anterior parietes of abdominal wall extending from supraumbilical to pelvic region with areas of necrosis/ restricted diffusion /predominantly edematous signal components /rectus abdominis not separately identified / properitoneal fat stranding with no intraperitoneal extension / across midline /no definite skin ulceration /regional lymphadenopathy / air /MR demonstrable calcification / f...
Source: Sumer's Radiology Site - February 24, 2019 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Tuberous Sclerosis : Case Report
DiscussionTuberous sclerosis is an autosomal dominant neurocutaneous syndrome characterized by various abnormalities, including multisystemic hamartomas. Also known as Bourneville disease, named after D ésiré-Magloire Bourneville, the French physician who discovered the potato like appearance of cortical lesions in the brains of patients with this condition.Tuberous sclerosis is the second most common phakomatosis behind neurofibromatosis type 1. It has a prevalence estimated to be 1 in 6000. App roximately one third of cases of tuberous sclerosis are familial the other two thirds of cases are sporadic and due to spontan...
Source: Sumer's Radiology Site - July 12, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Best Post of January 2018: Choroidal ganglioneuronal hamartoma in an NF1 patient
The next in our " Best of the Month " series is from January 30, 2018:Thanks to Dr. Ahmed Gilani (pediatric pathology fellow at the University of Colorado) for providing me with slides of an enucleation specimen from a patient with Von Recklinghausen Neurofibromatosis (NF-1). The specimen exhibits a region of choroidal expansion with hamartomatous neuroglial tissue. Distributed throughout this choroidal expansion are non-pigmented ovoid bodies, which have a delicately laminated appearance reflecting the presence of concentric Schwann cell processes. One might conceive of these choroidal expansions as cousins of iridic Lisc...
Source: neuropathology blog - March 21, 2018 Category: Radiology Tags: Best of the Month series eye Source Type: blogs

Choroidal ganglioneuronal hamartoma in an NF1 patient
Thanks to Dr. Ahmed Gilani (pediatric pathology fellow at the University of Colorado) for providing me with slides of an enucleation specimen from a patient with Von Recklinghausen Neurofibromatosis (NF-1). The specimen exhibits a region of choroidal expansion with hamartomatous neuroglial tissue. Distributed throughout this choroidal expansion are non-pigmented ovoid bodies, which have a delicately laminated appearance reflecting the presence of concentric Schwann cell processes. One might conceive of these choroidal expansions as cousins of iridic Lisch nodules.Choroidal expansion in an enucleation specimen from a child ...
Source: neuropathology blog - January 30, 2018 Category: Radiology Tags: eye Source Type: blogs

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): MRI
Discussionby Dr MGK Murthy, Dr GA PrasadChronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is characterized clinically by a progressive or relapsing course of many months to years of symptoms similar to compressive myelopathy.Etiology Remains unknown, but T-cell activation in nerves plays an important role in the pathogenesis of CIDP& antigens in Schwann cells have been identified.PathologicallyCIDP is characterized by mononuclear cell infiltrates, edema, segmental demyelination, and remyelination&“onion bulb formation” which describes enlarged fascicles with increased endoneural connective t...
Source: Sumer's Radiology Site - December 12, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Why does hair turn gray?
Follow me on Twitter @RobShmerling If you look at photos of President Obama taken before he ran for president and since he left office, you’ll notice a distinct difference: where there used to be only dark brown hair, there is now far more gray than brown. It seems that the stress of running a country would turn any person’s hair gray. But is stress really to blame? And why does hair turn gray, even for those of us who don’t have jobs quite as stressful as President of the United States? Stress doesn’t actually turn hair gray. In fact, hair doesn’t actually “turn” gray. Once a hair follicle produces hair, the...
Source: Harvard Health Blog - September 18, 2017 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Healthy Aging Skin and Hair Care Source Type: blogs

Beauty is in the Eye
Our eyes are the gateway to countless brilliant sights. However, as evidenced by the images on this page, the eye itself can be breathtakingly exquisite as well. This May, as we celebrate Healthy Vision Month with the National Eye Institute, we hope sharing the beauty hidden in your eyes will inspire you to take the necessary steps to protect your vision, prevent vision loss and make the most of the vision you have remaining. Visit NEI to learn more about caring for your eyes. Happy Healthy Vision Month! Eyes are beautiful, and they take on a whole new look in this agate-like image, which highlights just how complex mamma...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 16, 2017 Category: Research Authors: Kathryn Calkins Tags: Cell Biology Cellular Imaging Cellular Processes Cool Images Source Type: blogs

Fight Aging! Newsletter, May 15th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - May 14, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Exploration of Mechanisms of Hair Greying, but not Yet Linked to Aging
This research is an example of the way in which both the mainstream press and research publicity materials are sometimes quite terrible. The researchers involved have explored some of the cellular biochemistry that is necessary to the pigmentation of hair. They demonstrate, as you might expect, that sabotaging these mechanisms results in grey hair. What they have not yet accomplished is to show that aging has an impact on the specific mechanisms examined in this research. Maybe it does, maybe it doesn't. While the research looks like a promising lead, all things considered, age-related graying of hair might well be caused ...
Source: Fight Aging! - May 10, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Funtabulously Frivolous Friday Five 172
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 172. This week we have an animal based radiology quiz sourced from radiopaedia.org.  Question 1 What animal is winking at you? + Reveal the Funtabulous Answer expand(document.getElementById('ddet1221041592'));expand(document.getElementById('ddetlink1221041592')) An owl It is in reference to an absent pedicle. Differentials include, congenital absence, neurofibromatosis, radiation therapy, spinal metastases, int...
Source: Life in the Fast Lane - January 12, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five achalasia birds beak butterflies cobra head fractures owl pedicle Pulmonary Oedema radiopaedia.org rats tail stag stag antlers ureterocele winking owl sign Source Type: blogs

Neurofibromatosis-I
Patient with multiple cutaneous lesions on MRI brain shows evidence of thickened and moderately T2 hyperintense optic chiasma with moderate post gadolinium enhancement anteriorly extending till the orbital apex. This may indicate optic glioma. There are areas of T2/FLAIR hyperintensity in the bilateral mesial  temporal regions, right globus pallidus region and right pontomesencephalic region, with no significant enhancement, Possible hamartomas. These findings along with cutaneous findings described could indicate diagnosis of Neurofibromatosis I.  Advised clinical correlation. The criteria for the diagnosis...
Source: Sumer's Radiology Site - July 1, 2014 Category: Radiologists Authors: Sumer Sethi Source Type: blogs

Laboratory Abnormalities and Pyloric Stenosis
The classic clinical presentation of infantile hypertrophic pyloric stenosis (IHPS) is an emaciated 3- to 6-week-old infant who has been experiencing immediate postprandial, nonbilious, projectile vomiting over a period of weeks. The infants remain hungry and demand to be re-fed after vomiting. Caucasian, full-term boys (4:1 to 6:1) tend to present with this condition most frequently, and these patients tend to be firstborns. An olive-sized tumor can be felt to the right of the umbilicus, and this may best be palpable immediately after the infant has vomited. Visible peristaltic waves may also be noted. The infants are typ...
Source: M2E Too! Mellick's Multimedia EduBlog - February 28, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Laboratory Abnormalities and Pyloric Stenosis
The classic clinical presentation of infantile hypertrophic pyloric stenosis (IHPS) is an emaciated 3- to 6-week-old infant who has been experiencing immediate postprandial, nonbilious, projectile vomiting over a period of weeks. The infants remain hungry and demand to be re-fed after vomiting. Caucasian, full-term boys (4:1 to 6:1) tend to present with this condition most frequently, and these patients tend to be firstborns. An olive-sized tumor can be felt to the right of the umbilicus, and this may best be palpable immediately after the infant has vomited. Visible peristaltic waves may also be noted. The infants are ty...
Source: M2E Too! Mellick's Multimedia EduBlog - February 28, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs