Laparoscopic Procedures Provide Better Outcomes in Gastric Cancer

Laparoscopy-assisted distal gastrectomy offered better short-term, post-surgical outcomes for patients with locally advanced gastric cancer who were undergoing neoadjuvant chemotherapy.  
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news

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In patients with locally advanced gastric cancer, laparoscopy-assisted distal gastrectomy (LADG) after neoadjuvant chemotherapy appears to offer more short-term benefits than does open gastrectomy, according to Chinese researchers.Reuters Health Information
Source: Medscape Gastroenterology Headlines - Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news
In this study, an open-label, single cente r, phase 2 randomized clinical trial with a noninferiority design, the authors assessed outcomes at 3 years. All patients received neoadjuvant therapy of oxaliplatin and capecitabine before their operation. Li and colleagues reported significantly lower postoperative complication rates, less postope rative pain, and better adherence to and completion of adjuvant therapy among trial participants.
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
ConclusionsThis study defines 30- and 90-day post-operative outcomes after total gastrectomy in a high-volume center. These outcomes data are critical to the improvement of the informed consent process and as benchmarks for future quality improvement initiatives.
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
Conclusions: The newly developed radiomic signature was a powerful predictor of LN metastasis and the radiomics nomogram could facilitate the preoperative individualized prediction of LN status. Introduction Gastric cancer (GC) is one of the most common malignant tumors and the second leading cause of cancer-related deaths worldwide (1). Accurate evaluation of lymph node metastasis (LNM) status in GC patients is vital for prognosis and treatment decisions (2–4). Some histopathologic factors and biomarkers (e.g., lymphatic invasion, matrix metalloproteinase-2) are found to be able to predict LNM in GC, but mos...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsNeoadjuvant chemotherapy including intraperitoneal paclitaxel followed by sequential intravenous paclitaxel and cisplatin with S ‐1 for resectable advanced gastric cancer is feasible and effective.
Source: Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: RESEARCH ARTICLE Source Type: research
ConclusionLS for adenocarcinoma of the stomach or gastroesophageal junction is feasible and significantly reduces major postoperative morbidity resulting in a reduced length of hospital stay. Therefore, LS should be preferably considered for the curative treatment of patients with these malignancies.
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
Conditions:   Complications, Postoperative;   Surgery--Complications;   Cancer of Stomach;   Chemotherapy Effect Intervention:   Procedure: Laparoscopic D2 distal gastrectomy Sponsors:   West China Hospital;   Beijing Cancer Hospital;   Southern Medical University, China;   Shanghai Zhongshan Hospital;   Chinese PLA General Hospital;   Fujian Medical University Union Hospital;   Ruijin Hospital;   Southwest Hospital, China; &n...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Cancer | Cancer & Oncology | Chemotherapy | Gastrectomy | Gastric (Stomach) Cancer | Gastroenterology | Laparoscopy | Neoadjuvant Chemotherapy Therapy | Neoadjuvant Therapy