Prognostic significance of tumour budding in Merkel cell carcinoma
Pol J Pathol. 2023;74(2):144-147. doi: 10.5114/pjp.2023.129404.ABSTRACTPrognostic factors in Merkel cell carcinoma (MCC) are scarce. Tumour budding (TB) has been shown to have a prognostic role in different cancers but has not been explored in MCC. We aimed to determine if TB influences survival in MCC. We performed a retrospective evaluation of 45 cases of MCC in a cancer centre. This included a survival analysis involving TB in patients with MCC, and we searched for variables associated with TB. The mean age of the patients was 69 years. Histologically, the average Breslow was 11.36 mm, and the mean mitotic rate was 31.9...
Source: Polish Journal of Pathology - September 20, 2023 Category: Pathology Authors: Leslye A Alvarez-Coronel Luisa F Rivera-Moncada Leonardo Saul Lino-Silva Source Type: research
Targeted therapy and immunotherapy for orbital and periorbital tumors: a major review
This article will focus on recent updates in the application of available targeted and immunotherapy for managing orbital and periorbital tumors and tumor-like conditions, which include cutaneous basal cell carcinoma, cutaneous squamous cell carcinoma, cutaneous melanoma, Merkel cell carcinoma, sebaceous gland carcinoma, solitary fibrous tumor, dermatofibrosarcoma protuberans, orbital meningioma, neurofibromatosis, Langerhans cell histiocytosis, ocular adnexal lymphoma, orbital lymphatic malformation, and adenoid cystic carcinoma.PMID:37728602 | DOI:10.1080/01676830.2023.2256848 (Source: Orbit)
Source: Orbit - September 20, 2023 Category: Opthalmology Authors: Emmanuel Lee Boniao Richard C Allen Gangadhara Sundar Source Type: research
Prognostic significance of tumour budding in Merkel cell carcinoma
Pol J Pathol. 2023;74(2):144-147. doi: 10.5114/pjp.2023.129404.ABSTRACTPrognostic factors in Merkel cell carcinoma (MCC) are scarce. Tumour budding (TB) has been shown to have a prognostic role in different cancers but has not been explored in MCC. We aimed to determine if TB influences survival in MCC. We performed a retrospective evaluation of 45 cases of MCC in a cancer centre. This included a survival analysis involving TB in patients with MCC, and we searched for variables associated with TB. The mean age of the patients was 69 years. Histologically, the average Breslow was 11.36 mm, and the mean mitotic rate was 31.9...
Source: Polish Journal of Pathology - September 20, 2023 Category: Pathology Authors: Leslye A Alvarez-Coronel Luisa F Rivera-Moncada Leonardo Saul Lino-Silva Source Type: research
Targeted therapy and immunotherapy for orbital and periorbital tumors: a major review
This article will focus on recent updates in the application of available targeted and immunotherapy for managing orbital and periorbital tumors and tumor-like conditions, which include cutaneous basal cell carcinoma, cutaneous squamous cell carcinoma, cutaneous melanoma, Merkel cell carcinoma, sebaceous gland carcinoma, solitary fibrous tumor, dermatofibrosarcoma protuberans, orbital meningioma, neurofibromatosis, Langerhans cell histiocytosis, ocular adnexal lymphoma, orbital lymphatic malformation, and adenoid cystic carcinoma.PMID:37728602 | DOI:10.1080/01676830.2023.2256848 (Source: Orbit)
Source: Orbit - September 20, 2023 Category: Opthalmology Authors: Emmanuel Lee Boniao Richard C Allen Gangadhara Sundar Source Type: research
Prognostic significance of tumour budding in Merkel cell carcinoma
Pol J Pathol. 2023;74(2):144-147. doi: 10.5114/pjp.2023.129404.ABSTRACTPrognostic factors in Merkel cell carcinoma (MCC) are scarce. Tumour budding (TB) has been shown to have a prognostic role in different cancers but has not been explored in MCC. We aimed to determine if TB influences survival in MCC. We performed a retrospective evaluation of 45 cases of MCC in a cancer centre. This included a survival analysis involving TB in patients with MCC, and we searched for variables associated with TB. The mean age of the patients was 69 years. Histologically, the average Breslow was 11.36 mm, and the mean mitotic rate was 31.9...
Source: Polish Journal of Pathology - September 20, 2023 Category: Pathology Authors: Leslye A Alvarez-Coronel Luisa F Rivera-Moncada Leonardo Saul Lino-Silva Source Type: research
