The response of retinal ganglion cells to optical defocused visual stimuli in mouse retinas
This study aimed to investigate the response characteristics of Retinal Ganglion Cells (RGCs), represented by alpha (α) RGCs, when exposed to focused, simulated defocused pattern images and astigmatically defocused images projected onto mouse retinas. Negative pressure was applied to stretch the soma of RGC in vitro to simulate myopia using a 7-8 μm diameter glass microelectrode, resulting in a 5% increase in the cell's diameter. A custom-made device was utilized to project spherically (equal to ±10 and ± 20 D) and astigmatically (+6.00D) defocused images onto the retinas. As a control for a deficient intact retinal ci...
Source: Experimental Eye Research - February 21, 2024 Category: Opthalmology Authors: Chunghim So Ting Zhang Qin Wang ChunTing Qiu Lestrange-Anginieur Elie de Feng Pan Source Type: research

Pediatric myopic strabismus fixus: clinical features and surgical outcomes of silicone band loop myopexy
CONCLUSION: The clinical profile of MSF in children is almost similar to adults. This condition is a rare entity among adults as well as children. Majority of children with MSF presented with esotropia-hypotropia complex. Silicone band loop myopexy with or without medial rectus recession proves to be a reliable surgical procedure as it provides stable outcomes in terms of ocular alignment and motility among children.PMID:38380479 | DOI:10.1080/09273972.2024.2306348 (Source: Strabismus)
Source: Strabismus - February 21, 2024 Category: Research Authors: Sakshi Lalwani Virender Sachdeva Ramesh Kekunnaya Source Type: research

The response of retinal ganglion cells to optical defocused visual stimuli in mouse retinas
This study aimed to investigate the response characteristics of Retinal Ganglion Cells (RGCs), represented by alpha (α) RGCs, when exposed to focused, simulated defocused pattern images and astigmatically defocused images projected onto mouse retinas. Negative pressure was applied to stretch the soma of RGC in vitro to simulate myopia using a 7-8 μm diameter glass microelectrode, resulting in a 5% increase in the cell's diameter. A custom-made device was utilized to project spherically (equal to ±10 and ± 20 D) and astigmatically (+6.00D) defocused images onto the retinas. As a control for a deficient intact retinal ci...
Source: Experimental Eye Research - February 21, 2024 Category: Opthalmology Authors: Chunghim So Ting Zhang Qin Wang ChunTing Qiu Lestrange-Anginieur Elie de Feng Pan Source Type: research

Pediatric myopic strabismus fixus: clinical features and surgical outcomes of silicone band loop myopexy
CONCLUSION: The clinical profile of MSF in children is almost similar to adults. This condition is a rare entity among adults as well as children. Majority of children with MSF presented with esotropia-hypotropia complex. Silicone band loop myopexy with or without medial rectus recession proves to be a reliable surgical procedure as it provides stable outcomes in terms of ocular alignment and motility among children.PMID:38380479 | DOI:10.1080/09273972.2024.2306348 (Source: Strabismus)
Source: Strabismus - February 21, 2024 Category: Research Authors: Sakshi Lalwani Virender Sachdeva Ramesh Kekunnaya Source Type: research