Advances in myopia control strategies for children
Br J Ophthalmol. 2024 May 22:bjo-2023-323887. doi: 10.1136/bjo-2023-323887. Online ahead of print.ABSTRACTMyopia has long been a global threat to public health. Timely interventions are likely to reduce the risk of vision-threatening complications. There are both established and rapidly evolving therapeutic approaches to slow myopia progression and/or delay its onset. The effective methods for slowing myopia progression include atropine eye-drops, defocus incorporated multiple segments (DIMS) spectacle lenses, spectacle lenses with highly aspherical lenslets target (HALT), diffusion optics technology (DOT) spectacle lenses...
Source: The British Journal of Ophthalmology - May 22, 2024 Category: Opthalmology Authors: Xiu Juan Zhang Ebenezer Zaabaar Amanda Nicole French Fang Yao Tang Ka Wai Kam Clement C Tham Li Jia Chen Chi Pui Pang Jason C Yam Source Type: research
Five-year results of atropine 0.01% efficacy in the myopia control in a European population
Conclusions
Atropine 0.01% is effective in slowing myopia progression in a European population. There were no side effects after 5 years of 0.01% atropine. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Moriche-Carretero, M., Revilla-Amores, R., Gutierrez-Blanco, A., Moreno-Morillo, F. J., Martinez-Perez, C., Sanchez-Tena, M. A., Alvarez-Peregrina, C. Tags: Paediatric ophthalmology Source Type: research
Myopic maculopathy among Chinese children with high myopia and its association with choroidal and retinal changes: the SCALE-HM study
Conclusion
A large proportion of highly myopic Chinese children suffer from myopic maculopathy. Nasal macular ChT may serve as a useful index for classifying and assessing paediatric myopic maculopathy.
Trial registration number
NCT03666052. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Deng, J., Xu, X., Pan, C.-W., Wang, J., He, M., Zhang, B., Yang, J., Hou, X.-W., Zhu, Z., Borchert, G., Chen, J., Cheng, T., Yu, S., Fan, Y., Liu, K., Zou, H., Xu, X., He, X. Tags: Open access Paediatric ophthalmology Source Type: research
Handheld chromatic pupillometry can reliably detect functional glaucomatous damage in eyes with high myopia
Conclusion
PLRs to ramping-up light stimuli are unaltered in highly myopic eyes without other diagnosed ocular conditions. Conversely, HCP can distinguish glaucomatous functional loss in eyes with HM and can be a useful tool to detect/confirm the presence of glaucoma in patients with HM. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Finkelstein, M. T., Nongpiur, M. E., Husain, R., Perera, S., Baskaran, M., Wong, T. T., Aung, T., Milea, D., Najjar, R. P. Tags: Glaucoma Source Type: research
Intravitreal panitumumab and myopic macular degeneration
Conclusions
In this open-labelled, phase-1 study with a mean follow-up of 6.7 months, panitumumab repeatedly administered intravitreally up to a dose of 1.8 mg was not associated with intraocular or systemic adverse effects. During the study period, axial length remained unchanged.
Trial registration number
DRKS00027302. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Bikbov, M. M., Kazakbaeva, G. M., Holz, F. G., Panda-Jonas, S., Gilemzianova, L. I., Khakimov, D. A., Jonas, J. B. Tags: Retina Source Type: research
Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations
Conclusion
Our study identified two population-specific novel loci for AL, expanding our understanding of the genetic basis of AL and providing evidence for a role of the nervous system and glucose metabolism in myopia pathogenesis. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Han, X., Pan, S., Liu, J., Ding, X., Lin, X., Wang, D., Xie, Z., Zeng, C., Liu, F., He, M., Zhou, X., Liu, T., Luo, L., Liu, Y. Tags: Retina Source Type: research
Pseudomyopia as an independent risk factor for myopia onset: a prospective cohort study among school-aged children
Conclusion
This is an important longitudinal study to prove that pseudomyopia is an independent risk factor for myopia development among school-aged children. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Sun, W., Yu, M., Wu, J., Han, X., Jan, C., Song, J., Jiang, W., Xu, Z., Wu, Z., Xu, J., Hu, Y., Bi, H. Tags: Open access Paediatric ophthalmology Source Type: research
Prevalence of myopia among children and adolescents aged 6-16 during COVID-19 pandemic: a large-scale cross-sectional study in Tianjin, China
Conclusions
The prevalence of myopia in Tianjin is high during COVID-19 pandemic. The progression of myopia started to increase dramatically at 8 years, and the increasing slowed down at 14 years. For policy-makers, intervention in the lower age groups may be important to control myopia progression. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Li, T., Wei, R., Du, B., Wu, Q., Yan, J., Meng, X., Liu, Y., Yang, Q., Kee, C.-S., Huang, G., Yan, H. Tags: Open access, COVID-19 Paediatric ophthalmology Source Type: research
Factors influencing myopia stabilisation in young myopic adult Singaporeans
Conclusion
5 in 6 Singaporean young adults had myopia stabilisation. Male gender is 2 times and non-Chinese ethnicities are 2.5 times more likely to achieve myopia stabilisation. However, a proportion of myopes continue to exhibit a clinically significant degree of progression in adulthood. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Foo, L. L., Tan, C.-S., Noel, B., Htoon, H. M., Najjar, R. P., Kathrani, B., Sabanayagam, C., Saw, S.-M. Tags: Editor's choice Epidemiology Source Type: research
Investigation of subclinical ocular inflammation in the aqueous humor of patients with myopia following bilateral sequential collamer lens implantation
CONCLUSION: Following sequential ICL implantation, it appears that a protective response may be activated to mitigate subclinical inflammation in the second eye induced by the initial implantation in the first eye. Additionally, the increase in IOP subsequent to surgery in the first eye may correlate with the presence of inflammatory mediators in the aqueous humor.PMID:38750973 | DOI:10.1016/j.trim.2024.102052 (Source: Transplant Immunology)
Source: Transplant Immunology - May 16, 2024 Category: Transplant Surgery Authors: Xiao-Qin Wang Shi-Jie Zheng Yong-Guo Xiang Fan-Fan Huang Rong-Xi Huang Wen-Juan Wan Ke Hu Source Type: research
Investigation of subclinical ocular inflammation in the aqueous humor of patients with myopia following bilateral sequential collamer lens implantation
CONCLUSION: Following sequential ICL implantation, it appears that a protective response may be activated to mitigate subclinical inflammation in the second eye induced by the initial implantation in the first eye. Additionally, the increase in IOP subsequent to surgery in the first eye may correlate with the presence of inflammatory mediators in the aqueous humor.PMID:38750973 | DOI:10.1016/j.trim.2024.102052 (Source: Transplant Immunology)
Source: Transplant Immunology - May 16, 2024 Category: Transplant Surgery Authors: Xiao-Qin Wang Shi-Jie Zheng Yong-Guo Xiang Fan-Fan Huang Rong-Xi Huang Wen-Juan Wan Ke Hu Source Type: research
Investigation of subclinical ocular inflammation in the aqueous humor of patients with myopia following bilateral sequential collamer lens implantation
CONCLUSION: Following sequential ICL implantation, it appears that a protective response may be activated to mitigate subclinical inflammation in the second eye induced by the initial implantation in the first eye. Additionally, the increase in IOP subsequent to surgery in the first eye may correlate with the presence of inflammatory mediators in the aqueous humor.PMID:38750973 | DOI:10.1016/j.trim.2024.102052 (Source: Transplant Immunology)
Source: Transplant Immunology - May 16, 2024 Category: Transplant Surgery Authors: Xiao-Qin Wang Shi-Jie Zheng Yong-Guo Xiang Fan-Fan Huang Rong-Xi Huang Wen-Juan Wan Ke Hu Source Type: research
Investigation of subclinical ocular inflammation in the aqueous humor of patients with myopia following bilateral sequential collamer lens implantation
CONCLUSION: Following sequential ICL implantation, it appears that a protective response may be activated to mitigate subclinical inflammation in the second eye induced by the initial implantation in the first eye. Additionally, the increase in IOP subsequent to surgery in the first eye may correlate with the presence of inflammatory mediators in the aqueous humor.PMID:38750973 | DOI:10.1016/j.trim.2024.102052 (Source: Transplant Immunology)
Source: Transplant Immunology - May 16, 2024 Category: Transplant Surgery Authors: Xiao-Qin Wang Shi-Jie Zheng Yong-Guo Xiang Fan-Fan Huang Rong-Xi Huang Wen-Juan Wan Ke Hu Source Type: research
Investigation of subclinical ocular inflammation in the aqueous humor of patients with myopia following bilateral sequential collamer lens implantation
CONCLUSION: Following sequential ICL implantation, it appears that a protective response may be activated to mitigate subclinical inflammation in the second eye induced by the initial implantation in the first eye. Additionally, the increase in IOP subsequent to surgery in the first eye may correlate with the presence of inflammatory mediators in the aqueous humor.PMID:38750973 | DOI:10.1016/j.trim.2024.102052 (Source: Transplant Immunology)
Source: Transplant Immunology - May 16, 2024 Category: Transplant Surgery Authors: Xiao-Qin Wang Shi-Jie Zheng Yong-Guo Xiang Fan-Fan Huang Rong-Xi Huang Wen-Juan Wan Ke Hu Source Type: research
Investigation of subclinical ocular inflammation in the aqueous humor of patients with myopia following bilateral sequential collamer lens implantation
CONCLUSION: Following sequential ICL implantation, it appears that a protective response may be activated to mitigate subclinical inflammation in the second eye induced by the initial implantation in the first eye. Additionally, the increase in IOP subsequent to surgery in the first eye may correlate with the presence of inflammatory mediators in the aqueous humor.PMID:38750973 | DOI:10.1016/j.trim.2024.102052 (Source: Transplant Immunology)
Source: Transplant Immunology - May 16, 2024 Category: Transplant Surgery Authors: Xiao-Qin Wang Shi-Jie Zheng Yong-Guo Xiang Fan-Fan Huang Rong-Xi Huang Wen-Juan Wan Ke Hu Source Type: research
