Comparative Genitourinary Safety of In-class Sodium-Glucose Cotransporter-2 Inhibitors among Patients with Heart Failure with Preserved Ejection Fraction: A Cohort Study
ConclusionsThere was no significant difference in the risk of UTI or genital infection among patients with HFpEF who initiated canagliflozin, dapagliflozin, or empagliflozin. (Source: American Journal of Cardiovascular Drugs)
Source: American Journal of Cardiovascular Drugs - April 30, 2024 Category: Cardiology Source Type: research
Estimated Medicare Part D Savings From Generic Drugs With a Skinny Label
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M23-3212. Online ahead of print.NO ABSTRACTPMID:38684101 | DOI:10.7326/M23-3212 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Alexander C Egilman Aaron S Kesselheim Ameet Sarpatwari Benjamin N Rome Source Type: research
Medicare Negotiation's Drug Reformulation Problem
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M24-0138. Online ahead of print.NO ABSTRACTPMID:38684103 | DOI:10.7326/M24-0138 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Matthew Vogel Benjamin N Rome Aaron S Kesselheim William B Feldman Source Type: research
Medicare Negotiation's Drug Reformulation Problem
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M24-0138. Online ahead of print.NO ABSTRACTPMID:38684103 | DOI:10.7326/M24-0138 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Matthew Vogel Benjamin N Rome Aaron S Kesselheim William B Feldman Source Type: research
Estimated Medicare Part D Savings From Generic Drugs With a Skinny Label
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M23-3212. Online ahead of print.NO ABSTRACTPMID:38684101 | DOI:10.7326/M23-3212 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Alexander C Egilman Aaron S Kesselheim Ameet Sarpatwari Benjamin N Rome Source Type: research
The Removal of Total Knee Arthroplasty From the Inpatient-Only List has Improved Patient Optimization
CONCLUSION: Outpatient TKA has increased considerably post-IPO removal. As this regulatory change has allowed older patients with increased comorbidities to undergo oTKA, the need for appropriate preoperative optimization has increased. The current data set demonstrates that surgeons have improved preoperative optimization efforts for select modifiable risk factors.PMID:38684134 | DOI:10.5435/JAAOS-D-22-01132 (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - April 29, 2024 Category: Orthopaedics Authors: Niall H Cochrane Billy I Kim William A Jiranek Thorsten M Seyler Michael P Bolognesi Sean P Ryan Source Type: research
The Role of Delirium on Short- and Long-Term Postoperative Outcomes Following Major Gastrointestinal Surgery for Cancer
CONCLUSIONS: Postoperative delirium occurred in one in 50 patients undergoing surgical resection of a digestive tract cancer. Delirium was linked to a reduced likelihood of achieving an optimal postoperative outcome, increased ICU utilization, higher expenditures, and a worse long-term prognosis. Initiatives to prevent delirium are vital to improve postoperative outcomes among cancer surgery patients.PMID:38683304 | DOI:10.1245/s10434-024-15358-x (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Erryk S Katayama Hunter Stecko Selamawit Woldesenbet Mujtaba Khalil Muhammad Musaab Munir Yutaka Endo Diamantis Tsilimigras Timothy M Pawlik Source Type: research
Comparison of Comorbidity Models Within a Population-Based Cohort of Older Adults With Non-Hodgkin Lymphoma
CONCLUSION: The optimal measure of comorbidity in NHL is unknown. Here, we demonstrate that the three-category TRES and five-category NHL-5 scores perform as well as the 14-16 category CCI and NCI scores in terms of association with OS and lymphoma-specific survival. These simple scores could be more easily used in clinical practice without prognostic loss.PMID:38684043 | DOI:10.1200/CCI.23.00223 (Source: Clinical Lymphoma and Myeloma)
Source: Clinical Lymphoma and Myeloma - April 29, 2024 Category: Cancer & Oncology Authors: Max J Gordon Zhigang Duan Hui Zhao Loretta Nastoupil Swaminathan Iyer Alessandra Ferrajoli Alexey V Danilov Sharon H Giordano Source Type: research
The Role of Delirium on Short- and Long-Term Postoperative Outcomes Following Major Gastrointestinal Surgery for Cancer
CONCLUSIONS: Postoperative delirium occurred in one in 50 patients undergoing surgical resection of a digestive tract cancer. Delirium was linked to a reduced likelihood of achieving an optimal postoperative outcome, increased ICU utilization, higher expenditures, and a worse long-term prognosis. Initiatives to prevent delirium are vital to improve postoperative outcomes among cancer surgery patients.PMID:38683304 | DOI:10.1245/s10434-024-15358-x (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Erryk S Katayama Hunter Stecko Selamawit Woldesenbet Mujtaba Khalil Muhammad Musaab Munir Yutaka Endo Diamantis Tsilimigras Timothy M Pawlik Source Type: research
Comparison of Comorbidity Models Within a Population-Based Cohort of Older Adults With Non-Hodgkin Lymphoma
CONCLUSION: The optimal measure of comorbidity in NHL is unknown. Here, we demonstrate that the three-category TRES and five-category NHL-5 scores perform as well as the 14-16 category CCI and NCI scores in terms of association with OS and lymphoma-specific survival. These simple scores could be more easily used in clinical practice without prognostic loss.PMID:38684043 | DOI:10.1200/CCI.23.00223 (Source: Clinical Lymphoma and Myeloma)
Source: Clinical Lymphoma and Myeloma - April 29, 2024 Category: Cancer & Oncology Authors: Max J Gordon Zhigang Duan Hui Zhao Loretta Nastoupil Swaminathan Iyer Alessandra Ferrajoli Alexey V Danilov Sharon H Giordano Source Type: research
The Removal of Total Knee Arthroplasty From the Inpatient-Only List has Improved Patient Optimization
CONCLUSION: Outpatient TKA has increased considerably post-IPO removal. As this regulatory change has allowed older patients with increased comorbidities to undergo oTKA, the need for appropriate preoperative optimization has increased. The current data set demonstrates that surgeons have improved preoperative optimization efforts for select modifiable risk factors.PMID:38684134 | DOI:10.5435/JAAOS-D-22-01132 (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - April 29, 2024 Category: Orthopaedics Authors: Niall H Cochrane Billy I Kim William A Jiranek Thorsten M Seyler Michael P Bolognesi Sean P Ryan Source Type: research
Medicare Negotiation's Drug Reformulation Problem
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M24-0138. Online ahead of print.NO ABSTRACTPMID:38684103 | DOI:10.7326/M24-0138 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Matthew Vogel Benjamin N Rome Aaron S Kesselheim William B Feldman Source Type: research
Estimated Medicare Part D Savings From Generic Drugs With a Skinny Label
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M23-3212. Online ahead of print.NO ABSTRACTPMID:38684101 | DOI:10.7326/M23-3212 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Alexander C Egilman Aaron S Kesselheim Ameet Sarpatwari Benjamin N Rome Source Type: research
The Role of Delirium on Short- and Long-Term Postoperative Outcomes Following Major Gastrointestinal Surgery for Cancer
CONCLUSIONS: Postoperative delirium occurred in one in 50 patients undergoing surgical resection of a digestive tract cancer. Delirium was linked to a reduced likelihood of achieving an optimal postoperative outcome, increased ICU utilization, higher expenditures, and a worse long-term prognosis. Initiatives to prevent delirium are vital to improve postoperative outcomes among cancer surgery patients.PMID:38683304 | DOI:10.1245/s10434-024-15358-x (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Erryk S Katayama Hunter Stecko Selamawit Woldesenbet Mujtaba Khalil Muhammad Musaab Munir Yutaka Endo Diamantis Tsilimigras Timothy M Pawlik Source Type: research
Surgical versus Transcatheter Aortic Valve Replacement in Low Risk Medicare Beneficiaries
Recent approval of transcatheter aortic valve replacement (TAVR) in patients at low surgical risk has resulted in a rapid real-world expansion of TAVR in patients not otherwise examined in recent low-risk trials. We sought to evaluate the outcomes of surgical aortic valve replacement (SAVR) vs TAVR in low-risk Medicare beneficiaries. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 28, 2024 Category: Cardiovascular & Thoracic Surgery Authors: J Hunter Mehaffey, Mohammad Kawsara, Vikrant Jagadeesan, J.W. Hayanga, Dhaval Chauhan, Lawrence Wei, Christopher Mascio, J Scott Rankin, Ramesh Daggubati, Vinay Badhwar Source Type: research
