Microencapsulated Benzoyl Peroxide for Rosacea in Context: A Review of the Current Treatment Landscape
AbstractRosacea, a chronic skin condition affecting millions of people in the USA, leads to significant social and professional stigmatization. Effective management strategies are crucial to alleviate symptoms and improve patients ’ quality of life. Encapsulated benzoyl peroxide 5% (E-BPO 5%) is a newly FDA-approved topical treatment for rosacea that shows promise in enhancing therapeutic response and minimizing skin irritation. This review aims to assess the role of recently FDA approved E-BPO 5% in the current treatment l andscape for rosacea management, as it is not yet included in clinical guidelines that predominant...
Source: Drugs - February 29, 2024 Category: Drugs & Pharmacology Source Type: research

Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults —Reply
In Reply Noting the differences in anerobic coverage between cefepime and piperacillin-tazobactam, Dr Chanderraj and colleagues inquire how commonly clinicians in our recent ACORN trial elected to co-administer antibiotics with anerobic coverage (eg, metronidazole or clindamycin) to patients in the cefepime group vs the piperacillin-tazobactam group. In the 14 days after enrollment, 564 patients (46.5%) in the cefepime group and 248 patients (19.1%) in the piperacillin-tazobactam group received either metronidazole or clindamycin, of which 535 (44.1%) and 173 (13.3%), respectively, received them during the first 3 days aft...
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research

The Impact of Mechanical Bowel Preparation and Oral Antibiotics in Colorectal Cancer Surgery (MECCA Study): A Prospective Randomized Clinical Trial
Conclusions: Preoperative antibiotic therapy in combination with mechanical bowel preparation seemed to be correlated with a lower SSI rate after colorectal cancer surgery.PMID:38398474 | DOI:10.3390/jcm13041162 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - February 24, 2024 Category: Cancer & Oncology Authors: Maximos Frountzas Victoria Michalopoulou Georgia Georgiou Despoina Kanata Maria Matiatou Despina Kimpizi Georgia Matthaiou Spilios Spiliotopoulos Dimitrios Vouros Konstantinos G Toutouzas George E Theodoropoulos Source Type: research

The Impact of Mechanical Bowel Preparation and Oral Antibiotics in Colorectal Cancer Surgery (MECCA Study): A Prospective Randomized Clinical Trial
Conclusions: Preoperative antibiotic therapy in combination with mechanical bowel preparation seemed to be correlated with a lower SSI rate after colorectal cancer surgery.PMID:38398474 | PMC:PMC10889669 | DOI:10.3390/jcm13041162 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - February 24, 2024 Category: Cancer & Oncology Authors: Maximos Frountzas Victoria Michalopoulou Georgia Georgiou Despoina Kanata Maria Matiatou Despina Kimpizi Georgia Matthaiou Spilios Spiliotopoulos Dimitrios Vouros Konstantinos G Toutouzas George E Theodoropoulos Source Type: research

The Impact of Mechanical Bowel Preparation and Oral Antibiotics in Colorectal Cancer Surgery (MECCA Study): A Prospective Randomized Clinical Trial
Conclusions: Preoperative antibiotic therapy in combination with mechanical bowel preparation seemed to be correlated with a lower SSI rate after colorectal cancer surgery.PMID:38398474 | PMC:PMC10889669 | DOI:10.3390/jcm13041162 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - February 24, 2024 Category: Cancer & Oncology Authors: Maximos Frountzas Victoria Michalopoulou Georgia Georgiou Despoina Kanata Maria Matiatou Despina Kimpizi Georgia Matthaiou Spilios Spiliotopoulos Dimitrios Vouros Konstantinos G Toutouzas George E Theodoropoulos Source Type: research

Effects of Preoperative Quadruple Therapy for Helicobacter pylori on Bariatric Surgery Metabolic Outcomes
ConclusionsPreoperative treatment with OCAM has been associated to poorer glycemic and weight loss outcomes after BS. More research is needed on the influence of OCAM on gut microbiota, and in turn, the effect of the latter on metabolic and weight loss outcomes after BS.Graphical Abstract (Source: Obesity Surgery)
Source: Obesity Surgery - February 24, 2024 Category: Surgery Source Type: research