Interleukin 35 (IL-35) and IL-35-producing Regulatory B Cells (i35-Bregs): Critical Regulators of Autoimmune Diseases.
Immunology Interest Group Charles E. Egwuagu is Chief of the Molecular Immunology Section, National Eye Institute (NEI), NIH. He received his Ph.D in Epidemiology and Microbiology from Yale University Graduate School and a Master of Public Health (M.P.H) degree in Infectious Disease Epidemiology from Yale School of Medicine, New Haven, Connecticut. Dr. Egwuagu did a 2-year Post-doctoral Fellowship in Molecular Immunology at NEI/NIH and then served as a Commissioned Officer of the United States Public Health Service (PHS) for 10 years, attaining the rank of Captain (06). Research in the Egwuagu laboratory is on autoreacti...
Source: Videocast - All Events - February 18, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Microbiology and Infectious Diseases Subcommittee - January 2016
Report from Division Director and Division Staff Air date: 1/25/2016 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 12, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Modulation of T Cell Signaling by ITK.
Immunology Interest Group Leslie Berg is a Professor in the Department of Pathology at the University of Massachusetts and the Director of graduate program in Microbiology and Immunology, who is well known for her key studies in T lymphocyte signaling. While a postdoctoral fellow with Mark Davis, she generated the first Class II-specific TCR transgenic mice and used them for seminal studies on thymic selection. As an Assistant Professor, she cloned out a series of tyrosine kinases expressed in T cells including Jak3 and Itk. Through the generation and study of gene-targeted mice that lack these ki...
Source: Videocast - All Events - January 7, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Functional dynamics of the gut microbiome in health and disease
Presented by: Claire Fraser, Ph.D., Professor of Medicine, Microbiology and Immunology; Director, Institute for Genome Sciences; University of Maryland School of MedicineCategory: WALS - Wednesday Afternoon LecturesAired date: 10/27/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - October 28, 2015 Category: Journals (General) Tags: Past Events Source Type: video

WHIM Syndrome Immunodeficiency: the Trail from Tail to Tale
Immunology Interest Group Dr. Murphy is an authority on immunoregulation by chemokines and related leukocyte chemoattractants. His basic research discoveries include the first leukocyte chemoattractant receptors, including the HIV coreceptor CCR5; the HIV restriction factor CCR5D32; the first virally encoded chemokine receptors; and the role of CCR5 in West Nile virus pathogenesis. Dr. Murphy has received numerous patents and awards, including the NIAID Mentor of the Year Award, the NIH Director’s Award (twice), the Pillars of Immunology Award from the Journal of Immunology, and both the Dolph Adams Award and Marie Bonaz...
Source: Videocast - All Events - October 13, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Interfering with Interferons for Host Targeted Therapy of Bacterial Infections
Presented by: Laurel L. Lenz, Ph.D., Professor of Immunology & Microbiology, University of Colorado School of Medicine Category: ImmunologyAired date: 10/07/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - October 8, 2015 Category: Journals (General) Tags: Past Events Source Type: video

Division of Microbiology and Infectious Diseases Subcommittee - September 2015
Presented by: NIAID, NIHCategory: National Institute of Allergy and Infectious DiseasesAired date: 09/21/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - September 29, 2015 Category: Journals (General) Tags: Past Events Source Type: video

Interfering with Interferons for Host Targeted Therapy of Bacterial Infections.
Laurel Lenz has made major contributions to our understanding of the innate and adaptive immune response to the intracellular bacterial pathogen Listeria monocytogenes. As a Ph.D. student with Mike Bevan at the University of Washington Laurel performed pioneering work on the requirements for CD8+ antigen presentation by Listeria identifying a role for the non-classical restriction element H-2-M3. Later as a postdoctoral fellow in the lab of Dan Portnoy at UC Berkeley he delved into the cell biology of the Listeria-macrophage interaction discovering a new secretory element SecA2 that influences both virulence and the induc...
Source: Videocast - All Events - September 28, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Division of Microbiology and Infectious Diseases Subcommittee - September 2015
Report from Division Director and Division StaffAir date: 9/21/2015 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 16, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Division of Microbiology and Infectious Diseases Subcommittee - May 2015
Presented by: NIAID, NIHCategory: National Institute of Allergy and Infectious DiseasesAired date: 05/18/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - May 21, 2015 Category: Journals (General) Tags: Past Events Source Type: video

Thymocyte: stromal cell crosstalk governing normal and neoplastic T cell development
Presented by: Lauren Ehrlich, Ph.D., Tenure-Track Faculty, Molecular Genetics & Microbiology, University of Texas at AustinCategory: ImmunologyAired date: 05/20/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - May 21, 2015 Category: Journals (General) Tags: Past Events Source Type: video

Division of Microbiology and Infectious Diseases Subcommittee - May 2015
Report from Division Director and Division StaffAir date: 5/18/2015 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 7, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

The mammalian virome in genetic analysis of health and disease pathogenesis
Presented by: Herbert W. 'Skip' Virgin IV, M.D., Ph.D., Edward Mallinckrodt Professor and Chair Department of Pathology and Immunology, Professor of Molecular Microbiology, and Professor of Medicine at Washington University School of MedicineCategory: WALS - Wednesday Afternoon LecturesAired date: 04/22/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - April 27, 2015 Category: Journals (General) Tags: Past Events Source Type: video

CRISPR-Cas genome surveillance: From basic biology to transformative technology
Wednesday Afternoon Lecture Series Margaret Pittman Lecture Dr. Doudna, who specializes in the study of RNA, will present a brief history of the bacterial RNA-guided CRISPR biology from its initial discovery through the elucidation of the CRISPR-Cas9 enzyme mechanism. Using CRISPR-Cas (clustered regularly interspaced short palindromic repeats) technology provides the foundation for remarkable developments in modifying, regulating, or marking genomic loci in a wide variety of cells and organisms. These results highlight a new era in which genomic manipulation is no longer a bottleneck to experiments, paving the way to fun...
Source: Videocast - All Events - March 9, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Anti-viral resident memory CD8 T cells
Immunology Interest Group Dr. David Masopust is the front-runner in our race to understand T cell memory formation and maintenance. His break-through studies on migration and effector function of memory CD8 T cells have re-shaped the field, and his current work on viral and bacterial vaccines that target tissue resident T cells has opened up new avenues in cellular immunology. Dave’s fascination with T cell memory started with his PhD work in Leo Lefrancois’ lab at U. Conn, where he studied the migration and tissue distribution of memory cells. It was his pioneering work during that time that resulted in the landmar...
Source: Videocast - All Events - March 5, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video