Janssen Presents Updated Data at EHA for Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab cohort of the Phase 1b TriMM-2 study (NCT04108195). Teclistamab, an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA) is being studied in combination with DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 Patients in the study, including a high proportion with prior anti-CD38 exposur...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Presents Updated Results Evaluating First-in-Class GPRC5D Bispecific Antibody Talquetamab in Heavily Pretreated Patients with Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated results from the Phase 1 MonumenTAL-1 first-in-human dose-escalation study of talquetamab (NCT03399799), an investigational, off-the-shelf, T cell redirecting bispecific antibody targeting both GPRC5D, a novel multiple myeloma target, and CD3 on T cells.1 Results from the study showed encouraging responses in heavily pretreated patients with relapsed or refractory multiple myeloma (RRMM) who received talquetamab at the recommended subcutaneous Phase 2 dose (RP2D) administered weekly (QW) or every two weeks (Q2W).2 The...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

The Holocaust and disciplinary myopia in criminology and sociology: social injury as a response to the challenges of legal formalism - Dallier DJ.
Criminological and sociological discourse recognizes the impact of structure on crime, but generally eschews the consideration of structural damage and human suffering emanating from malevolent social movements (e.g., the Holocaust). Legal formalism presen... (Source: SafetyLit)
Source: SafetyLit - June 9, 2022 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Prison Reform Is Undermining Public Health and Safety
For a few months in the fall of 2021, reports of unchecked violence, abuse, and neglect at the jail on New York City’s Rikers Island were plastered across national news before receding back into the routinized cruelty that constitutes the underbelly of American life. This exceptional coverage of the brutality behind bars provoked universal condemnation. But in its short-lived ascent to the forefront of political discussions and popular media, this media “event” failed to account for the most unsettling reality at play: Rikers is everywhere. Last week, while acknowledging that “people are dying&rdquo...
Source: TIME: Health - May 31, 2022 Category: Consumer Health News Authors: Eric Reinhart Tags: Uncategorized freelance healthscienceclimate justice Source Type: news

Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news

When Belle goes looking for Pip
I cannot imagine how cold it is in the seas off the coast of Britain at this time of year, but lots of people swim year round and my dog Belle (aka The Beeble) is no exception. Give her a beach with an easy access into the water and she’s off, ears flying as she throws herself into the waves. This is pretty prosaic as pictures go, a dog in the water. But what could you do with it to make it more surreal or alternative? Is there anything you can’t see in the picture that suggests a bigger story? You can see my effort here: Belle flies out of the waves barking madly. Ears flying in all directions. She shakes all ...
Source: The Hysterectomy Association - May 12, 2022 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Creative Writing writing prompt Source Type: news

Experts Can ’t Agree on How Much Screen Time Is Too Much for Adults
The COVID-19 pandemic shifted our lives in myriad ways, including the amount of time we spent glued to our devices. Research published in 2021 found that Americans in their early twenties used their phones an average of 28.5 hours per week in 2020—up from 25.9 hours per week in 2018. One review of studies conducted in 2020 and 2021 put the estimates even higher, finding that average screen time for adults in the U.S. and other countries increased 60–80% from before the pandemic. Excessive screen time has been shown to have negative effects on children and adolescents. It’s been linked to psychological pr...
Source: TIME: Health - May 9, 2022 Category: Consumer Health News Authors: Jamie Friedlander Serrano Tags: Uncategorized healthscienceclimate Mental Health Source Type: news

Contrast-Reducing Spectacles Could Slow Myopia Contrast-Reducing Spectacles Could Slow Myopia
Spectacles that reduce retinal contrast could slow the progression of myopia.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - May 4, 2022 Category: Allergy & Immunology Tags: Ophthalmology News Source Type: news

What's Better: Residual Hyperopia or Residual Myopia? What's Better: Residual Hyperopia or Residual Myopia?
Dr Garg discusses a paper from Dr Steven Schallhorn and colleagues on the effect of residual astigmatism on uncorrected visual acuity and patient satisfaction.Medscape Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 11, 2022 Category: Consumer Health News Tags: Ophthalmology Viewpoint Source Type: news

To End COVID-19, We Have to Admit That We ’ve Failed
In 1985, the first HIV vaccine trial was launched with great fanfare. The previous year, Margaret Heckler, the U.S. Secretary of Health and Human Services, confidently declared that an HIV vaccine would be created within two years. But almost four decades after the initial discovery of the HIV virus, there is still no viable HIV/AIDS vaccine. That doesn’t mean, though, that there is no cure. The grueling and largely thankless work of trialing an HIV/AIDS vaccine has continued steadily over the past four decades (the most recent one launched in January 2022, using Moderna’s mRNA technology), making it the longes...
Source: TIME: Health - March 16, 2022 Category: Consumer Health News Authors: Dan Werb Tags: Uncategorized COVID-19 Source Type: news

The red light that could stop short sight getting worse
Researchers found that spending just six minutes a day looking into a binocular-like device that emits a special red light slowed the progression of myopia by almost 70 per cent. (Source: the Mail online | Health)
Source: the Mail online | Health - March 1, 2022 Category: Consumer Health News Source Type: news

Vaccine scientists have been chasing variants. Now, they’re seeking a universal coronavirus vaccine.
To many scientists, developing variant-specific vaccines is a short-term, shortsighted and unsustainable strategy. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - February 14, 2022 Category: Consumer Health News Authors: Carolyn Y. Johnson Source Type: news

Myopia Progressed Faster in Children Under COVID-19 Lockdowns
FRIDAY, Jan. 21, 2022 -- Myopia progressed more rapidly in schoolchildren exposed to more COVID-19-related lockdown measures, according to a study published online Jan. 14 in JAMA Network Open. Kai Yip Choi, Ph.D., from the Hong Kong Polytechnic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 21, 2022 Category: Pharmaceuticals Source Type: news

Specialized Spectacles Slow Myopia During Lockdown Specialized Spectacles Slow Myopia During Lockdown
Spectacles designed to slow the progression of myopia appear to work even during a COVID-19 lockdown.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 18, 2022 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Myopia Progression May Continue in Young Adults Into Late 20s
WEDNESDAY, Jan. 12, 2022 -- Myopia progression may continue for more than one-third of young adults during the third decade of life, according to a study published online Jan. 6 in JAMA Ophthalmology. Samantha Sze-Yee Lee, Ph.D., from the Lions Eye... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 12, 2022 Category: Pharmaceuticals Source Type: news