Orexin dual receptor antagonists, zolpidem, zopiclone, eszopiclone, and cognitive research: A comprehensive dose-response meta-analysis
ConclusionWe recommend DORA as the best intervention for insomnia because it is highly effective in inducing and maintaining sleep without impairing cognition. Although zolpidem has a more pronounced effect on maintaining sleep, it is best to reduce its use because of its side effects. Eszopiclone and zopiclone improved sleep quality, but their safety in cognition remains to be verified. (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - January 9, 2023 Category: Neuroscience Source Type: research
Network meta-analysis comparing the effectiveness of a prescription digital therapeutic for chronic insomnia to medications and face-to-face cognitive behavioral therapy in adults
CONCLUSIONS: This network meta-analysis demonstrated that a PDT delivering CBT-I had the highest probability of being most effective compared to face-to-face CBT-I, prescription sleep medications, or placebo, as measured by reductions in mean ISI score from baseline and ISI-determined remittance.* Somryst is the registered trademark for a prescription digital therapeutics for insomnia developed by Pear Therapeutics (US), Inc.PMID:35938209 | DOI:10.1080/03007995.2022.2108616 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - August 8, 2022 Category: Research Authors: Felicia Forma Ramya Pratiwadi Fadoua El-Moustaid Nathaniel Smith Frances Thorndike Fulton Velez Source Type: research
