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European Commission approves Roche ’s Kadcyla for the adjuvant treatment of people with HER2-positive early breast cancer with residual invasive disease after neoadjuvant treatment
Basel, 19 December 2019 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Commission has approved Kadcyla ® (trastuzumab emtansine) for the adjuvant (after surgery) treatment of adult patients with HER2-positive early breast cancer (eBC) who have residual invasive disease in the breast and/or lymph nodes after neoadjuvant (before surgery) taxane-based and HER2-targeted therapy.“Optimal treatment is vital for every patient with early-stage breast cancer, a setting where cures are possible,” said Levi Garraway, M.D., Ph.D., Roche’s Chief Medical Officer and Head of Global Product Development. “T...
Source: Roche Investor Update - December 19, 2019 Category: Pharmaceuticals Source Type: news

European Commission approves Roche ’s Kadcyla for the adjuvant treatment of people with HER2-positive early breast cancer with residual invasive disease after neoadjuvant treatment
Basel, 19 December 2019 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Commission has approved Kadcyla ® (trastuzumab emtansine) for the adjuvant (after surgery) treatment of adult patients with HER2-positive early breast cancer (eBC) who have residual invasive disease in the breast and/or lymph nodes after neoadjuvant (before surgery) taxane-based and HER2-targeted therapy.“Optimal treatment is vital for every patient with early-stage breast cancer, a setting where cures are possible,” said Levi Garraway, M.D., Ph.D., Roche’s Chief Medical Officer and Head of Global...
Source: Roche Media News - December 19, 2019 Category: Pharmaceuticals Source Type: news

Omit Surgery in Early-Stage Breast Cancer? Not Yet Omit Surgery in Early-Stage Breast Cancer? Not Yet
It ' s an enticing idea in an age of breast cancer treatment de-escalation: omit surgery if a patient achieves what looks like a complete response to neoadjuvant chemotherapy.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 17, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Julia White, MD, Discusses Tailored Local Therapy Treatment in Breast Cancer
The professor of radiation oncology discussed these tailored treatments for when patients receive neoadjuvant chemotherapy, and they get a complete pathologic response. (Source: CancerNetwork)
Source: CancerNetwork - December 17, 2019 Category: Cancer & Oncology Authors: Julia White, MD Source Type: news

Promising New Neoadjuvant Strategy in Luminal B Breast Cancer Promising New Neoadjuvant Strategy in Luminal B Breast Cancer
The combination of ribociclib and letrozole proved to a viable alternative to standard multidrug neoadjuvant chemotherapy for women with high-risk luminal B breast cancer in an exploratory phase 2 trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 16, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Research affirms imaging technique's ability to characterize healthy and non-healthy tissue
(SPIE--International Society for Optics and Photonics) In an article published in the peer-reviewed SPIE publication Journal of Biomedical Optics (JBO), 'Influence of neoadjuvant chemotherapy on diffuse reflectance spectra of tissue in breast surgery specimens,' research observed across 92 ex vivo breast specimens suggests that there is little to no impact on the optical signatures of breast tissue after neoadjuvant chemotherapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 27, 2019 Category: Cancer & Oncology Source Type: news

Neoadjuvant Chemotherapy for Primary Sarcoma of the Breast Neoadjuvant Chemotherapy for Primary Sarcoma of the Breast
This case suggests that breast sarcomas could be treated in the same way as other soft tissue sarcomas in terms of adjuvant chemotherapy.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 20, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Laparoscopic Procedures Provide Better Outcomes in Gastric Cancer
Laparoscopy-assisted distal gastrectomy offered better short-term, post-surgical outcomes for patients with locally advanced gastric cancer who were undergoing neoadjuvant chemotherapy. (Source: CancerNetwork)
Source: CancerNetwork - October 8, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Laparoscopic Gastrectomy May Be Preferable After Gastric-Cancer Chemo Laparoscopic Gastrectomy May Be Preferable After Gastric-Cancer Chemo
In patients with locally advanced gastric cancer, laparoscopy-assisted distal gastrectomy (LADG) after neoadjuvant chemotherapy appears to offer more short-term benefits than does open gastrectomy, according to Chinese researchers.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 8, 2019 Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news

Pembrolizumab Plus Chemo Boosts Response in Triple-Negative Breast Cancer
Adding the immunotherapy pembrolizumab to neoadjuvant chemotherapy improved the pathological complete response rate in patients with early triple-negative breast cancer, according to findings of a study presented at ESMO. (Source: CancerNetwork)
Source: CancerNetwork - September 30, 2019 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Lymphedema After Axillary Node Dissection Linked With Obesity, Longer Neoadjuvant Chemo Lymphedema After Axillary Node Dissection Linked With Obesity, Longer Neoadjuvant Chemo
Increasing body mass index and longer neoadjuvant chemotherapy (NAC) are associated with a higher risk of lymphedema in women who undergo axillary lymph node dissection, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 26, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Skipping Surgery in Rectal Cancer: Better or Worse? Skipping Surgery in Rectal Cancer: Better or Worse?
' Unreliable ' assessment of complete clinical response after neoadjuvant chemoradiotherapy for rectal cancer means a watch-and-wait strategy should be followed with caution, suggest results of an expert debate.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 17, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

' Pick the Winner' Trial in Rectal Cancer: Chemoradiation First'Pick the Winner' Trial in Rectal Cancer: Chemoradiation First
A ' pick the winner ' trial found that chemoradiation followed by chemo wins in total neoadjuvant therapy for locally advanced rectal cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 5, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Can T-DM1 Match Chemotherapy Plus Dual Blockade in HER2+ Breast Cancer?
A phase II trial tested docetaxel, trastuzumab, and pertuzumab vs T-DM1 for the neoadjuvant treatment of HER2+ breast cancer. (Source: CancerNetwork)
Source: CancerNetwork - June 14, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Nintedanib Worsens Outcomes Along With Chemo in Advanced Ovarian Cancer
A phase II trial showed that the addition of nintedanib to neoadjuvant chemotherapy did not benefit patients with advanced epithelial ovarian cancer. (Source: CancerNetwork)
Source: CancerNetwork - June 11, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news