Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants
Conditions: Healthy; Hepatic Insufficiency Interventions: Drug: Pirtobrutinib Sponsors: Eli Lilly and Company; Loxo Oncology, Inc. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials

New Published Data Demonstrates Correlation Between Itch Cytokine Interleukin-31 Reduction and Pruritis Improvement in Primary Biliary Cholangitis in Phase 3 Post-Hoc Analysis of CymaBay's Seladelpar
NEWARK, Calif., Jan. 3, 2024 /PRNewswire/ -- CymaBay Therapeutics, Inc. (NASDAQ: CBAY), a biopharmaceutical company focused on innovative therapies for patients with liver and other chronic diseases, today announced the first published findings... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - January 3, 2024 Category: Pharmaceuticals Source Type: clinical trials

A Phase IV Study of Huazhi Rougan Granule
Conditions: A Phase IV Trial to Investigate the Efficacy and Safety of Huazhi Rougan Granule in the Treatment of Non-alcoholic Simple Fatty Liver Interventions: Drug: Huazhi Rougan Granule Placebo granule Sponsors: Shandong New Time Pharmaceutical Co., LTD Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

Impact of Skeletal Muscle Quality and Loss on the Outcome of Liver Transplantation
Conditions: Liver Transplantation; Muscle Loss; Muscle Quality Sponsors: Zhejiang University; First Affiliated Hospital of Zhejiang University; Shulan (Hangzhou) Hospital; The Affiliated Hospital of Qingdao University; West China Hospital; Huashan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

Plasma Exchange for Amanita Toxin-induced Acute Liver Failure
Conditions: Acute Liver Failure Interventions: Device: Therapeutic Plasma Exchange (PEX) Sponsors: Hannover Medical School Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 2, 2024 Category: Research Source Type: clinical trials

Effect of Therapeutic Plasma Exchange on Liver Transplantation-free Survival in Amanita Toxin-induced Acute Liver Failure - a Multicenter Retrospective Study Over 10 Years
Conditions: Acute Liver Failure Interventions: Device: Therapeutic Plasma Exchange (PEX) Sponsors: Hannover Medical School Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials

COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases
Conditions: Colorectal Cancer; Liver Metastases; Liver Metastasis Colon Cancer; Unresectable Solid Tumor Interventions: Procedure: Irreversible electroporation; Radiation: Stereotactic body radiotherapy Sponsors: Amsterdam UMC, location VUmc; Angiodynamics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials

CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules
Conditions: HCC; Hepatocellular Carcinoma Interventions: Diagnostic Test: CEUS vs aMRI Sponsors: University of Texas Southwestern Medical Center; University of Michigan Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials

Population-wide Research for HBV-related Liver Diseases in Maoming City
Conditions: HBV Infection; Chronic Hepatitis B; Cirrhosis; HCC Interventions: Other: Rapid tests for HBsAg Sponsors: Nanfang Hospital, Southern Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials

Prospective, Multicenter Clinical Study of Prolonged-release Tacrolimus in Stable Pediatric Liver Transplant Recipients
Conditions: Liver Transplant Interventions: Drug: Tacrolimus Sustained-release Capsules Sponsors: RenJi Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials

HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma
Conditions: Hepatic Arterial Infusion Chemotherapy; Liver Metastases; Esophageal Squamous Cell Carcinoma Interventions: Drug: HAIC combined with intravenous PD-1 Sponsors: Peking University Cancer Hospital& Institute; Innovent Biologics (Suzhou) Co. Ltd. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials

Gut microbiota in children with autoimmune liver disease and its effect on treatment response
Conditions: Autoimmune Diseases Interventions: Other: No intervention Sponsors: Institute of Liver and Biliary Sciences, India Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials

A Study of Ga-68 Dolacga to Evaluate Liver Reserve Function in Patients With HCC Before and After Proton Therapy
Conditions: Hepatic Carcinoma Interventions: Drug: Ga-68 Dolacga Injection Sponsors: National Atomic Research Institute, Taiwan Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials

Contingency Management to Incentivise Treatment Adherence in Alcohol-related Liver Disease
Conditions: Alcohol-related Liver Disease Interventions: Behavioral: Contingency management Sponsors: King ' s College Hospital NHS Trust Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials

Real-World Validation of a Prognostic Prediction Model for Patients With Acute Exacerbations of Chronic Liver Disease
Conditions: Chronic Liver Disease and Cirrhosis Sponsors: Shanghai Jiao Tong University School of Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials