Depletion of Liver Fat in Type 2 Diabetes
Conditions: Type2diabetes; Obesity Interventions: Behavioral: Very-low calorie diet Sponsors: Rigshospitalet, Denmark; Diabetesforeningen; Canadian Institutes of Health Research (CIHR); Region Hovedstadens Forskningsfond Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study
Conditions: Cardiovascular Diseases; Metabolic Syndrome; Non-Alcoholic Fatty Liver Disease Interventions: Behavioral: Digital wearable and AI-human symbiotic lifestyle intervention Sponsors: National University Hospital, Singapore; National University of Singapore Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Coherus Presents Positive Phase 2 Clinical Data on Casdozokitug, a First-in-Class IL-27-Targeted Antibody
Data demonstrate early activity with casdozokitug/atezolizumab/bevacizumab; 38% objective response rate including three complete responses
Data support casdozo as a promising novel immuno-oncology agent with clinical activity in liver cancer that... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - January 18, 2024 Category: Pharmaceuticals Source Type: clinical trials
MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases
Conditions: Metastatic Colorectal Cancer Interventions: Diagnostic Test: Magnetic Resonance Elastography and routine MRI Sponsors: Shengjing Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Efficacy of Virtual Reality Exercises on Sarcopenia in Patients With Liver Transplantation
Conditions: Sarcopenia Interventions: Other: Virtual Reality exercise; Other: conventional treatment Sponsors: Cairo University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Impact of Perioperative Body Composition Abnormalities on Patient Outcomes After Liver Transplantation
Conditions: Liver Transplantation; Body Composition Sponsors: Zhejiang University; First Affiliated Hospital of Zhejiang University; Shulan (Hangzhou) Hospital; The Affiliated Hospital of Qingdao University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Tacrolimus versus mycophenolate for AutoImmune hepatitis patients with incompLete response On first-line therapy (TAILOR study): a study protocol for a phase III, open-label, multicentre, randomised controlled trial
DiscussionThis is the first randomised controlled trial comparing two second-line therapies for AIH. Currently, second-line treatment is based on retrospective cohort studies. The rarity of AIH is the main issue in clinical research for alternative treatment options. The results of this trial can be implemented in existing international clinical guidelines.Trial registrationClinicalTrials.govNCT05221411. Retrospectively registered on 3 February 2022; EudraCT number 2021 –003420-33. Prospectively registered on 16 June 2021. (Source: Trials)
Source: Trials - January 17, 2024 Category: Research Source Type: clinical trials
3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension
Conditions: Cirrhosis; Liver Portal Hypertension Interventions: Device: 3D-MRE; Device: HVPG; Device: 2D-MRE; Device: HVPG Sponsors: Shengjing Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
A Retrospective Study on the Treatment of Intermediate and Advanced Liver Cancer.
Conditions: Carcinoma, Hepatocellular Interventions: Other: Immunotherapy, targeted therapy. Sponsors: Qianfoshan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Diagnosis of Adrenal Insufficiency in Liver Cirrhosis Patients
Conditions: Adrenal Insufficiency; Liver Cirrhosis Interventions: Diagnostic Test: rapid ACTH stimulation test Sponsors: Seoul National University Hospital; Korea Institute of Science and Technology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Liver Steatosis in Pediatric CD Patients
Conditions: Celiac Disease in Children; Non-Alcoholic Fatty Liver Disease Interventions: Behavioral: Gluten-free diet Sponsors: University of Palermo; ARNAS Civico Di Cristina Benfratelli Hospital; Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Monitoring Changes in Hepatic Steatosis Using Continuous Controlled Attenuation Parameter
Conditions: Fatty Liver Interventions: Behavioral: Lifestyle modification programme Sponsors: Chinese University of Hong Kong Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials
Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases
Conditions: Colorectal Cancer; Colorectal Neoplasms Malignant; Liver Metastasis Colon Cancer; Liver Metastases Interventions: Procedure: Staged resection; Procedure: Simultaneous resection Sponsors: Oslo University Hospital; University of Oslo; Haukeland University Hospital; St. Olavs Hospital; Helse Stavanger HF; University Hospital, Akershus Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
A Phase IV Study of Huazhi Rougan Granule in the Treatment of Non-alcoholic Simple Fatty Liver
Conditions: Efficacy and Safety Interventions: Drug: Huazhi Rougan granule Sponsors: Shandong New Time Pharmaceutical Co., LTD Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
Conditions: Hepatoblastoma; Hepatocellular Carcinoma; Wilms Tumor; Malignant Rhabdoid Tumor; Yolk Sac Tumor; Rhabdomyosarcoma; Liposarcoma; Embryonal Sarcoma of Liver Interventions: Genetic: 21.15.GPC3-CAR T cells Sponsors: Baylor College of Medicine; Center for Cell and Gene Therapy, Baylor College of Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
