Efficacy and Safety of Transitioning to Lemborexant from Z-drug, Suvorexant, and Ramelteon in Japanese Insomnia Patients: An Open-label, Multicenter Study
ConclusionsDirect transition to LEM may be a valid treatment option for patients with insomnia who are dissatisfied with current treatment.Trial RegistrationClinicalTrials.gov identifier, NCT04742699. (Source: Advances in Therapy)
Source: Advances in Therapy - March 9, 2024 Category: Drugs & Pharmacology Source Type: research

Efficacy and safety of eszopiclone combined with drug therapy in the treatment of insomnia after stroke: A network meta-analysis and systematic review
ConclusionMulti-drug therapy based on eszopiclone can effectively improve the sleep quality of patients with insomnia after stroke, and ESZ+SDOL has significant efficacy and safety. However, due to the limitations of this study, efficacy ranking cannot fully explain the superiority or inferiority of clinical efficacy. In the future, more multicentre, large sample, double-blind randomized controlled trials are needed to supplement and demonstrate the results of this study. (Source: PLoS One)
Source: PLoS One - February 5, 2024 Category: Biomedical Science Authors: Ruo-Yang Li Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial
CONCLUSION: The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.PMID:38213251 | PMC:PMC10774717 | DOI:10.19852/j.cnki.jtcm.2024.01.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - January 12, 2024 Category: Complementary Medicine Authors: Wang Yichen W U Shiyi Wang Zhengyan Chang Wenling Xie Zhihao Tang Xing Zhao Songmei Zhou Jing Chen Zehong Wang Chao Yang Chunxia Source Type: research