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Rethinking neoadjuvant chemotherapy for breast cancer
This BMJ analysis notes that neoadjuvant chemotherapy may not be beneficial to patients as increased pathological response of primary tumour does not translate into a survival benefit. It suggests that the widespread use of neoadjuvant chemotherapy should be reduced. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2018 Category: Consumer Health News Source Type: news

Neoadjuvant Chemotherapy Tied to Better Survival in Advanced Ovarian Cancer Neoadjuvant Chemotherapy Tied to Better Survival in Advanced Ovarian Cancer
The adoption of neoadjuvant chemotherapy is associated with reduced mortality in women with advanced epithelial ovarian cancer, researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 10, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Neoadjuvant Chemotherapy Tied to Improved Ovarian Cancer Survival
In women with advanced ovarian cancer, increased use of neoadjuvant chemotherapy (NACT) followed by surgery — rather than primary cytoreductive surgery — is associated with reduced mortality... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 5, 2018 Category: Primary Care Source Type: news

Adjuvant and Neoadjuvant Therapy for Pancreatic Cancer Adjuvant and Neoadjuvant Therapy for Pancreatic Cancer
Ongoing clinical trials are evaluating aggressive chemotherapy regimens and radiotherapy in pancreatic cancer.Chinese Clinical Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 2, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Contrast-enhanced digital mammography comparable to breast MRI after therapy or chemo
(Mayo Clinic) Contrast-enhanced digital mammography is comparable to breast MRI in evaluating residual breast cancer after neoadjuvant endocrine therapy or chemotherapy, according to the results of a study presented by Mayo Clinic researchers today at the 2017 San Antonio Breast Cancer Symposium. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 6, 2017 Category: Cancer & Oncology Source Type: news

FDA accepts regulatory submission for Lynparza in metastatic breast cancer and grants Priority Review
AstraZeneca and Merck & Co., Inc., (Merck: known as MSD outside the US and Canada) today announced that the US Food and Drug Administration (FDA) has accepted and granted Priority Review for a supplemental New Drug Application (sNDA) for the use of Lynparza (olaparib) tablets in patients with germline BRCA-mutated (gBRCAm), HER2-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant, or metastatic settings. (Source: World Pharma News)
Source: World Pharma News - October 18, 2017 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

AACR: Adding Nivolumab to Neoadjuvant Chemo Slows Resectable NSCLC
Event - free survival prolonged and percentage of patients with a pathological complete response higher with addition of nivolumab (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 12, 2017 Category: Cancer & Oncology Tags: Oncology, Pharmacy, Pulmonology, Conference News, Source Type: news

Chemoradiotherapy Remains Standard of Care in Cervical Cancer Chemoradiotherapy Remains Standard of Care in Cervical Cancer
Chemoradiotherapy remains the standard of care for cervical cancer patients with locally advanced disease, concludes an Indian trial that compared it to neoadjuvant chemotherapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 11, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Study confirms chemoradiation is best treatment for locally advanced cervical cancer
(European Society for Medical Oncology) A 14-year randomized trial in more than 600 patients has concluded that chemoradiation should remain the standard treatment for patients with locally advanced cervical cancer. The findings are reported today at the ESMO 2017 Congress in Madrid. The trial demonstrated no improved disease-free survival with neoadjuvant chemotherapy followed by surgery. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 9, 2017 Category: Cancer & Oncology Source Type: news

CT Abnormality in Patient With Stage II Breast Cancer History
A 57-year-old woman with a history of stage IIB breast cancer (ypT2N1M0) status post neoadjuvant chemotherapy and left partial mastectomy presents to the radiation oncology clinic for CT simulation in preparation for breast radiotherapy. Noncontrast CT scan incidentally found the abnormality depicted with arrows below. (Source: CancerNetwork)
Source: CancerNetwork - September 8, 2017 Category: Cancer & Oncology Authors: Joseph Miccio, MD Tags: Image IQ Source Type: news

Cynvenio and Saint Luke ’s Cancer Institute Launch Pilot Study to...
New Study will use LiquidBiopsy® ClearID® testing and NK Score™ natural killer cell activity testing to monitor breast cancer patients following neoadjuvant chemotherapy.(PRWeb August 17, 2017)Read the full story at http://www.prweb.com/releases/2017/08/prweb14601181.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - August 17, 2017 Category: Pharmaceuticals Source Type: news

Urothelial Cancer Response to Neoadjuvant Chemo Varies by Histologic Variant
Certain histologic variants of urothelial bladder cancer benefit more from neoadjuvant chemotherapy, according to a new study. (Source: CancerNetwork)
Source: CancerNetwork - August 3, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Bladder Cancer Genitourinary Cancers News Source Type: news

Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy
This research article has led to a Practice Changing Update on DynaMed Plus. It concludes that capecitabine adjuvant therapy may improve survival in women with HER2-negative residual invasive breast cancer after neoadjuvant chemotherapy (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 19, 2017 Category: Consumer Health News Source Type: news

Rectal Cancer Response to Preop Tx Doesn't Rule Out Nodal Disease Rectal Cancer Response to Preop Tx Doesn't Rule Out Nodal Disease
Rectal cancer patients who have a complete clinical response (ypT0) to neoadjuvant chemoradiation (NCR) may still have nodal disease, according to new research.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 11, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Chemo Prior to CRT in Nasopharyngeal Carcinoma May Improve Outcomes
The addition of two cycles of neoadjuvant chemotherapy to concurrent chemoradiotherapy improved tumor control in patients with nasopharyngeal carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - June 26, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Head & Neck Cancer News Source Type: news